Neuregulin-1
"Neuregulin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide factor originally identified by its ability to stimulate the phosphorylation the erbB-2 receptor (RECEPTOR, ERBB-2). It is a ligand for the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Variant forms of NEUREGULIN-1 occur through alternative splicing of its mRNA.
Descriptor ID |
D020890
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MeSH Number(s) |
D12.644.276.860.550.750 D12.776.467.860.550.750 D12.776.641.600.550.750 D23.529.850.550.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neuregulin-1".
Below are MeSH descriptors whose meaning is more specific than "Neuregulin-1".
This graph shows the total number of publications written about "Neuregulin-1" by people in this website by year, and whether "Neuregulin-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2004 | 0 | 1 | 1 |
2005 | 2 | 0 | 2 |
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Below are the most recent publications written about "Neuregulin-1" by people in Profiles.
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Chae KS, Dryer SE. Regulation of neuronal K(Ca) channels by beta-neuregulin-1 does not require activation of Ras-MEK-extracellular signal-regulated kinase signaling cascades. Neuroscience. 2005; 135(4):1013-6.
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Chae KS, Oh KS, Dryer SE. Growth factors mobilize multiple pools of KCa channels in developing parasympathetic neurons: role of ADP-ribosylation factors and related proteins. J Neurophysiol. 2005 Aug; 94(2):1597-605.
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Chae KS, Martin-Caraballo M, Anderson M, Dryer SE. Akt activation is necessary for growth factor-induced trafficking of functional K(Ca) channels in developing parasympathetic neurons. J Neurophysiol. 2005 Mar; 93(3):1174-82.
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Cameron JS, Dryer L, Dryer SE. beta -Neuregulin-1 is required for the in vivo development of functional Ca2+-activated K+ channels in parasympathetic neurons. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2832-6.
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Sandrock AW, Dryer SE, Rosen KM, Gozani SN, Kramer R, Theill LE, Fischbach GD. Maintenance of acetylcholine receptor number by neuregulins at the neuromuscular junction in vivo. Science. 1997 Apr 25; 276(5312):599-603.