 Adenosine Deaminase
"Adenosine Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the hydrolysis of ADENOSINE to INOSINE with the elimination of AMMONIA.
| Descriptor ID |
D000243
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| MeSH Number(s) |
D08.811.277.151.486.075
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| Concept/Terms |
Adenosine Deaminase- Adenosine Deaminase
- Deaminase, Adenosine
- Adenosine Aminohydrolase
- Aminohydrolase, Adenosine
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Below are MeSH descriptors whose meaning is more general than "Adenosine Deaminase".
Below are MeSH descriptors whose meaning is more specific than "Adenosine Deaminase".
This graph shows the total number of publications written about "Adenosine Deaminase" by people in this website by year, and whether "Adenosine Deaminase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1983 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1986 | 1 | 0 | 1 | | 1987 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1990 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 |
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Below are the most recent publications written about "Adenosine Deaminase" by people in Profiles.
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Mallipeddi PL, Joshi M, Briggs JM. Pharmacophore-based virtual screening to aid in the identification of unknown protein function. Chem Biol Drug Des. 2012 Dec; 80(6):828-42.
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Zhou CC, Chang J, Mi T, Abbasi S, Gu D, Huang L, Zhang W, Kellems RE, Schwartz RJ, Xia Y. Targeted expression of Cre recombinase provokes placental-specific DNA recombination in transgenic mice. PLoS One. 2012; 7(2):e29236.
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Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Detrimental effects of adenosine signaling in sickle cell disease. Nat Med. 2011 Jan; 17(1):79-86.
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Marrone TJ, Straatsma TP, Briggs JM, Wilson DK, Quiocho FA, McCammon JA. Theoretical study of inhibition of adenosine deaminase by (8R)-coformycin and (8R)-deoxycoformycin. J Med Chem. 1996 Jan 05; 39(1):277-84.
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Virta-Pearlman VJ, Gunaratne PH, Chinault AC. Analysis of a replication initiation sequence from the adenosine deaminase region of the mouse genome. Mol Cell Biol. 1993 Oct; 13(10):5931-42.
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al-Ubaidi MR, Ramamurthy V, Maa MC, Ingolia DE, Chinsky JM, Martin BD, Kellems RE. Structural and functional analysis of the murine adenosine deaminase gene. Genomics. 1990 Aug; 7(4):476-85.
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Stallings RL, Siciliano MJ, Frazier ML, al-Ubaidi MR, Kellems RE. Hypomethylation and ADA gene expression in mouse CAK cells. Somat Cell Mol Genet. 1989 Jan; 15(1):1-11.
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Donaldson J, Hill SJ, Brown AM. Kinetic studies on the mechanism by which histamine H1 receptors potentiate cyclic AMP accumulation in guinea pig cerebral cortical slices. Mol Pharmacol. 1988 Jun; 33(6):626-33.
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Hill SJ, Kendall DA. Studies on the adenosine-receptor mediating the augmentation of histamine-induced inositol phospholipid hydrolysis in guinea-pig cerebral cortex. Br J Pharmacol. 1987 Jul; 91(3):661-9.
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Ingolia DE, Al-Ubaidi MR, Yeung CY, Bigo HA, Wright D, Kellems RE. Molecular cloning of the murine adenosine deaminase gene from a genetically enriched source: identification and characterization of the promoter region. Mol Cell Biol. 1986 Dec; 6(12):4458-66.
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