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Deborah Otteson

TitleAssociate Professor
InstitutionUniversity of Houston
DepartmentDean, Optometry
Address4800 Calhoun Rd
Houston TX 77004
Phone713-743-1952
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    Collapse Research 
    Collapse research activities and funding
    F32EY013499     (OTTESON, DEBORAH C)Mar 16, 2001
    NIH/NEI
    Regulation of Rhodopsin Expression: The Role of RKLF
    Role: Principal Investigator

    R01EY021792     (OTTESON, DEBORAH C)Sep 1, 2011 - Aug 31, 2016
    NIH/NEI
    Regulation of Ephrin Receptor Expression in the Retina
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Manarang JC, Otteson DC, McDermott AM. Expression of Antimicrobial Peptides by Uveal and Cutaneous Melanoma Cells and Investigation of Their Role in Tumor Cell Migration and Vasculogenic Mimicry. Curr Eye Res. 2017 Sep 14; 1-8. PMID: 28910167.
      View in: PubMed
    2. Otteson DC. Talkin' about my (re)generation: The who of intrinsic retinal stem cells. Neuroscience. 2017 Mar 27; 346:447-449. PMID: 28131621.
      View in: PubMed
    3. Beach KM, Wang J, Otteson DC. Regulation of Stem Cell Properties of Müller Glia by JAK/STAT and MAPK Signaling in the Mammalian Retina. Stem Cells Int. 2017; 2017:1610691. PMID: 28194183.
      View in: PubMed
    4. Wang J, Galvao J, Beach KM, Luo W, Urrutia RA, Goldberg JL, Otteson DC. Novel roles and mechanism for Krüppel-like factor 16 (KLF16) regulation of neurite outgrowth and ephrin receptor A5 (EphA5) expression in retinal ganglion cells. J Biol Chem. 2016 Oct 07; 291(41):21422. PMID: 27825077.
      View in: PubMed
    5. Wang J, Galvao J, Beach KM, Luo W, Urrutia RA, Goldberg JL, Otteson DC. Novel Roles and Mechanism for Krüppel-like Factor 16 (KLF16) Regulation of Neurite Outgrowth and Ephrin Receptor A5 (EphA5) Expression in Retinal Ganglion Cells. J Biol Chem. 2016 Aug 26; 291(35):18084-95. PMID: 27402841; PMCID: PMC5000058 [Available on 08/26/17].
    6. Adhikari AR, Geranpayeh T, Chu WK, Otteson DC. Improved cellular response of ion modified poly(lactic acid-co-glycolic acid) substrates for mouse fibroblast cells. Mater Sci Eng C Mater Biol Appl. 2016 Mar; 60:151-155. PMID: 26706518.
      View in: PubMed
    7. Tiwari S, Dharmarajan S, Shivanna M, Otteson DC, Belecky-Adams TL. Histone deacetylase expression patterns in developing murine optic nerve. BMC Dev Biol. 2014 Jul 09; 14:30. PMID: 25011550; PMCID: PMC4099093.
    8. Kiyama T, Li H, Gupta M, Lin YP, Chuang AZ, Otteson DC, Wang SW. Distinct neurogenic potential in the retinal margin and the pars plana of mammalian eye. J Neurosci. 2012 Sep 12; 32(37):12797-807. PMID: 22973003; PMCID: PMC3462447.
    9. Davis JT, Wen Q, Janmey PA, Otteson DC, Foster WJ. Muller cell expression of genes implicated in proliferative vitreoretinopathy is influenced by substrate elastic modulus. Invest Ophthalmol Vis Sci. 2012 May 17; 53(6):3014-9. PMID: 22447866; PMCID: PMC3378084.
    10. Otteson DC. Eyes on DNA methylation: current evidence for DNA methylation in ocular development and disease. J Ocul Biol Dis Infor. 2011 Sep; 4(3):95-103. PMID: 23538551; PMCID: PMC3382291.
    11. Phillips MJ, Otteson DC. Differential expression of neuronal genes in Müller glia in two- and three-dimensional cultures. Invest Ophthalmol Vis Sci. 2011 Mar; 52(3):1439-49. PMID: 21051699; PMCID: PMC3101681.
    12. Petkova TD, Seigel GM, Otteson DC. A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina. Vision Res. 2011 Jan 28; 51(2):260-8. PMID: 20875442; PMCID: PMC3024446.
    13. Phillips MJ, Otteson DC, Sherry DM. Progression of neuronal and synaptic remodeling in the rd10 mouse model of retinitis pigmentosa. J Comp Neurol. 2010 Jun 01; 518(11):2071-89. PMID: 20394059; PMCID: PMC2881548.
    14. Otteson DC, Phillips MJ. A conditional immortalized mouse muller glial cell line expressing glial and retinal stem cell genes. Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5991-6000. PMID: 20505190; PMCID: PMC3061519.
    15. Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Mol Cell Biol. 2010 Apr; 30(8):1866-77. PMID: 20123965; PMCID: PMC2849472.
    16. Wang MH, Frishman LJ, Otteson DC. Intracellular delivery of proteins into mouse Müller glia cells in vitro and in vivo using Pep-1 transfection reagent. J Neurosci Methods. 2009 Mar 15; 177(2):403-19. PMID: 19056421; PMCID: PMC2681185.
    17. Mojumder DK, Frishman LJ, Otteson DC, Sherry DM. Voltage-gated sodium channel alpha-subunits Na(v)1.1, Na(v)1.2, and Na(v)1.6 in the distal mammalian retina. Mol Vis. 2007 Nov 27; 13:2163-82. PMID: 18079688.
      View in: PubMed
    18. Otteson DC, Tsujikawa M, Gunatilaka T, Malicki J, Zack DJ. Genomic organization of zebrafish cone-rod homeobox gene and exclusion as a candidate gene for retinal degeneration in niezerka and mikre oko. Mol Vis. 2005 Nov 17; 11:986-95. PMID: 16319818; PMCID: PMC2879142.
    19. Kerrison JB, Duh EJ, Yu Y, Otteson DC, Zack DJ. A system for inducible gene expression in retinal ganglion cells. Invest Ophthalmol Vis Sci. 2005 Aug; 46(8):2932-9. PMID: 16043868.
      View in: PubMed
    20. Otteson DC, Lai H, Liu Y, Zack DJ. Zinc-finger domains of the transcriptional repressor KLF15 bind multiple sites in rhodopsin and IRBP promoters including the CRS-1 and G-rich repressor elements. BMC Mol Biol. 2005 Jun 17; 6:15. PMID: 15963234; PMCID: PMC1182371.
    21. Kerrison JB, Lewis RN, Otteson DC, Zack DJ. Bone morphogenetic proteins promote neurite outgrowth in retinal ganglion cells. Mol Vis. 2005 Mar 18; 11:208-15. PMID: 15788999.
      View in: PubMed
    22. Hackam AS, Strom R, Liu D, Qian J, Wang C, Otteson D, Gunatilaka T, Farkas RH, Chowers I, Kageyama M, Leveillard T, Sahel JA, Campochiaro PA, Parmigiani G, Zack DJ. Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):2929-42. PMID: 15326104.
      View in: PubMed
    23. Otteson DC, Liu Y, Lai H, Wang C, Gray S, Jain MK, Zack DJ. Kruppel-like factor 15, a zinc-finger transcriptional regulator, represses the rhodopsin and interphotoreceptor retinoid-binding protein promoters. Invest Ophthalmol Vis Sci. 2004 Aug; 45(8):2522-30. PMID: 15277472; PMCID: PMC2660604.
    24. Farkas RH, Chowers I, Hackam AS, Kageyama M, Nickells RW, Otteson DC, Duh EJ, Wang C, Valenta DF, Gunatilaka TL, Pease ME, Quigley HA, Zack DJ. Increased expression of iron-regulating genes in monkey and human glaucoma. Invest Ophthalmol Vis Sci. 2004 May; 45(5):1410-7. PMID: 15111596.
      View in: PubMed
    25. Hitchcock P, Ochocinska M, Sieh A, Otteson D. Persistent and injury-induced neurogenesis in the vertebrate retina. Prog Retin Eye Res. 2004 Mar; 23(2):183-94. PMID: 15094130.
      View in: PubMed
    26. Otteson DC, Hitchcock PF. Stem cells in the teleost retina: persistent neurogenesis and injury-induced regeneration. Vision Res. 2003 Apr; 43(8):927-36. PMID: 12668062.
      View in: PubMed
    27. Otteson DC, Cirenza PF, Hitchcock PF. Persistent neurogenesis in the teleost retina: evidence for regulation by the growth-hormone/insulin-like growth factor-I axis. Mech Dev. 2002 Sep; 117(1-2):137-49. PMID: 12204254.
      View in: PubMed
    28. Hitchcock PF, Otteson DC, Cirenza PF. Expression of the insulin receptor in the retina of the goldfish. Invest Ophthalmol Vis Sci. 2001 Aug; 42(9):2125-9. PMID: 11481281.
      View in: PubMed
    29. Otteson DC, D'Costa AR, Hitchcock PF. Putative stem cells and the lineage of rod photoreceptors in the mature retina of the goldfish. Dev Biol. 2001 Apr 01; 232(1):62-76. PMID: 11254348.
      View in: PubMed
    30. Otteson DC, Shelden E, Jones JM, Kameoka J, Hitchcock PF. Pax2 expression and retinal morphogenesis in the normal and Krd mouse. Dev Biol. 1998 Jan 15; 193(2):209-24. PMID: 9473325.
      View in: PubMed
    31. Pattatucci AM, Otteson DC, Kaufman TC. A functional and structural analysis of the Sex combs reduced locus of Drosophila melanogaster. Genetics. 1991 Oct; 129(2):423-41. PMID: 1743486; PMCID: PMC1204634.
    32. Underwood EM, Briot AS, Doll KZ, Ludwiczak RL, Otteson DC, Tower J, Vessey KB, Yu K. Genetics of 51D-52A, a region containing several maternal-effect genes and two maternal-specific transcripts in Drosophila. Genetics. 1990 Nov; 126(3):639-50. PMID: 2249762; PMCID: PMC1204219.
    33. Cavener DR, Otteson DC, Kaufman TC. A rehabilitation of the genetic map of the 84B-D region in Drosophila melanogaster. Genetics. 1986 Sep; 114(1):111-23. PMID: 3095179; PMCID: PMC1202924.
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