 Interferon-alpha
"Interferon-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells. In addition to antiviral activity, it activates NATURAL KILLER CELLS and B-LYMPHOCYTES, and down-regulates VASCULAR ENDOTHELIAL GROWTH FACTOR expression through PI-3 KINASE and MAPK KINASES signaling pathways.
| Descriptor ID |
D016898
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| MeSH Number(s) |
D12.644.276.374.440.890.250 D12.776.467.374.440.890.250 D23.529.374.440.890.250
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| Concept/Terms |
Interferon-alpha- Interferon-alpha
- Interferon alpha
- Interferon Alfa
- Interferon, Lymphoblastoid
- Lymphoblastoid Interferon
- Interferon, Leukocyte
- Leukocyte Interferon
- Interferon, Lymphoblast
- Lymphoblast Interferon
- alpha-Interferon
- alpha Interferon
- Interferon, alpha
Interferon alpha-17- Interferon alpha-17
- Interferon alpha 17
- Interferon alpha-T
- Interferon alpha T
- LeIF I
- Interferon alpha-88
- Interferon alpha 88
Interferon alpha-7- Interferon alpha-7
- Interferon alpha 7
- LeIF J
- Interferon alpha-J
- Interferon alpha J
Interferon alpha-5- Interferon alpha-5
- Interferon alpha 5
- Interferon alpha5
- IFN-alpha5
- IFN alpha5
Interferon alpha-2- Interferon alpha-2
- Interferon alpha 2
- LeIF A
- Interferon alpha-A
- Interferon alpha A
- Interferon-alpha 2
- 2, Interferon-alpha
- IFN-alpha 2
- IFN-alpha-2
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Below are MeSH descriptors whose meaning is more general than "Interferon-alpha".
Below are MeSH descriptors whose meaning is more specific than "Interferon-alpha".
This graph shows the total number of publications written about "Interferon-alpha" by people in this website by year, and whether "Interferon-alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interferon-alpha" by people in Profiles.
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Cattie JE, Letendre SL, Woods SP, Barakat F, Perry W, Cherner M, Umlauf A, Franklin D, Heaton RK, Hassanein T, Grant I. Persistent neurocognitive decline in a clinic sample of hepatitis C virus-infected persons receiving interferon and ribavirin treatment. J Neurovirol. 2014 Dec; 20(6):561-70.
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Saba NS, George TJ, Boulmay BC. Adjuvant high-dose interferon-{alpha} for resected melanoma in a patient with HIV infection. Oncologist. 2010; 15(7):695-8.
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Dickinson MD, Barr CD, Hiscock M, Meyers CA. Cognitive effects of pegylated interferon in individuals with primary brain tumors. J Neurooncol. 2009 Nov; 95(2):231-237.
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