Extracellular Matrix
"Extracellular Matrix" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A meshwork-like substance found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere.
Descriptor ID |
D005109
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MeSH Number(s) |
A11.284.295.310
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Concept/Terms |
Extracellular Matrix- Extracellular Matrix
- Matrix, Extracellular
- Extracellular Matrices
- Matrices, Extracellular
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Below are MeSH descriptors whose meaning is more general than "Extracellular Matrix".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Matrix".
This graph shows the total number of publications written about "Extracellular Matrix" by people in this website by year, and whether "Extracellular Matrix" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1992 | 1 | 0 | 1 | 2001 | 1 | 0 | 1 | 2003 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2010 | 2 | 2 | 4 | 2011 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2013 | 1 | 1 | 2 | 2014 | 0 | 1 | 1 | 2015 | 2 | 1 | 3 | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Extracellular Matrix" by people in Profiles.
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Chen Y, Guo H, Terajima M, Banerjee P, Liu X, Yu J, Momin AA, Katayama H, Hanash SM, Burns AR, Fields GB, Yamauchi M, Kurie JM. Lysyl Hydroxylase 2 Is Secreted by Tumor Cells and Can Modify Collagen in the Extracellular Space. J Biol Chem. 2016 Dec 09; 291(50):25799-25808.
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Coulson-Thomas VJ. The role of heparan sulphate in development: the ectodermal story. Int J Exp Pathol. 2016 Jun; 97(3):213-29.
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Smith SD, Choudhury RH, Matos P, Horn JA, Lye SJ, Dunk CE, Aplin JD, Jones RL, Harris LK. Changes in vascular extracellular matrix composition during decidual spiral arteriole remodeling in early human pregnancy. Histol Histopathol. 2016 May; 31(5):557-71.
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Al-Ubaidi M, Petroll M. Introduction to Special Issue on ocular ECM. Exp Eye Res. 2015 Apr; 133:1-2.
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Chen Y, Terajima M, Yang Y, Sun L, Ahn YH, Pankova D, Puperi DS, Watanabe T, Kim MP, Blackmon SH, Rodriguez J, Liu H, Behrens C, Wistuba II, Minelli R, Scott KL, Sanchez-Adams J, Guilak F, Pati D, Thilaganathan N, Burns AR, Creighton CJ, Martinez ED, Zal T, Grande-Allen KJ, Yamauchi M, Kurie JM. Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. J Clin Invest. 2015 Mar 02; 125(3):1147-62.
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Bloodworth NC, West JD, Merryman WD. Microvessel mechanobiology in pulmonary arterial hypertension: cause and effect. Hypertension. 2015 Mar; 65(3):483-9.
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Al-Ubaidi MR, Naash MI, Conley SM. A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders. Invest Ophthalmol Vis Sci. 2013 Dec 17; 54(13):8119-24.
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Greening DW, Ji H, Kapp EA, Simpson RJ. Sulindac modulates secreted protein expression from LIM1215 colon carcinoma cells prior to apoptosis. Biochim Biophys Acta. 2013 Nov; 1834(11):2293-307.
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Davis JT, Wen Q, Janmey PA, Otteson DC, Foster WJ. Muller cell expression of genes implicated in proliferative vitreoretinopathy is influenced by substrate elastic modulus. Invest Ophthalmol Vis Sci. 2012 May 17; 53(6):3014-9.
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Coulson-Thomas VJ, Coulson-Thomas YM, Gesteira TF, de Paula CA, Mader AM, Waisberg J, Pinhal MA, Friedl A, Toma L, Nader HB. Colorectal cancer desmoplastic reaction up-regulates collagen synthesis and restricts cancer cell invasion. Cell Tissue Res. 2011 Nov; 346(2):223-36.
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