 Steven Bark
| Title | Assistant Professor |
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| Institution | University of Houston |
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| Department | Biology |
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| Address | 4800 Calhoun Rd
Houston TX 77004
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| Phone | 713-743-9638 |
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| vCard | Download vCard |
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 Research K01DA023065 (BARK, STEVEN)Apr 1, 2008 - Dec 31, 2013 NIH/NIDA
Cathepsin L in the Biosynthesis of Enkephalins and beta-Endorphin Opioid Peptides
Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Mali S, Mitchell M, Havis S, Bodunrin A, Rangel J, Olson G, Widger WR, Bark SJ. A Proteomic Signature of Dormancy in the Actinobacterium Micrococcus luteus. J Bacteriol. 2017 Jul 15; 199(14). PMID: 28484042.
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Mali S, Moree WJ, Mitchell M, Widger W, Bark SJ. Observations on different resin strategies for affinity purification mass spectrometry of a tagged protein. Anal Biochem. 2016 Dec 15; 515:26-32. PMID: 27693234.
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Li S, Cai H, He J, Chen H, Lam S, Cai T, Zhu Z, Bark SJ, Cai C. Extent of the Oxidative Side Reactions to Peptides and Proteins During the CuAAC Reaction. Bioconjug Chem. 2016 Oct 19; 27(10):2315-2322. PMID: 27583984.
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Yang L, Moghaddas S, Dezvareh H, Belkacemi L, Bark SJ, Bose RN, Do LH. Insights into the anti-angiogenic properties of phosphaplatins. J Inorg Biochem. 2016 Nov; 164:5-16. PMID: 27591123.
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Vollert CT, Moree WJ, Gregory S, Bark SJ, Eriksen JL. Formaldehyde scavengers function as novel antigen retrieval agents. Sci Rep. 2015 Nov 27; 5:17322. PMID: 26612041; PMCID: PMC4661444.
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Mitchell M, Mali S, King CC, Bark SJ. Enhancing MALDI time-of-flight mass spectrometer performance through spectrum averaging. PLoS One. 2015; 10(3):e0120932. PMID: 25798583; PMCID: PMC4370844.
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Bark SJ, Wegrzyn J, Taupenot L, Ziegler M, O'Connor DT, Ma Q, Smoot M, Ideker T, Hook V. The protein architecture of human secretory vesicles reveals differential regulation of signaling molecule secretion by protein kinases. PLoS One. 2012; 7(8):e41134. PMID: 22916103; PMCID: PMC3420874.
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Hook V, Funkelstein L, Wegrzyn J, Bark S, Kindy M, Hook G. Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease. Biochim Biophys Acta. 2012 Jan; 1824(1):89-104. PMID: 21925292; PMCID: PMC3232284.
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Kim Y, Bark S, Hook V, Bandeira N. NeuroPedia: neuropeptide database and spectral library. Bioinformatics. 2011 Oct 01; 27(19):2772-3. PMID: 21821666; PMCID: PMC3179654.
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Gupta N, Bark SJ, Lu WD, Taupenot L, O'Connor DT, Pevzner P, Hook V. Mass spectrometry-based neuropeptidomics of secretory vesicles from human adrenal medullary pheochromocytoma reveals novel peptide products of prohormone processing. J Proteome Res. 2010 Oct 01; 9(10):5065-75. PMID: 20704348; PMCID: PMC3000314.
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Wegrzyn JL, Bark SJ, Funkelstein L, Mosier C, Yap A, Kazemi-Esfarjani P, La Spada AR, Sigurdson C, O'Connor DT, Hook V. Proteomics of dense core secretory vesicles reveal distinct protein categories for secretion of neuroeffectors for cell-cell communication. J Proteome Res. 2010 Oct 01; 9(10):5002-24. PMID: 20695487; PMCID: PMC2996463.
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Hook V, Bark S, Gupta N, Lortie M, Lu WD, Bandeira N, Funkelstein L, Wegrzyn J, O'Connor DT, Pevzner P. Neuropeptidomic components generated by proteomic functions in secretory vesicles for cell-cell communication. AAPS J. 2010 Dec; 12(4):635-45. PMID: 20734175; PMCID: PMC2976990.
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Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE, Bark S, Dorrestein PC. Expansion of the mycobacterial "PUPylome". Mol Biosyst. 2010 Feb; 6(2):376-85. PMID: 20094657; PMCID: PMC2846642.
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Lortie M, Bark S, Blantz R, Hook V. Detecting low-abundance vasoactive peptides in plasma: progress toward absolute quantitation using nano liquid chromatography-mass spectrometry. Anal Biochem. 2009 Nov 15; 394(2):164-70. PMID: 19615967; PMCID: PMC2745394.
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Bark SJ, Lu WD, Hook V. Linear and accurate quantitation of proenkephalin-derived peptides by isotopic labeling with internal standards and mass spectrometry. Anal Biochem. 2009 Jun 01; 389(1):18-26. PMID: 19289094; PMCID: PMC2731681.
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Hook V, Funkelstein L, Lu D, Bark S, Wegrzyn J, Hwang SR. Proteases for processing proneuropeptides into peptide neurotransmitters and hormones. Annu Rev Pharmacol Toxicol. 2008; 48:393-423. PMID: 18184105; PMCID: PMC2731677.
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Bark SJ, Hook V. Differential recovery of peptides from sample tubes and the reproducibility of quantitative proteomic data. J Proteome Res. 2007 Nov; 6(11):4511-6. PMID: 17850064.
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Hwang SR, O'Neill A, Bark S, Foulon T, Hook V. Secretory vesicle aminopeptidase B related to neuropeptide processing: molecular identification and subcellular localization to enkephalin- and NPY-containing chromaffin granules. J Neurochem. 2007 Mar; 100(5):1340-50. PMID: 17241125.
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Bark SJ, Hook V. The future of proteomic analysis in biological systems and molecular medicine. Mol Biosyst. 2007 Jan; 3(1):14-7. PMID: 17216050.
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Saphire AC, Gallay PA, Bark SJ. Proteomic analysis of human immunodeficiency virus using liquid chromatography/tandem mass spectrometry effectively distinguishes specific incorporated host proteins. J Proteome Res. 2006 Mar; 5(3):530-8. PMID: 16512667.
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Trauger SA, Wu E, Bark SJ, Nemerow GR, Siuzdak G. The identification of an adenovirus receptor by using affinity capture and mass spectrometry. Chembiochem. 2004 Aug 06; 5(8):1095-9. PMID: 15300833.
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Bark SJ, Muster N, Yates JR, Siuzdak G. High-temperature protein mass mapping using a thermophilic protease. J Am Chem Soc. 2001 Feb 28; 123(8):1774-5. PMID: 11456785.
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Bark SJ, Kent SB. Engineering an unnatural Nalpha-anchored disulfide into BPTI by total chemical synthesis: structural and functional consequences. FEBS Lett. 1999 Oct 22; 460(1):67-76. PMID: 10571063.
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Saphire AC, Bark SJ, Gerace L. All four homochiral enantiomers of a nuclear localization sequence derived from c-Myc serve as functional import signals. J Biol Chem. 1998 Nov 06; 273(45):29764-9. PMID: 9792690.
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| Year | Publications |
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| 1998 | 1 | | 1999 | 1 | | 2001 | 1 | | 2004 | 1 | | 2006 | 2 | | 2007 | 2 | | 2008 | 1 | | 2009 | 3 | | 2010 | 3 | | 2011 | 2 | | 2012 | 1 | | 2015 | 2 | | 2016 | 3 | | 2017 | 1 |
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