Phenobarbital
"Phenobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Descriptor ID |
D010634
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MeSH Number(s) |
D03.383.742.698.253.650
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Concept/Terms |
Phenobarbital- Phenobarbital
- Phenobarbitone
- Phenylethylbarbituric Acid
- Acid, Phenylethylbarbituric
- Phenemal
- Phenylbarbital
Phenobarbital Sodium- Phenobarbital Sodium
- Sodium, Phenobarbital
- Phenobarbital, Monosodium Salt
- Monosodium Salt Phenobarbital
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Below are MeSH descriptors whose meaning is more general than "Phenobarbital".
Below are MeSH descriptors whose meaning is more specific than "Phenobarbital".
This graph shows the total number of publications written about "Phenobarbital" by people in this website by year, and whether "Phenobarbital" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1980 | 0 | 1 | 1 |
1998 | 1 | 1 | 2 |
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Below are the most recent publications written about "Phenobarbital" by people in Profiles.
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Meisch RA, Spiga R. Matching under nonindependent variable-ratio schedules of drug reinforcement. J Exp Anal Behav. 1998 Jul; 70(1):23-34.
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Otoom S, Tian LM, Alkadhi KA. Veratridine-treated brain slices: a cellular model for epileptiform activity. Brain Res. 1998 Apr 06; 789(1):150-6.
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Nautsch JP, Rolf LH, Brune GG. A rapid gas liquid chromatography method for simultaneous determination of various anticonvulsants. J Neurol. 1980; 223(3):219-23.