 Seminoma
"Seminoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)
| Descriptor ID |
D018239
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| MeSH Number(s) |
C04.557.465.330.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Seminoma".
Below are MeSH descriptors whose meaning is more specific than "Seminoma".
This graph shows the total number of publications written about "Seminoma" by people in this website by year, and whether "Seminoma" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "Seminoma" by people in Profiles.
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Kukoski R, Blonigen B, Macri E, Renshaw AA, Hoffman M, Loda M, Datta MW. p27 and cyclin E/D2 associations in testicular germ cell tumors: implications for tumorigenesis. Appl Immunohistochem Mol Morphol. 2003 Jun; 11(2):138-43.
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Datta MW, Macri E, Signoretti S, Renshaw AA, Loda M. Transition from in situ to invasive testicular germ cell neoplasia is associated with the loss of p21 and gain of mdm-2 expression. Mod Pathol. 2001 May; 14(5):437-42.
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Dry SM, Renshaw AA. Extratesticular extension of germ cell tumors preferentially occurs at the hilum. Am J Clin Pathol. 1999 Apr; 111(4):534-8.
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Olumi AF, Garnick MB, Renshaw AA, Benson CA, Richie JP. Leydig cell hyperplasia mimicking testicular neoplasm. Urology. 1996 Oct; 48(4):647-9.
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