Genes, Homeobox
"Genes, Homeobox" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
Descriptor ID |
D005801
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MeSH Number(s) |
G05.360.340.024.340.230.500
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Concept/Terms |
Genes, Homeobox- Genes, Homeobox
- Gene, Homeobox
- Homeobox Gene
- Homeobox Genes
- Genes, Homeotic
- Gene, Homeotic
- Homeotic Gene
- Hox Genes
- Gene, Hox
- Genes, Hox
- Hox Gene
- Genes, Homeo Box
- Gene, Homeo Box
- Homeo Box Gene
- Homeo Box Genes
- Homeotic Genes
Homeo Box Sequence- Homeo Box Sequence
- Homeo Box Sequences
- Sequences, Homeo Box
- Homeo Boxes
- Sequence, Homeo Box
- Homeobox Sequence
- Homeobox Sequences
- Sequence, Homeobox
- Sequences, Homeobox
- Homeoboxes
- Homeo Box
- Homeobox
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Below are MeSH descriptors whose meaning is more general than "Genes, Homeobox".
Below are MeSH descriptors whose meaning is more specific than "Genes, Homeobox".
This graph shows the total number of publications written about "Genes, Homeobox" by people in this website by year, and whether "Genes, Homeobox" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 | 2001 | 0 | 1 | 1 | 2002 | 4 | 0 | 4 | 2003 | 1 | 0 | 1 | 2005 | 1 | 1 | 2 |
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Below are the most recent publications written about "Genes, Homeobox" by people in Profiles.
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Stanfel MN, Moses KA, Schwartz RJ, Zimmer WE. Regulation of organ development by the NKX-homeodomain factors: an NKX code. Cell Mol Biol (Noisy-le-grand). 2005 Oct 24; Suppl 51:OL785-99.
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Maclean JA, Chen MA, Wayne CM, Bruce SR, Rao M, Meistrich ML, Macleod C, Wilkinson MF. Rhox: a new homeobox gene cluster. Cell. 2005 Feb 11; 120(3):369-82.
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Rao MK, Wayne CM, Meistrich ML, Wilkinson MF. Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo. Mol Endocrinol. 2003 Feb; 17(2):223-33.
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Lo PC, Skeath JB, Gajewski K, Schulz RA, Frasch M. Homeotic genes autonomously specify the anteroposterior subdivision of the Drosophila dorsal vessel into aorta and heart. Dev Biol. 2002 Nov 15; 251(2):307-19.
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Wayne CM, MacLean JA, Cornwall G, Wilkinson MF. Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis. Gene. 2002 Nov 13; 301(1-2):1-11.
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Rao MK, Wayne CM, Wilkinson MF. Pem homeobox gene regulatory sequences that direct androgen-dependent developmentally regulated gene expression in different subregions of the epididymis. J Biol Chem. 2002 Dec 13; 277(50):48771-8.
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Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, Mullins MC, Epstein JA. Hop is an unusual homeobox gene that modulates cardiac development. Cell. 2002 Sep 20; 110(6):713-23.
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Gajewski K, Zhang Q, Choi CY, Fossett N, Dang A, Kim YH, Kim Y, Schulz RA. Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis. Dev Biol. 2001 May 15; 233(2):425-36.
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Reecy JM, Li X, Yamada M, DeMayo FJ, Newman CS, Harvey RP, Schwartz RJ. Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5. Development. 1999 Feb; 126(4):839-49.
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