 Cyclic AMP
"Cyclic AMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH.
| Descriptor ID |
D000242
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| MeSH Number(s) |
D03.438.759.646.138.395 D13.695.462.200 D13.695.667.138.395 D13.695.827.068.395
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| Concept/Terms |
Cyclic AMP- Cyclic AMP
- AMP, Cyclic
- Adenosine Cyclic 3',5'-Monophosphate
- 3',5'-Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3',5' Monophosphate
- Cyclic 3',5'-Monophosphate, Adenosine
- Adenosine Cyclic-3',5'-Monophosphate
- Cyclic-3',5'-Monophosphate, Adenosine
- Adenosine Cyclic Monophosphate
- Cyclic Monophosphate, Adenosine
- Monophosphate, Adenosine Cyclic
- Adenosine Cyclic 3,5 Monophosphate
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Below are MeSH descriptors whose meaning is more general than "Cyclic AMP".
Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP".
This graph shows the total number of publications written about "Cyclic AMP" by people in this website by year, and whether "Cyclic AMP" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 1 | 0 | 1 | | 1985 | 1 | 0 | 1 | | 1986 | 1 | 2 | 3 | | 1987 | 2 | 1 | 3 | | 1988 | 3 | 0 | 3 | | 1989 | 5 | 0 | 5 | | 1990 | 4 | 1 | 5 | | 1991 | 1 | 3 | 4 | | 1992 | 2 | 1 | 3 | | 1993 | 5 | 0 | 5 | | 1994 | 4 | 2 | 6 | | 1995 | 3 | 3 | 6 | | 1996 | 1 | 4 | 5 | | 1997 | 2 | 1 | 3 | | 1998 | 4 | 5 | 9 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 3 | 4 | | 2001 | 1 | 3 | 4 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 6 | 6 | | 2004 | 3 | 1 | 4 | | 2005 | 0 | 2 | 2 | | 2006 | 1 | 3 | 4 | | 2007 | 1 | 2 | 3 | | 2008 | 0 | 2 | 2 | | 2010 | 1 | 1 | 2 | | 2011 | 0 | 4 | 4 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 4 | 4 | | 2014 | 1 | 2 | 3 | | 2015 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cyclic AMP" by people in Profiles.
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Al-Sawalha N, Pokkunuri I, Omoluabi O, Kim H, Thanawala VJ, Hernandez A, Bond RA, Knoll BJ. Epinephrine Activation of the ß2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells. PLoS One. 2015; 10(7):e0132559.
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Bigley AB, Rezvani K, Pistillo M, Reed J, Agha N, Kunz H, O'Connor DP, Sekine T, Bollard CM, Simpson RJ. Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells. Part II: impact of latent cytomegalovirus infection and catecholamine sensitivity. Brain Behav Immun. 2015 Oct; 49:59-65.
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Gherbi K, Briddon SJ, Hill SJ. Detection of the secondary, low-affinity ß1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP. Br J Pharmacol. 2014 Dec; 171(23):5431-45.
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Eby JC, Gray MC, Hewlett EL. Cyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin. Infect Immun. 2014 Dec; 82(12):5256-69.
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Stoddart LA, Kellam B, Briddon SJ, Hill SJ. Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization. Br J Pharmacol. 2014 Aug; 171(16):3827-44.
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Becker JR, Chatterjee S, Robinson TY, Bennett JS, Panáková D, Galindo CL, Zhong L, Shin JT, Coy SM, Kelly AE, Roden DM, Lim CC, MacRae CA. Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development. Development. 2014 Jan; 141(2):335-45.
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Baker JG, Proudman RG, Hill SJ. Impact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human ß1-adrenoceptor. PLoS One. 2013; 8(11):e77582.
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Guillory AN, Yin X, Wijaya CS, Diaz Diaz AC, Rababa'h A, Singh S, Atrooz F, Sadayappan S, McConnell BK. Enhanced cardiac function in Gravin mutant mice involves alterations in the ß-adrenergic receptor signaling cascade. PLoS One. 2013; 8(9):e74784.
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Mistry SN, Baker JG, Fischer PM, Hill SJ, Gardiner SM, Kellam B. Synthesis and in vitro and in vivo characterization of highly ß1-selective ß-adrenoceptor partial agonists. J Med Chem. 2013 May 23; 56(10):3852-65.
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Schein CH, Chen D, Ma L, Kanalas JJ, Gao J, Jimenez ME, Sower LE, Walter MA, Gilbertson SR, Peterson JW. Pharmacophore selection and redesign of non-nucleotide inhibitors of anthrax edema factor. Toxins (Basel). 2012 Nov 08; 4(11):1288-300.
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