 Macrophage-1 Antigen
"Macrophage-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b ANTIGEN and the beta subunit the CD18 ANTIGEN. The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
| Descriptor ID |
D016177
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| MeSH Number(s) |
D12.776.543.750.705.408.495.500 D12.776.543.750.705.408.600.500 D12.776.543.750.705.833.500
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| Concept/Terms |
Macrophage-1 Antigen- Macrophage-1 Antigen
- Antigen, Macrophage-1
- Macrophage 1 Antigen
- CR3 Receptor
- Receptor, CR3
- Mo1 Antigen Receptor
- Antigen Receptor, Mo1
- Receptor, Mo1 Antigen
- Mo1 Glycoprotein Receptor
- Glycoprotein Receptor, Mo1
- Receptor, Mo1 Glycoprotein
- Integrin alpha(M)beta(2)
- Integrin alpha-M beta-2
- Integrin alpha M beta 2
- alpha-M beta-2, Integrin
- Complement 3 Receptor
- Receptor, Complement 3
- Mac-1 Antigen
- Mac 1 Antigen
- Adhesive Receptor Mac-1
- Mac-1 Adhesive Receptor
- Adhesive Receptor, Mac-1
- Mac 1 Adhesive Receptor
- Receptor, Mac-1 Adhesive
- Mac-1 Receptor
- Mac 1 Receptor
- Integrin alphaMbeta2
- alphaMbeta2, Integrin
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Below are MeSH descriptors whose meaning is more general than "Macrophage-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "Macrophage-1 Antigen".
This graph shows the total number of publications written about "Macrophage-1 Antigen" by people in this website by year, and whether "Macrophage-1 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 1 | 2 | | 1998 | 1 | 1 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage-1 Antigen" by people in Profiles.
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Yin M, Li X, Tan S, Zhou HJ, Ji W, Bellone S, Xu X, Zhang H, Santin AD, Lou G, Min W. Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer. J Clin Invest. 2016 Nov 01; 126(11):4157-4173.
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Eby JC, Gray MC, Mangan AR, Donato GM, Hewlett EL. Role of CD11b/CD18 in the process of intoxication by the adenylate cyclase toxin of Bordetella pertussis. Infect Immun. 2012 Feb; 80(2):850-9.
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Perkins DJ, Gray MC, Hewlett EL, Vogel SN. Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1). Mol Microbiol. 2007 Nov; 66(4):1003-15.
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Kanwar S, Smith CW, Shardonofsky FR, Burns AR. The role of Mac-1 (CD11b/CD18) in antigen-induced airway eosinophilia in mice. Am J Respir Cell Mol Biol. 2001 Aug; 25(2):170-7.
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Gopalan PK, Burns AR, Simon SI, Sparks S, McIntire LV, Smith CW. Preferential sites for stationary adhesion of neutrophils to cytokine-stimulated HUVEC under flow conditions. J Leukoc Biol. 2000 Jul; 68(1):47-57.
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Konstantopoulos K, Neelamegham S, Burns AR, Hentzen E, Kansas GS, Snapp KR, Berg EL, Hellums JD, Smith CW, McIntire LV, Simon SI. Venous levels of shear support neutrophil-platelet adhesion and neutrophil aggregation in blood via P-selectin and beta2-integrin. Circulation. 1998 Sep 01; 98(9):873-82.
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Neelamegham S, Taylor AD, Burns AR, Smith CW, Simon SI. Hydrodynamic shear shows distinct roles for LFA-1 and Mac-1 in neutrophil adhesion to intercellular adhesion molecule-1. Blood. 1998 Sep 01; 92(5):1626-38.
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Hasslen SR, Burns AR, Simon SI, Smith CW, Starr K, Barclay AN, Michie SA, Nelson RD, Erlandsen SL. Preservation of spatial organization and antigenicity of leukocyte surface molecules by aldehyde fixation: flow cytometry and high-resolution FESEM studies of CD62L, CD11b, and Thy-1. J Histochem Cytochem. 1996 Oct; 44(10):1115-22.
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Doré M, Burns AR, Hughes BJ, Entman ML, Smith CW. Chemoattractant-induced changes in surface expression and redistribution of a functional ligand for P-selectin on neutrophils. Blood. 1996 Mar 01; 87(5):2029-37.
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Simon SI, Burns AR, Taylor AD, Gopalan PK, Lynam EB, Sklar LA, Smith CW. L-selectin (CD62L) cross-linking signals neutrophil adhesive functions via the Mac-1 (CD11b/CD18) beta 2-integrin. J Immunol. 1995 Aug 01; 155(3):1502-14.
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