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James Schafer

TitleAssociate Professor
InstitutionUniversity of Houston
DepartmentHistory
Address4800 Calhoun Rd
Houston TX 77004
Phone713-743-3119
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    R01AM025519     (SCHAFER, JAMES A)Jun 1, 1979 - May 31, 1989
    NIH/NIADDK
    RENAL TRANSPORT OF NONELECTROLYTES, SALT, AND WATER
    Role: Principal Investigator

    R01DK025519     (SCHAFER, JAMES A)Jun 1, 1979 - Dec 31, 2003
    NIH/NIDDK
    RENAL TRANSPORT OF NONELECTROLYTES, SALT AND WATER
    Role: Principal Investigator

    R01DK045768     (SCHAFER, JAMES A)Aug 1, 1993 - Jul 31, 1998
    NIH/NIDDK
    REGULATION OF NA/CL TRANSPORT IN DAHL/RAPP RAT NEPHRONS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Schafer JA. Fighting for business: the limits of professional cooperation among American doctors during the First World War. J Hist Med Allied Sci. 2015 Apr; 70(2):165-94. PMID: 24497615.
      View in: PubMed
    2. Xie Y, Schafer JA. Endogenous ATP release inhibits electrogenic Na? absorption and stimulates Cl? secretion in MDCK cells. Purinergic Signal. 2008 Jun; 4(2):125-37. PMID: 18368527; PMCID: PMC2377323.
    3. Schafer JA. Experimental validation of the countercurrent model of urinary concentration. Am J Physiol Renal Physiol. 2004 Nov; 287(5):F861-3. PMID: 15475537.
      View in: PubMed
    4. Schafer JA. Renal water reabsorption: a physiologic retrospective in a molecular era. Kidney Int Suppl. 2004 Oct; (91):S20-7. PMID: 15461698.
      View in: PubMed
    5. Xie Y, Schafer JA. Inhibition of ENaC by intracellular Cl- in an MDCK clone with high ENaC expression. Am J Physiol Renal Physiol. 2004 Oct; 287(4):F722-31. PMID: 15161604.
      View in: PubMed
    6. Schafer JA. Abnormal regulation of ENaC: syndromes of salt retention and salt wasting by the collecting duct. Am J Physiol Renal Physiol. 2002 Aug; 283(2):F221-35. PMID: 12110505.
      View in: PubMed
    7. Morris RG, Schafer JA. cAMP increases density of ENaC subunits in the apical membrane of MDCK cells in direct proportion to amiloride-sensitive Na(+) transport. J Gen Physiol. 2002 Jul; 120(1):71-85. PMID: 12084777; PMCID: PMC2311399.
    8. Yoder BK, Tousson A, Millican L, Wu JH, Bugg CE, Schafer JA, Balkovetz DF. Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium. Am J Physiol Renal Physiol. 2002 Mar; 282(3):F541-52. PMID: 11832437.
      View in: PubMed
    9. Schafer JA. Interaction of modeling and experimental approaches to understanding renal salt and water balance. Ann Biomed Eng. 2000 Aug; 28(8):1002-9. PMID: 11144661.
      View in: PubMed
    10. Schafer JA, Patlak CS, Andreoli TE. Fluid absorption and active and passive ion flows in the rabbit superficial pars recta. J Am Soc Nephrol. 2000 Apr; 11(4):784-800. PMID: 10752539.
      View in: PubMed
    11. Schafer JA, Li L, Sun D. The collecting duct, dopamine and vasopressin-dependent hypertension. Acta Physiol Scand. 2000 Jan; 168(1):239-44. PMID: 10691807.
      View in: PubMed
    12. Sun D, Wilborn TW, Schafer JA. Dopamine D4 receptor isoform mRNA and protein are expressed in the rat cortical collecting duct. Am J Physiol. 1998 Nov; 275(5 Pt 2):F742-51. PMID: 9815131.
      View in: PubMed
    13. Schafer JA, Chen L. Low Na+ diet inhibits Na+ and water transport response to vasopressin in rat cortical collecting duct. Kidney Int. 1998 Jul; 54(1):180-7. PMID: 9648077.
      View in: PubMed
    14. Li L, Schafer JA. Dopamine inhibits vasopressin-dependent cAMP production in the rat cortical collecting duct. Am J Physiol. 1998 Jul; 275(1 Pt 2):F62-7. PMID: 9689005.
      View in: PubMed
    15. Wilborn TW, Sun D, Schafer JA. Expression of multiple alpha-adrenoceptor isoforms in rat CCD. Am J Physiol. 1998 Jul; 275(1 Pt 2):F111-8. PMID: 9689012.
      View in: PubMed
    16. Morris RG, Tousson A, Benos DJ, Schafer JA. Microtubule disruption inhibits AVT-stimulated Cl- secretion but not Na+ reabsorption in A6 cells. Am J Physiol. 1998 Feb; 274(2 Pt 2):F300-14. PMID: 9486225.
      View in: PubMed
    17. Schafer JA, Watkins ML, Li L, Herter P, Haxelmans S, Schlatter E. A simplified method for isolation of large numbers of defined nephron segments. Am J Physiol. 1997 Oct; 273(4 Pt 2):F650-7. PMID: 9362342.
      View in: PubMed
    18. Hawk CT, Li L, Schafer JA. AVP and aldosterone at physiological concentrations have synergistic effects on Na+ transport in rat CCD. Kidney Int Suppl. 1996 Dec; 57:S35-41. PMID: 8941920.
      View in: PubMed
    19. Sun D, Schafer JA. Dopamine inhibits AVP-dependent Na+ transport and water permeability in rat CCD via a D4-like receptor. Am J Physiol. 1996 Aug; 271(2 Pt 2):F391-400. PMID: 8770171.
      View in: PubMed
    20. Wilborn TW, Schafer JA. Differential expression of PKC isoforms in fresh and cultured rabbit CCD. Am J Physiol. 1996 May; 270(5 Pt 2):F766-75. PMID: 8928837.
      View in: PubMed
    21. Kudo LH, Hawk CT, Schafer JA. Sodium and water transport in cortical collecting duct of Dahl salt-resistant rat. Am J Physiol. 1994 Oct; 267(4 Pt 2):F583-91. PMID: 7943356.
      View in: PubMed
    22. Schafer JA. 1993 Homer W. Smith Award. Salt and water homeostasis--is it just a matter of good bookkeeping? J Am Soc Nephrol. 1994 Jun; 4(12):1929-50. PMID: 7919147.
      View in: PubMed
    23. Rouch AJ, Chen L, Kudo LH, Bell PD, Fowler BC, Corbitt BD, Schafer JA. Intracellular Ca2+ and PKC activation do not inhibit Na+ and water transport in rat CCD. Am J Physiol. 1993 Oct; 265(4 Pt 2):F569-77. PMID: 8238386.
      View in: PubMed
    24. Hawk CT, Kudo LH, Rouch AJ, Schafer JA. Inhibition by epinephrine of AVP- and cAMP-stimulated Na+ and water transport in Dahl rat CCD. Am J Physiol. 1993 Sep; 265(3 Pt 2):F449-60. PMID: 8105698.
      View in: PubMed
    25. Canessa CM, Schafer JA. AVP stimulates Na+ transport in primary cultures of rabbit cortical collecting duct cells. Am J Physiol. 1992 Mar; 262(3 Pt 2):F454-61. PMID: 1558162.
      View in: PubMed
    26. Schafer JA, Hawk CT. Regulation of Na+ channels in the cortical collecting duct by AVP and mineralocorticoids. Kidney Int. 1992 Feb; 41(2):255-68. PMID: 1313121.
      View in: PubMed
    27. Chen L, Reif MC, Schafer JA. Clonidine and PGE2 have different effects on Na+ and water transport in rat and rabbit CCD. Am J Physiol. 1991 Jul; 261(1 Pt 2):F126-36. PMID: 1858893.
      View in: PubMed
    28. Hawk CT, Schafer JA. Effects of AVP and deoxycorticosterone on Na+ and water transport in the Dahl salt-sensitive rat CCD. Am J Physiol. 1991 Apr; 260(4 Pt 2):F471-8. PMID: 1849360.
      View in: PubMed
    29. Rouch AJ, Chen L, Troutman SL, Schafer JA. Na+ transport in isolated rat CCD: effects of bradykinin, ANP, clonidine, and hydrochlorothiazide. Am J Physiol. 1991 Jan; 260(1 Pt 2):F86-95. PMID: 1847013.
      View in: PubMed
    30. Schafer JA, Troutman SL. cAMP mediates the increase in apical membrane Na+ conductance produced in rat CCD by vasopressin. Am J Physiol. 1990 Nov; 259(5 Pt 2):F823-31. PMID: 1700630.
      View in: PubMed
    31. Chen L, Williams SK, Schafer JA. Differences in synergistic actions of vasopressin and deoxycorticosterone in rat and rabbit CCD. Am J Physiol. 1990 Jul; 259(1 Pt 2):F147-56. PMID: 2375388.
      View in: PubMed
    32. Schafer JA. Transepithelial osmolality differences, hydraulic conductivities, and volume absorption in the proximal tubule. Annu Rev Physiol. 1990; 52:709-26. PMID: 2184773.
      View in: PubMed
    33. Schafer JA, Troutman SL, Schlatter E. Vasopressin and mineralocorticoid increase apical membrane driving force for K+ secretion in rat CCD. Am J Physiol. 1990 Jan; 258(1 Pt 2):F199-210. PMID: 2301591.
      View in: PubMed
    34. Bindels RJ, Schafer JA, Reif MC. Stimulation of sodium transport by aldosterone and arginine vasotocin in A6 cells. Biochim Biophys Acta. 1988 Dec 09; 972(3):320-30. PMID: 3196765.
      View in: PubMed
    35. Schlatter E, Schafer JA. Electrophysiological studies in principal cells of rat cortical collecting tubules. ADH increases the apical membrane Na+-conductance. Pflugers Arch. 1987 Jun; 409(1-2):81-92. PMID: 2441357.
      View in: PubMed
    36. Reif MC, Troutman SL, Schafer JA. Sodium transport by rat cortical collecting tubule. Effects of vasopressin and desoxycorticosterone. J Clin Invest. 1986 Apr; 77(4):1291-8. PMID: 2420830; PMCID: PMC424479.
    37. Schafer JA, Andreoli TE. Rheogenic and passive Na+ absorption by the proximal nephron. Annu Rev Physiol. 1979; 41:211-27. PMID: 373589.
      View in: PubMed
    38. Schafer JA, Patlak CS, Andreoli TE. A component of fluid absorption linked to passive ion flows in the superficial pars recta. J Gen Physiol. 1975 Oct; 66(4):445-71. PMID: 1181377; PMCID: PMC2226218.
    39. Schafer JA, Troutman SL, Andreoli TE. Osmosis in cortical collecting tubules. ADH-independent osmotic flow rectification. J Gen Physiol. 1974 Aug; 64(2):228-40. PMID: 4846768; PMCID: PMC2226168.
    40. Schafer JA, Patlak CS, Andreoli TE. Osmosis in cortical collecting tubules. A theoretical and experimental analysis of the osmotic transient phenomenon. J Gen Physiol. 1974 Aug; 64(2):201-27. PMID: 4846767; PMCID: PMC2226170.
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