Cleft Lip
"Cleft Lip" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region.
Descriptor ID |
D002971
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MeSH Number(s) |
C07.465.409.225 C07.465.525.164 C07.650.525.164 C16.131.850.525.164
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Concept/Terms |
Cleft Lip- Cleft Lip
- Cleft Lips
- Lip, Cleft
- Lips, Cleft
- Harelip
- Harelips
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Below are MeSH descriptors whose meaning is more general than "Cleft Lip".
Below are MeSH descriptors whose meaning is more specific than "Cleft Lip".
This graph shows the total number of publications written about "Cleft Lip" by people in this website by year, and whether "Cleft Lip" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1990 | 1 | 0 | 1 | 2001 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 | 2011 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cleft Lip" by people in Profiles.
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Wang J, Bai Y, Li H, Greene SB, Klysik E, Yu W, Schwartz RJ, Williams TJ, Martin JF. MicroRNA-17-92, a direct Ap-2a transcriptional target, modulates T-box factor activity in orofacial clefting. PLoS Genet. 2013; 9(9):e1003785.
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Wang J, Chen L, Wen S, Zhu H, Yu W, Moskowitz IP, Shaw GM, Finnell RH, Schwartz RJ. Defective sumoylation pathway directs congenital heart disease. Birth Defects Res A Clin Mol Teratol. 2011 Jun; 91(6):468-76.
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Fete M, vanBokhoven H, Clements SE, McKeon F, Roop DR, Koster MI, Missero C, Attardi LD, Lombillo VA, Ratovitski E, Julapalli M, Ruths D, Sybert VP, Siegfried EC, Bree AF. International Research Symposium on Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate (AEC) syndrome. Am J Med Genet A. 2009 Sep; 149A(9):1885-93.
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McGrath JA, Duijf PH, Doetsch V, Irvine AD, de Waal R, Vanmolkot KR, Wessagowit V, Kelly A, Atherton DJ, Griffiths WA, Orlow SJ, van Haeringen A, Ausems MG, Yang A, McKeon F, Bamshad MA, Brunner HG, Hamel BC, van Bokhoven H. Hay-Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63. Hum Mol Genet. 2001 Feb 01; 10(3):221-9.
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Siegel MI, Mooney MP, Eichberg JW, Gest T, Lee DR. Septopremaxillary ligament resection and midfacial growth in a chimpanzee animal model. J Craniofac Surg. 1990 Oct; 1(4):182-6.
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