 Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
"Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4.
| Descriptor ID |
D008240
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| MeSH Number(s) |
D08.811.682.690.708.660
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| Concept/Terms |
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase- Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase
- 2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine
- 5-Dioxygenase Procollagen-Lysine, 2-Oxoglutarate
- Procollagen Lysine, 2 Oxoglutarate 5 Dioxygenase
- Lysine 2-Oxoglutarate Dioxygenase
- 2-Oxoglutarate Dioxygenase, Lysine
- Dioxygenase, Lysine 2-Oxoglutarate
- Lysine 2 Oxoglutarate Dioxygenase
- Lysyl Hydroxylase
- Hydroxylase, Lysyl
- Protocollagen Lysyl Hydroxylase
- Hydroxylase, Protocollagen Lysyl
- Collagen Lysyl Hydroxylase
- Hydroxylase, Collagen Lysyl
- Lysine Hydroxylase
- Hydroxylase, Lysine
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Below are MeSH descriptors whose meaning is more general than "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase".
Below are MeSH descriptors whose meaning is more specific than "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase".
This graph shows the total number of publications written about "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" by people in this website by year, and whether "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase" by people in Profiles.
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Chen Y, Guo H, Terajima M, Banerjee P, Liu X, Yu J, Momin AA, Katayama H, Hanash SM, Burns AR, Fields GB, Yamauchi M, Kurie JM. Lysyl Hydroxylase 2 Is Secreted by Tumor Cells and Can Modify Collagen in the Extracellular Space. J Biol Chem. 2016 Dec 09; 291(50):25799-25808.
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Chen Y, Terajima M, Yang Y, Sun L, Ahn YH, Pankova D, Puperi DS, Watanabe T, Kim MP, Blackmon SH, Rodriguez J, Liu H, Behrens C, Wistuba II, Minelli R, Scott KL, Sanchez-Adams J, Guilak F, Pati D, Thilaganathan N, Burns AR, Creighton CJ, Martinez ED, Zal T, Grande-Allen KJ, Yamauchi M, Kurie JM. Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. J Clin Invest. 2015 Mar 02; 125(3):1147-62.
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