 Renin
"Renin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
| Descriptor ID |
D012083
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| MeSH Number(s) |
D08.811.277.656.074.500.780 D08.811.277.656.300.048.780 D08.811.277.656.837.750
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| Concept/Terms |
Renin- Renin
- Angiotensin-Forming Enzyme
- Angiotensin Forming Enzyme
- Angiotensinogenase
Prorenin- Prorenin
- Inactive Renin
- Renin, Inactive
- Big Renin
- Renin, Big
- Cryorenin
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Below are MeSH descriptors whose meaning is more general than "Renin".
Below are MeSH descriptors whose meaning is more specific than "Renin".
This graph shows the total number of publications written about "Renin" by people in this website by year, and whether "Renin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1981 | 0 | 1 | 1 | | 1982 | 0 | 1 | 1 | | 1983 | 0 | 1 | 1 | | 1984 | 1 | 0 | 1 | | 1986 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Renin" by people in Profiles.
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Xiong J, Xia M, Yi F, Abais JM, Li N, Boini KM, Li PL. Regulation of renin release via cyclic ADP-ribose-mediated signaling: evidence from mice lacking CD38 gene. Cell Physiol Biochem. 2013; 31(1):44-55.
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Flesch M, Höper A, Dell'Italia L, Evans K, Bond R, Peshock R, Diwan A, Brinsa TA, Wei CC, Sivasubramanian N, Spinale FG, Mann DL. Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor. Circulation. 2003 Aug 05; 108(5):598-604.
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Tallam LS, Jandhyala BS. Exaggerated natriuresis after selective AT1 receptor blockade in Dahl salt-sensitive rats. Clin Exp Hypertens. 2001 Nov; 23(8):623-31.
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Tallam LS, Jandhyala BS. Significance of exaggerated natriuresis after angiotensin AT1 receptor blockade or angiotensin- converting enzyme inhibition in obese Zucker rats. Clin Exp Pharmacol Physiol. 2001 May-Jun; 28(5-6):433-40.
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Denton DA, Eichberg JW, Shade R, Weisinger RS. Sodium appetite in response to sodium deficiency in baboons. Am J Physiol. 1993 Mar; 264(3 Pt 2):R539-43.
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Jandhyala BS. Is expansion of extracellular fluid volume essential for the development of "volume expanded" hypertension? A commentary. Clin Exp Hypertens A. 1986; 8(3):457-72.
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Buckley JP, Jandhyala BS, Doursout MF, Huang YK, Chelly JE. Effects of brain renin-angiotensin on cardiovascular function and saline intake in awake dogs. J Physiol (Paris). 1984; 79(6):485-90.
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Eikenburg DC, Lokhandwala MF. Effects of captopril on vascular noradrenergic transmission during the development of two-kidney, one clip Goldblatt hypertension in rats. J Hypertens. 1983 Aug; 1(2):115-22.
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Eikenburg DC, Ekas RD, Lokhandwala MF. Alterations in prejunctional responsiveness to angiotensin II during the development of 2-kidney, 1-clip Goldblatt hypertension in rats. J Pharmacol Exp Ther. 1982 Dec; 223(3):766-73.
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Hamed AT, Lokhandwala MF, Jandhyala BS. Comparative evaluation of the factors regulating vascular resistance in dogs, anesthetized with morphine-chloralose or pentobarbital. Arch Int Pharmacodyn Ther. 1981 Feb; 249(2):264-74.
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