 Angiotensin II
"Angiotensin II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.
| Descriptor ID |
D000804
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| MeSH Number(s) |
D06.472.699.094.078 D12.644.400.070.078 D12.644.456.073.041 D12.644.548.058.078 D12.776.641.650.070.078 D23.469.050.050.050
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| Concept/Terms |
Angiotensin II- Angiotensin II
- Angiotensin-(1-8) Octapeptide
- ANG-(1-8)Octapeptide
Angiotensin II, Ile(5)-- Angiotensin II, Ile(5)-
- Isoleucyl(5)-Angiotensin II
- Isoleucine(5)-Angiotensin
- 5-L-Isoleucine Angiotensin II
- 5 L Isoleucine Angiotensin II
- Angiotensin II, 5-L-Isoleucine
- II, 5-L-Isoleucine Angiotensin
- Angiotensin II, Isoleucine(5)-
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Below are MeSH descriptors whose meaning is more general than "Angiotensin II".
Below are MeSH descriptors whose meaning is more specific than "Angiotensin II".
This graph shows the total number of publications written about "Angiotensin II" by people in this website by year, and whether "Angiotensin II" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 | | 1981 | 4 | 0 | 4 | | 1982 | 1 | 0 | 1 | | 1983 | 0 | 5 | 5 | | 1984 | 1 | 0 | 1 | | 1985 | 1 | 2 | 3 | | 1991 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 1 | 0 | 1 | | 2003 | 2 | 1 | 3 | | 2008 | 2 | 0 | 2 | | 2011 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 2 | 0 | 2 |
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Below are the most recent publications written about "Angiotensin II" by people in Profiles.
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Abkhezr M, Dryer SE. Angiotensin II and canonical transient receptor potential-6 activation stimulate release of a signal transducer and activator of transcription 3-activating factor from mouse podocytes. Mol Pharmacol. 2014 Aug; 86(2):150-8.
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Anderson M, Roshanravan H, Khine J, Dryer SE. Angiotensin II activation of TRPC6 channels in rat podocytes requires generation of reactive oxygen species. J Cell Physiol. 2014 Apr; 229(4):434-42.
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Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, Iseki S, Schwartz RJ, Okamoto H, Sasaki T, Matsui O, Asano M, Adams RH, Takakura N, Takuwa Y. Endothelial PI3K-C2a, a class II PI3K, has an essential role in angiogenesis and vascular barrier function. Nat Med. 2012 Oct; 18(10):1560-9.
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Javkhedkar AA, Lokhandwala MF, Banday AA. Defective nitric oxide production impairs angiotensin II-induced Na-K-ATPase regulation in spontaneously hypertensive rats. Am J Physiol Renal Physiol. 2012 Jan 01; 302(1):F47-51.
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Banday AA, Lokhandwala MF. Angiotensin II-mediated biphasic regulation of proximal tubular Na+/H+ exchanger 3 is impaired during oxidative stress. Am J Physiol Renal Physiol. 2011 Aug; 301(2):F364-70.
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Banday AA, Lokhandwala MF. Loss of biphasic effect on Na/K-ATPase activity by angiotensin II involves defective angiotensin type 1 receptor-nitric oxide signaling. Hypertension. 2008 Dec; 52(6):1099-105.
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Banday AA, Lokhandwala MF. Oxidative stress-induced renal angiotensin AT1 receptor upregulation causes increased stimulation of sodium transporters and hypertension. Am J Physiol Renal Physiol. 2008 Sep; 295(3):F698-706.
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Flesch M, Höper A, Dell'Italia L, Evans K, Bond R, Peshock R, Diwan A, Brinsa TA, Wei CC, Sivasubramanian N, Spinale FG, Mann DL. Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 2003 Aug 05; 108(5):598-604.
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Tallam LS, Jandhyala BS. Influence of plasma insulin levels on antinatriuretic and vasoconstrictor actions of angiotensin-II. Clin Exp Hypertens. 2003 May; 25(4):257-70.
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Becker M, Umrani D, Lokhandwala MF, Hussain T. Increased renal angiotensin II AT1 receptor function in obese Zucker rat. Clin Exp Hypertens. 2003 Jan; 25(1):35-47.
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