Neural Crest
"Neural Crest" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The two longitudinal ridges along the PRIMITIVE STREAK appearing near the end of GASTRULATION during development of nervous system (NEURULATION). The ridges are formed by folding of NEURAL PLATE. Between the ridges is a neural groove which deepens as the fold become elevated. When the folds meet at midline, the groove becomes a closed tube, the NEURAL TUBE.
Descriptor ID |
D009432
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MeSH Number(s) |
A16.627
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Concept/Terms |
Neural Crest- Neural Crest
- Crest, Neural
- Crests, Neural
- Neural Crests
Neural Fold- Neural Fold
- Fold, Neural
- Folds, Neural
- Neural Folds
Neural Groove- Neural Groove
- Groove, Neural
- Grooves, Neural
- Neural Grooves
Neural Crest Cells- Neural Crest Cells
- Cell, Neural Crest
- Cells, Neural Crest
- Neural Crest Cell
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Below are MeSH descriptors whose meaning is more general than "Neural Crest".
Below are MeSH descriptors whose meaning is more specific than "Neural Crest".
This graph shows the total number of publications written about "Neural Crest" by people in this website by year, and whether "Neural Crest" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1990 | 0 | 1 | 1 | 1992 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2010 | 1 | 0 | 1 | 2011 | 1 | 0 | 1 | 2012 | 1 | 0 | 1 | 2013 | 1 | 1 | 2 |
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Below are the most recent publications written about "Neural Crest" by people in Profiles.
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Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X. Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects. Dev Biol. 2013 Nov 15; 383(2):239-52.
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Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, VanDusen NJ, Snider P, Schwartz RJ, Conway SJ, Field LJ, Yoder MC, Firulli AB, Carlesso N, Towbin JA, Shou W. Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development. 2013 May; 140(9):1946-57.
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Munoz WA, Kloc M, Cho K, Lee M, Hofmann I, Sater A, Vleminckx K, McCrea PD. Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues. PLoS One. 2012; 7(4):e34342.
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Olaopa M, Zhou HM, Snider P, Wang J, Schwartz RJ, Moon AM, Conway SJ. Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation. Dev Biol. 2011 Aug 15; 356(2):308-22.
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Zhang J, Chang JY, Huang Y, Lin X, Luo Y, Schwartz RJ, Martin JF, Wang F. The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation. Circ Res. 2010 Nov 12; 107(10):1209-19.
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Zhang J, Lin Y, Zhang Y, Lan Y, Lin C, Moon AM, Schwartz RJ, Martin JF, Wang F. Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. Development. 2008 Nov; 135(21):3611-22.
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Ilagan R, Abu-Issa R, Brown D, Yang YP, Jiao K, Schwartz RJ, Klingensmith J, Meyers EN. Fgf8 is required for anterior heart field development. Development. 2006 Jun; 133(12):2435-45.
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Keller R, Shih J, Sater AK, Moreno C. Planar induction of convergence and extension of the neural plate by the organizer of Xenopus. Dev Dyn. 1992 Mar; 193(3):218-34.
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Keller R, Shih J, Sater A. The cellular basis of the convergence and extension of the Xenopus neural plate. Dev Dyn. 1992 Mar; 193(3):199-217.
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Sater AK, Jacobson AG. The restriction of the heart morphogenetic field in Xenopus laevis. Dev Biol. 1990 Aug; 140(2):328-36.
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