 Phencyclidine
"Phencyclidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.
| Descriptor ID |
D010622
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| MeSH Number(s) |
D03.383.621.699
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| Concept/Terms |
Phencyclidine- Phencyclidine
- 1-(1-Phenylcyclohexyl)piperidine
- Angel Dust
- Dust, Angel
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Below are MeSH descriptors whose meaning is more general than "Phencyclidine".
Below are MeSH descriptors whose meaning is more specific than "Phencyclidine".
This graph shows the total number of publications written about "Phencyclidine" by people in this website by year, and whether "Phencyclidine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1980 | 1 | 0 | 1 | | 1981 | 0 | 2 | 2 | | 1982 | 0 | 1 | 1 | | 1984 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phencyclidine" by people in Profiles.
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Carroll ME, Stotz DC, Kliner DJ, Meisch RA. Self-administration of orally-delivered methohexital in rhesus monkeys with phencyclidine or pentobarbital histories: effects of food deprivation and satiation. Pharmacol Biochem Behav. 1984 Jan; 20(1):145-51.
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Volle RL, Alkadhi KA, Branisteanu DD, Reynolds LS, Epstein PM, Smilowitz H, Lambert JJ, Henderson EG. Ketamine and ditran block end-plate ion conductance and [3H]phencyclidine binding to electric organ membrane. J Pharmacol Exp Ther. 1982 Jun; 221(3):570-6.
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Meisch RA, Carroll ME. Establishment of orally delivered drugs as reinforcers for rhesus monkeys: some relations to human drug dependence. NIDA Res Monogr. 1981 Jul; 37:197-209.
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Carroll ME, France CP, Meisch RA. Intravenous self-administration of etonitazene, cocaine and phencyclidine in rats during food deprivation and satiation. J Pharmacol Exp Ther. 1981 May; 217(2):241-7.
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Carroll ME, Meisch RA. Oral phencyclidine (PCP) self-administration in rhesus monkeys: effects of feeding conditions. J Pharmacol Exp Ther. 1980 Aug; 214(2):339-46.
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