 Rats, Inbred SHR
"Rats, Inbred SHR" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A strain of Rattus norvegicus with elevated blood pressure used as a model for studying hypertension and stroke.
| Descriptor ID |
D011918
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| MeSH Number(s) |
B01.050.050.199.520.760.300 B01.050.150.900.649.865.635.505.700.400.300
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| Concept/Terms |
Rats, Inbred SHR- Rats, Inbred SHR
- Inbred SHR Rat
- Inbred SHR Rats
- Rat, Inbred SHR
- SHR Rat, Inbred
- SHR Rats, Inbred
- Rats, SHR
- Rat, SHR
- SHR Rat
- SHR Rats
- Rats, Spontaneously Hypertensive
- Rat, Spontaneously Hypertensive
- Spontaneously Hypertensive Rat
- Spontaneously Hypertensive Rats
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Below are MeSH descriptors whose meaning is more general than "Rats, Inbred SHR".
Below are MeSH descriptors whose meaning is more specific than "Rats, Inbred SHR".
This graph shows the total number of publications written about "Rats, Inbred SHR" by people in this website by year, and whether "Rats, Inbred SHR" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1984 | 0 | 1 | 1 | | 1988 | 0 | 1 | 1 | | 1992 | 1 | 2 | 3 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 3 | 3 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1998 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Rats, Inbred SHR" by people in Profiles.
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Chobanian HR, Guo Y, Pio B, Tang H, Teumelsan N, Clements M, Frie J, Ferguson R, Guo Z, Thomas-Fowlkes BS, Felix JP, Liu J, Kohler M, Priest B, Hampton C, Pai LY, Corona A, Metzger J, Tong V, Joshi EM, Xu L, Owens K, Maloney K, Sullivan K, Pasternak A. The design and synthesis of novel spirocyclic heterocyclic sulfone ROMK inhibitors as diuretics. Bioorg Med Chem Lett. 2017 Feb 15; 27(4):1109-1114.
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Javkhedkar AA, Quiroz Y, Rodriguez-Iturbe B, Vaziri ND, Lokhandwala MF, Banday AA. Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol. 2015 May 15; 308(10):R840-6.
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Bhatt SR, Lokhandwala MF, Banday AA. Vascular oxidative stress upregulates angiotensin II type I receptors via mechanisms involving nuclear factor kappa B. Clin Exp Hypertens. 2014; 36(6):367-73.
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Javkhedkar AA, Lokhandwala MF, Banday AA. Defective nitric oxide production impairs angiotensin II-induced Na-K-ATPase regulation in spontaneously hypertensive rats. Am J Physiol Renal Physiol. 2012 Jan 01; 302(1):F47-51.
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Bhatt SR, Lokhandwala MF, Banday AA. Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats. Eur J Pharmacol. 2011 Sep 30; 667(1-3):258-64.
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Alkadhi K, Alzoubi K. Role of long-term potentiation of sympathetic ganglia (gLTP) in hypertension. Clin Exp Hypertens. 2007 Jul; 29(5):267-86.
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Xiao RP, Zhang SJ, Chakir K, Avdonin P, Zhu W, Bond RA, Balke CW, Lakatta EG, Cheng H. Enhanced G(i) signaling selectively negates beta2-adrenergic receptor (AR)--but not beta1-AR-mediated positive inotropic effect in myocytes from failing rat hearts. Circulation. 2003 Sep 30; 108(13):1633-9.
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Alkadhi KA, Otoom SA, Tanner FL, Sockwell D, Hogan YH. Inhibition of ganglionic long-term potentiation decreases blood pressure in spontaneously hypertensive rats. Exp Biol Med (Maywood). 2001 Dec; 226(11):1024-30.
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Hussain T, Kansra V, Lokhandwala MF. Renal dopamine receptor signaling mechanisms in spontaneously hypertensive and Fischer 344 old rats. Clin Exp Hypertens. 1999 Jan-Feb; 21(1-2):25-36.
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Hussain T, Lokhandwala MF. Renal dopamine receptor function in hypertension. Hypertension. 1998 Aug; 32(2):187-97.
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