 Heat-Shock Proteins
"Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and other environmental stresses. They increase thermal tolerance and perform functions essential to cell survival under these conditions.
| Descriptor ID |
D006360
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| MeSH Number(s) |
D12.776.580.216
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| Concept/Terms |
Heat-Shock Proteins- Heat-Shock Proteins
- Heat Shock Proteins
- Stress Proteins
- Heat-Shock Protein
- Heat Shock Protein
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Below are MeSH descriptors whose meaning is more general than "Heat-Shock Proteins".
Below are MeSH descriptors whose meaning is more specific than "Heat-Shock Proteins".
This graph shows the total number of publications written about "Heat-Shock Proteins" by people in this website by year, and whether "Heat-Shock Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1989 | 1 | 1 | 2 | | 1994 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1999 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 5 | 0 | 5 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Heat-Shock Proteins" by people in Profiles.
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Rosenzweig R, Moradi S, Zarrine-Afsar A, Glover JR, Kay LE. Unraveling the mechanism of protein disaggregation through a ClpB-DnaK interaction. Science. 2013 Mar 01; 339(6123):1080-3.
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West JD, Wang Y, Morano KA. Small molecule activators of the heat shock response: chemical properties, molecular targets, and therapeutic promise. Chem Res Toxicol. 2012 Oct 15; 25(10):2036-53.
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Wang Y, Gibney PA, West JD, Morano KA. The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds. Mol Biol Cell. 2012 Sep; 23(17):3290-8.
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Helsen CW, Glover JR. A new perspective on Hsp104-mediated propagation and curing of the yeast prion [PSI (+) ]. Prion. 2012 Jul 01; 6(3):234-9.
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Helsen CW, Glover JR. Insight into molecular basis of curing of [PSI+] prion by overexpression of 104-kDa heat shock protein (Hsp104). J Biol Chem. 2012 Jan 02; 287(1):542-56.
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Glover JR, Lum R. Remodeling of protein aggregates by Hsp104. Protein Pept Lett. 2009; 16(6):587-97.
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Mackay RG, Helsen CW, Tkach JM, Glover JR. The C-terminal extension of Saccharomyces cerevisiae Hsp104 plays a role in oligomer assembly. Biochemistry. 2008 Feb 19; 47(7):1918-27.
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Trott A, West JD, Klaic L, Westerheide SD, Silverman RB, Morimoto RI, Morano KA. Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule. Mol Biol Cell. 2008 Mar; 19(3):1104-12.
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Tkach JM, Glover JR. Nucleocytoplasmic trafficking of the molecular chaperone Hsp104 in unstressed and heat-shocked cells. Traffic. 2008 Jan; 9(1):39-56.
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Hindupur A, Liu D, Zhao Y, Bellamy HD, White MA, Fox RO. The crystal structure of the E. coli stress protein YciF. Protein Sci. 2006 Nov; 15(11):2605-11.
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