Lactose Intolerance
"Lactose Intolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The condition resulting from the absence or deficiency of LACTASE in the MUCOSA cells of the GASTROINTESTINAL TRACT, and the inability to break down LACTOSE in milk for ABSORPTION. Bacterial fermentation of the unabsorbed lactose leads to symptoms that range from a mild indigestion (DYSPEPSIA) to severe DIARRHEA. Lactose intolerance may be an inborn error or acquired.
Descriptor ID |
D007787
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MeSH Number(s) |
C06.405.469.637.506 C16.320.565.202.589 C18.452.603.506 C18.452.648.202.589
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Concept/Terms |
Lactose Intolerance- Lactose Intolerance
- Intolerance, Lactose
- Alactasia
- Hypolactasia
- Milk Sugar Intolerance
- Lactose Malabsorption
- Malabsorption, Lactose
- Dairy Product Intolerance
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Below are MeSH descriptors whose meaning is more general than "Lactose Intolerance".
Below are MeSH descriptors whose meaning is more specific than "Lactose Intolerance".
This graph shows the total number of publications written about "Lactose Intolerance" by people in this website by year, and whether "Lactose Intolerance" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2004 | 2 | 1 | 3 | 2005 | 0 | 1 | 1 | 2006 | 3 | 0 | 3 | 2008 | 1 | 0 | 1 | 2009 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2015 | 2 | 0 | 2 |
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Below are the most recent publications written about "Lactose Intolerance" by people in Profiles.
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Szilagyi A. Adaptation to Lactose in Lactase Non Persistent People: Effects on Intolerance and the Relationship between Dairy Food Consumption and Evalution of Diseases. Nutrients. 2015 Aug 13; 7(8):6751-79.
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Szilagyi A. Adult lactose digestion status and effects on disease. Can J Gastroenterol Hepatol. 2015 Apr; 29(3):149-56.
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Szilagyi A, Shrier I, Heilpern D, Je J, Park S, Chong G, Lalonde C, Cote LF, Lee B. Differential impact of lactose/lactase phenotype on colonic microflora. Can J Gastroenterol. 2010 Jun; 24(6):373-9.
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Szilagyi A, Shrier I, Chong G, Je JS, Park S, Heilpern D, Lalonde C, Cote LF, Lee B. Lack of effect of lactose digestion status on baseline fecal micoflora. Can J Gastroenterol. 2009 Nov; 23(11):753-9.
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Shrier I, Szilagyi A, Correa JA. Impact of lactose containing foods and the genetics of lactase on diseases: an analytical review of population data. Nutr Cancer. 2008; 60(3):292-300.
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Szilagyi A, Malolepszy P, Hamard E, Xue X, Hilzenrat N, Ponniah M, MacNamara E, Chong G. Comparison of a real-time polymerase chain reaction assay for lactase genetic polymorphism with standard indirect tests for lactose maldigestion. Clin Gastroenterol Hepatol. 2007 Feb; 5(2):192-6.
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Szilagyi A, Nathwani U, Vinokuroff C, Correa JA, Shrier I. Evaluation of relationships among national colorectal cancer mortality rates, genetic lactase non-persistence status, and per capita yearly milk and milk product consumption. Nutr Cancer. 2006; 55(2):151-6.
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Szilagyi A, Nathwani U, Vinokuroff C, Correa JA, Shrier I. The effect of lactose maldigestion on the relationship between dairy food intake and colorectal cancer: a systematic review. Nutr Cancer. 2006; 55(2):141-50.
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Szilagyi A, Malolepszy P, Yesovitch S, Nathwani U, Vinokuroff C, Cohen A, Xue X. Inverse dose effect of pretest dietary lactose intake on breath hydrogen results and symptoms in lactase nonpersistent subjects. Dig Dis Sci. 2005 Nov; 50(11):2178-82.
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Szilagyi A, Cohen A, Vinokuroff C, Ahmad D, Nathwani U, Yesovitch S. Deadaption and readaptation with lactose, but no cross-adaptation to lactulose: a case of occult colonic bacterial adaptation. Can J Gastroenterol. 2004 Nov; 18(11):677-80.
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