Deoxyribonuclease I
"Deoxyribonuclease I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.
| Descriptor ID |
D003850
|
| MeSH Number(s) |
D08.811.277.352.335.350.250
|
| Concept/Terms |
Deoxyribonuclease I- Deoxyribonuclease I
- DNAase I
- Pancreatic DNase
- DNase, Pancreatic
- Thymonuclease
- DNA Endonuclease
- Endonuclease, DNA
- DNase I
Nickase- Nickase
- DNA Nicking Enzyme
- Endonuclease I
|
Below are MeSH descriptors whose meaning is more general than "Deoxyribonuclease I".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonuclease I".
This graph shows the total number of publications written about "Deoxyribonuclease I" by people in this website by year, and whether "Deoxyribonuclease I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1985 | 0 | 1 | 1 |
| 1991 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxyribonuclease I" by people in Profiles.
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Mach CM, Hargrove BW, Kunkel GR. The Small RNA gene activator protein, SphI postoctamer homology-binding factor/selenocysteine tRNA gene transcription activating factor, stimulates transcription of the human interferon regulatory factor-3 gene. J Biol Chem. 2002 Feb 15; 277(7):4853-8.
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Chow KL, Hogan ME, Schwartz RJ. Phased cis-acting promoter elements interact at short distances to direct avian skeletal alpha-actin gene transcription. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1301-5.
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Sen S, Siciliano MJ, Johnston DA, Schwartz RJ, Kuo T. The expression and chromatin structure of the chicken glyceraldehyde-3-phosphate dehydrogenase gene in mouse cells. J Biol Chem. 1985 Mar 10; 260(5):3071-8.