 Bone Morphogenetic Protein Receptors, Type II
"Bone Morphogenetic Protein Receptors, Type II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of bone morphogenetic protein receptors with low affinity for BONE MORPHOGENETIC PROTEINS. They are constitutively active PROTEIN-SERINE-THREONINE KINASES that can interact with and phosphorylate TYPE I BONE MORPHOGENETIC PROTEIN RECEPTORS.
| Descriptor ID |
D052006
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| MeSH Number(s) |
D08.811.913.696.620.682.700.109.750 D12.776.543.750.750.400.049.750
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| Concept/Terms |
Bone Morphogenetic Protein Receptors, Type II- Bone Morphogenetic Protein Receptors, Type II
- BMP Type II Receptors
- Receptor, Type II BMP
- BMPR2 Receptor
- Receptor, BMPR2
- Bone Morphogenetic Protein Receptor II
- Bone Morphogenetic Protein Receptor Type II
- BMP Type II Receptor
- BMPR-II Receptor
- BMPR II Receptor
- Receptor, BMPR-II
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Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein Receptors, Type II".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein Receptors, Type II".
This graph shows the total number of publications written about "Bone Morphogenetic Protein Receptors, Type II" by people in this website by year, and whether "Bone Morphogenetic Protein Receptors, Type II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2004 | 0 | 1 | 1 | | 2005 | 2 | 0 | 2 | | 2007 | 2 | 0 | 2 | | 2008 | 1 | 0 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 3 | 1 | 4 | | 2012 | 4 | 0 | 4 | | 2013 | 2 | 0 | 2 | | 2014 | 3 | 1 | 4 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Bone Morphogenetic Protein Receptors, Type II" by people in Profiles.
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Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR. Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle. Am J Respir Crit Care Med. 2016 Sep 15; 194(6):719-28.
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West JD, Carrier EJ, Bloodworth NC, Schroer AK, Chen P, Ryzhova LM, Gladson S, Shay S, Hutcheson JD, Merryman WD. Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension. PLoS One. 2016; 11(2):e0148657.
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Chen X, Talati M, Fessel JP, Hemnes AR, Gladson S, French J, Shay S, Trammell A, Phillips JA, Hamid R, Cogan JD, Dawson EP, Womble KE, Hedges LK, Martinez EG, Wheeler LA, Loyd JE, Majka SJ, West J, Austin ED. Estrogen Metabolite 16a-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II-Associated Pulmonary Arterial Hypertension Through MicroRNA-29-Mediated Modulation of Cellular Metabolism. Circulation. 2016 Jan 05; 133(1):82-97.
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West J, Austin E, Fessel JP, Loyd J, Hamid R. Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension. Drug Discov Today. 2014 Aug; 19(8):1241-5.
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Talati M, West J, Zaynagetdinov R, Hong CC, Han W, Blackwell T, Robinson L, Blackwell TS, Lane K. BMP pathway regulation of and by macrophages. PLoS One. 2014; 9(4):e94119.
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Gao X, Cao Y, Staloch DA, Gonzales MA, Aronson JF, Chao C, Hellmich MR, Ko TC. Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS One. 2014; 9(2):e89114.
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Hemnes AR, Brittain EL, Trammell AW, Fessel JP, Austin ED, Penner N, Maynard KB, Gleaves L, Talati M, Absi T, Disalvo T, West J. Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension. Am J Respir Crit Care Med. 2014 Feb 01; 189(3):325-34.
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Fessel JP, Flynn CR, Robinson LJ, Penner NL, Gladson S, Kang CJ, Wasserman DH, Hemnes AR, West JD. Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension. Am J Respir Cell Mol Biol. 2013 Nov; 49(5):778-87.
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Park SH, Chen WC, Hoffman C, Marsh LM, West J, Grunig G. Modification of hemodynamic and immune responses to exposure with a weak antigen by the expression of a hypomorphic BMPR2 gene. PLoS One. 2013; 8(1):e55180.
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West J, Niswender KD, Johnson JA, Pugh ME, Gleaves L, Fessel JP, Hemnes AR. A potential role for insulin resistance in experimental pulmonary hypertension. Eur Respir J. 2013 Apr; 41(4):861-71.
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