 Nitric Oxide
"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
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| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
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| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
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Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1997 | 1 | 1 | 2 | | 1999 | 3 | 2 | 5 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 1 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 2 | 3 | | 2008 | 0 | 2 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 2 | 1 | 3 | | 2011 | 3 | 1 | 4 | | 2014 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Salim T, Sershen CL, May EE. Investigating the Role of TNF-a and IFN-? Activation on the Dynamics of iNOS Gene Expression in LPS Stimulated Macrophages. PLoS One. 2016; 11(6):e0153289.
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Muroya T, Kannan L, Ghiran IC, Shevkoplyas SS, Paz Z, Tsokos M, Dalle Lucca JJ, Shapiro NI, Tsokos GC. C4d deposits on the surface of RBCs in trauma patients and interferes with their function. Crit Care Med. 2014 May; 42(5):e364-72.
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Zhang XY, Zhou DF, Shen YC, Zhang PY, Zhang WF, Liang J, Chen DC, Xiu MH, Kosten TA, Kosten TR. Effects of risperidone and haloperidol on superoxide dismutase and nitric oxide in schizophrenia. Neuropharmacology. 2012 Apr; 62(5-6):1928-34.
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Javkhedkar AA, Lokhandwala MF, Banday AA. Defective nitric oxide production impairs angiotensin II-induced Na-K-ATPase regulation in spontaneously hypertensive rats. Am J Physiol Renal Physiol. 2012 Jan 01; 302(1):F47-51.
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Bhatt SR, Lokhandwala MF, Banday AA. Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats. Eur J Pharmacol. 2011 Sep 30; 667(1-3):258-64.
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Ghiran IC, Zeidel ML, Shevkoplyas SS, Burns JM, Tsokos GC, Kyttaris VC. Systemic lupus erythematosus serum deposits C4d on red blood cells, decreases red blood cell membrane deformability, and promotes nitric oxide production. Arthritis Rheum. 2011 Feb; 63(2):503-12.
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Tinberg CE, Tonzetich ZJ, Wang H, Do LH, Yoda Y, Cramer SP, Lippard SJ. Characterization of iron dinitrosyl species formed in the reaction of nitric oxide with a biological Rieske center. J Am Chem Soc. 2010 Dec 29; 132(51):18168-76.
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Min W, Xu LK, Zhou HJ, Huang Q, Zhang H, He Y, Zhe X, Luo Y. Thioredoxin and redox signaling in vasculature-studies using Trx2 endothelium-specific transgenic mice. Methods Enzymol. 2010; 474:315-24.
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Soldatova AV, Ibrahim M, Olson JS, Czernuszewicz RS, Spiro TG. New light on NO bonding in Fe(III) heme proteins from resonance Raman spectroscopy and DFT modeling. J Am Chem Soc. 2010 Apr 07; 132(13):4614-25.
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Banday AA, Lokhandwala MF. Inhibition of natriuretic factors increases blood pressure in rats. Am J Physiol Renal Physiol. 2009 Aug; 297(2):F397-402.
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