Nicotine
"Nicotine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
Descriptor ID |
D009538
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MeSH Number(s) |
D03.132.760.570 D03.383.725.518
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicotine".
Below are MeSH descriptors whose meaning is more specific than "Nicotine".
This graph shows the total number of publications written about "Nicotine" by people in this website by year, and whether "Nicotine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 | 1999 | 1 | 0 | 1 | 2004 | 2 | 0 | 2 | 2005 | 2 | 1 | 3 | 2006 | 5 | 0 | 5 | 2007 | 3 | 0 | 3 | 2008 | 3 | 2 | 5 | 2009 | 4 | 1 | 5 | 2010 | 5 | 0 | 5 | 2011 | 6 | 0 | 6 | 2012 | 3 | 0 | 3 | 2013 | 3 | 1 | 4 | 2014 | 1 | 2 | 3 | 2015 | 2 | 0 | 2 | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nicotine" by people in Profiles.
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Kanlikilicer P, Zhang D, Dragomir A, Akay YM, Akay M. Gene expression profiling of midbrain dopamine neurons upon gestational nicotine exposure. Med Biol Eng Comput. 2017 Mar; 55(3):467-482.
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Delitto D, Zhang D, Han S, Black BS, Knowlton AE, Vlada AC, Sarosi GA, Behrns KE, Thomas RM, Lu X, Liu C, George TJ, Hughes SJ, Wallet SM, Trevino JG. Nicotine Reduces Survival via Augmentation of Paracrine HGF-MET Signaling in the Pancreatic Cancer Microenvironment. Clin Cancer Res. 2016 Apr 01; 22(7):1787-99.
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Duke AN, Johnson MW, Reissig CJ, Griffiths RR. Nicotine reinforcement in never-smokers. Psychopharmacology (Berl). 2015 Dec; 232(23):4243-52.
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Reitzel LR, Nguyen N, Eischen S, Thomas J, Okuyemi KS. Is smoking cessation associated with worse comorbid substance use outcomes among homeless adults? Addiction. 2014 Dec; 109(12):2098-104.
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Guillot CR, Zvolensky MJ, Leventhal AM. Differential associations between components of anxiety sensitivity and smoking-related characteristics. Addict Behav. 2015 Jan; 40:39-44.
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Zhang D, Dragomir A, Akay YM, Akay M. Nicotine exposure increases the complexity of dopamine neurons in the parainterfascicular nucleus (PIF) sub-region of VTA. J Neuroeng Rehabil. 2014 Jun 12; 11:103.
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Alzoubi KH, Alkadhi KA. Chronic nicotine treatment reverses hypothyroidism-induced impairment of L-LTP induction phase: critical role of CREB. Mol Neurobiol. 2014 Jun; 49(3):1245-55.
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Brown RA, Reed KM, Bloom EL, Minami H, Strong DR, Lejuez CW, Kahler CW, Zvolensky MJ, Gifford EV, Hayes SC. Development and preliminary randomized controlled trial of a distress tolerance treatment for smokers with a history of early lapse. Nicotine Tob Res. 2013 Dec; 15(12):2005-15.
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Langdon KJ, Leventhal AM, Stewart S, Rosenfield D, Steeves D, Zvolensky MJ. Anhedonia and anxiety sensitivity: prospective relationships to nicotine withdrawal symptoms during smoking cessation. J Stud Alcohol Drugs. 2013 May; 74(3):469-78.
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Peters RJ, Meshack A, Lin MT, Hill M, Abughosh S. The social norms and beliefs of teenage male electronic cigarette use. J Ethn Subst Abuse. 2013; 12(4):300-7.
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