 Methotrexate
"Methotrexate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
| Descriptor ID |
D008727
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| MeSH Number(s) |
D03.438.733.631.192.500
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| Concept/Terms |
Methotrexate Sodium- Methotrexate Sodium
- Sodium, Methotrexate
- Methotrexate, Disodium Salt
- Methotrexate, Sodium Salt
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Below are MeSH descriptors whose meaning is more general than "Methotrexate".
Below are MeSH descriptors whose meaning is more specific than "Methotrexate".
This graph shows the total number of publications written about "Methotrexate" by people in this website by year, and whether "Methotrexate" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methotrexate" by people in Profiles.
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Kadakia A, Rajan SS, Abughosh S, Du XL, Johnson ML. CMF-regimen preferred as first-course chemotherapy for older and sicker women with breast cancer: Findings from a SEER-Medicare-based population study. Am J Clin Oncol. 2015 Apr; 38(2):165-73.
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Hou JK, Kramer JR, Richardson P, Sansgiry S, El-Serag HB. Myelosuppression monitoring after immunomodulator initiation in veterans with inflammatory bowel disease: a national practice audit. Aliment Pharmacol Ther. 2012 Dec; 36(11-12):1049-56.
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Rubin RC, Ommaya AK, Henderson ES, Bering EA, Rall DP. Cerebrospinal fluid perfusion for central nervous system neoplasms. Neurology. 1966 Jul; 16(7):680-92.
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Ommaya AK, Rubin RC, Henderson ES, Rall DP, Gieseke FG, Bering EA, Bagan M. A new approach to the treatment of inoperable brain tumors. Med Ann Dist Columbia. 1965 Oct; 34(10):455-8.
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