Methysergide
"Methysergide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.
| Descriptor ID |
D008784
|
| MeSH Number(s) |
D03.132.327.287.689 D03.549.439.689
|
| Concept/Terms |
Methysergide- Methysergide
- Methylmethylergonovine
- Dimethylergometrin
Sansert- Sansert
- Novartis Brand of Methysergide Maleate
- Desril
- Alliance Brand of Methysergide Maleate
- Deseril
- Désernil-Sandoz
- Désernil Sandoz
|
Below are MeSH descriptors whose meaning is more general than "Methysergide".
Below are MeSH descriptors whose meaning is more specific than "Methysergide".
This graph shows the total number of publications written about "Methysergide" by people in this website by year, and whether "Methysergide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 0 | 1 | 1 |
| 1983 | 0 | 1 | 1 |
| 1987 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methysergide" by people in Profiles.
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Jandhyala BS, Kivlighn SD. Antagonism by methysergide of neurogenic vasoconstriction in the dog forelimb. Fed Proc. 1987 Feb; 46(2):276-80.
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Dobbins DE, Adamski SW, Lokhandwala MF, Grega GJ. Evidence that serotonin receptors mediate the cutaneous vasoconstriction produced by 5-hydroxytryptamine in canine forelimbs. Circ Res. 1983 Oct; 53(4):473-81.
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Martinez AA, Lokhandwala MF. Evidence for a presynaptic inhibitory action of 5-hydroxytryptamine on sympathetic neurotransmission to the myocardium. Eur J Pharmacol. 1980 May 16; 63(4):303-11.
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Brune GG, Sill V. [Carcinoid syndrome. Tryptophan metabolism--pathogenesis of concomitant symptoms--combination of tumours]. Munch Med Wochenschr. 1972 May 19; 114(20):973-8.