 Cyclic GMP
"Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
| Descriptor ID |
D006152
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| MeSH Number(s) |
D03.438.759.646.454.160 D13.695.462.275 D13.695.667.454.160 D13.695.827.426.160
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| Concept/Terms |
Cyclic GMP- Cyclic GMP
- GMP, Cyclic
- Guanosine Cyclic Monophosphate
- Cyclic Monophosphate, Guanosine
- Monophosphate, Guanosine Cyclic
- Guanosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Guanosine Cyclic
- Cyclic 3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3,5 Monophosphate
- Guanosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Guanosine
- Guanosine Cyclic 3',5' Monophosphate
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Below are MeSH descriptors whose meaning is more general than "Cyclic GMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP".
This graph shows the total number of publications written about "Cyclic GMP" by people in this website by year, and whether "Cyclic GMP" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 1 | 0 | 1 | | 1989 | 1 | 1 | 2 | | 1991 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 3 | 0 | 3 | | 2008 | 0 | 3 | 3 | | 2009 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclic GMP" by people in Profiles.
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Ma Y, Wang J, Yu Y, Schwartz RJ. PKG-1a mediates GATA4 transcriptional activity. Cell Signal. 2016 Jun; 28(6):585-94.
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Tanifum EA, Kots AY, Choi BK, Murad F, Gilbertson SR. Novel pyridopyrimidine derivatives as inhibitors of stable toxin a (STa) induced cGMP synthesis. Bioorg Med Chem Lett. 2009 Jun 01; 19(11):3067-71.
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Banday AA, Lokhandwala MF. Loss of biphasic effect on Na/K-ATPase activity by angiotensin II involves defective angiotensin type 1 receptor-nitric oxide signaling. Hypertension. 2008 Dec; 52(6):1099-105.
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Kots AY, Choi BK, Estrella-Jimenez ME, Warren CA, Gilbertson SR, Guerrant RL, Murad F. Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8440-5.
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Fitzgerald JB, Malykhina AP, Al-Ubaidi MR, Ding XQ. Functional expression of cone cyclic nucleotide-gated channel in cone photoreceptor-derived 661W cells. Adv Exp Med Biol. 2008; 613:327-34.
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Chen SK, Ko GY, Dryer SE. Somatostatin peptides produce multiple effects on gating properties of native cone photoreceptor cGMP-gated channels that depend on circadian phase and previous illumination. J Neurosci. 2007 Nov 07; 27(45):12168-75.
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Scott SP, Shea PW, Dryer SE. Mapping ligand interactions with the hyperpolarization activated cyclic nucleotide modulated (HCN) ion channel binding domain using a soluble construct. Biochemistry. 2007 Aug 21; 46(33):9417-31.
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Chae KS, Ko GY, Dryer SE. Tyrosine phosphorylation of cGMP-gated ion channels is under circadian control in chick retina photoreceptors. Invest Ophthalmol Vis Sci. 2007 Feb; 48(2):901-6.
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Choi M, Moschetta A, Bookout AL, Peng L, Umetani M, Holmstrom SR, Suino-Powell K, Xu HE, Richardson JA, Gerard RD, Mangelsdorf DJ, Kliewer SA. Identification of a hormonal basis for gallbladder filling. Nat Med. 2006 Nov; 12(11):1253-5.
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Ko GY, Ko M, Dryer SE. Circadian and cAMP-dependent modulation of retinal cone cGMP-gated channels does not require protein synthesis or calcium influx through L-type channels. Brain Res. 2004 Sep 24; 1021(2):277-80.
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