 Reserpine
"Reserpine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
| Descriptor ID |
D012110
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| MeSH Number(s) |
D03.132.436.681.933.500 D03.438.473.402.681.933.500
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| Concept/Terms |
V-Serp- V-Serp
- V Serp
- Vangarde Brand of Reserpine
Serpivite- Serpivite
- Vitarine Brand of Reserpine
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Below are MeSH descriptors whose meaning is more general than "Reserpine".
Below are MeSH descriptors whose meaning is more specific than "Reserpine".
This graph shows the total number of publications written about "Reserpine" by people in this website by year, and whether "Reserpine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1987 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 2 | 0 | 2 |
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Below are the most recent publications written about "Reserpine" by people in Profiles.
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Nammi S, Boini KM, Koppula S, Sreemantula S. Reserpine-induced central effects: pharmacological evidence for the lack of central effects of reserpine methiodide. Can J Physiol Pharmacol. 2005 Jun; 83(6):509-15.
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Sreemantula S, Boini KM, Koppula S, Kilari EK, Nammi S. Indirect biochemical evidence that reserpine methiodide produces selective depletion of peripheral biogenic amines in rats. Pharmazie. 2005 Apr; 60(4):294-7.
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Sreemantula S, Boini KM, Nammi S. Reserpine methonitrate, a novel quaternary analogue of reserpine augments urinary excretion of VMA and 5-HIAA without affecting HVA in rats. BMC Pharmacol. 2004 Nov 16; 4:30.
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Bond RA, Clarke DE. A response to isoprenaline unrelated to alpha- and beta-adrenoceptor agonism. Br J Pharmacol. 1987 Jul; 91(3):683-6.
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Lokhandwala MF, Jandhyala BS. The role of sympathetic nervous system in the vascular actions of dopamine. J Pharmacol Exp Ther. 1979 Jul; 210(1):120-6.
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Jandhyala BS, Clarke DE, Buckley JP. Effects of prolonged administration of certain antihypertensive agents. J Pharm Sci. 1974 Oct; 63(10):1497-513.
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Cavero I, Jandhyala BS, Buckley JP. Prolonged effects of reserpine administration on adrenoceptor activity in dogs. J Pharm Pharmacol. 1971 Dec; 23(12):988-9.
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Jandhyala BS, Cavero I, Adams HR, Smookler HH, Dixit BN, Buckley JP. Cardiovascular effects of chronic reserpine administration in mongrel dogs. Eur J Pharmacol. 1971 Nov-Dec; 16(3):261-70.
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Adams HR, Smookler HH, Clarke DE, Jandhyala BS, Dixit BN, Ertel RJ, Buckley JP. Clinicopathologic effects of chronic reserpine administration in mongrel dogs. J Pharm Sci. 1971 Aug; 60(8):1134-8.
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BRUNE GG, PSCHEIDT GR. Correlations between behavior and urinary excretion of indole amines and catecholamines in schizophrenic patients as affected by drugs. Fed Proc. 1961 Dec; 20:889-93.
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