 Rho Factor
"Rho Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein which effects termination of RNA synthesis during the genetic transcription process by dissociating the ternary transcription complex RNA;-RNA POLYMERASE DNA at the termination of a gene.
| Descriptor ID |
D012234
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| MeSH Number(s) |
D12.776.930.785
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Rho Factor".
Below are MeSH descriptors whose meaning is more specific than "Rho Factor".
This graph shows the total number of publications written about "Rho Factor" by people in this website by year, and whether "Rho Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 2000 | 2 | 0 | 2 | | 2001 | 0 | 1 | 1 | | 2002 | 2 | 0 | 2 | | 2003 | 3 | 1 | 4 | | 2005 | 2 | 1 | 3 |
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Below are the most recent publications written about "Rho Factor" by people in Profiles.
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Kohn H, Widger W. The molecular basis for the mode of action of bicyclomycin. Curr Drug Targets Infect Disord. 2005 Sep; 5(3):273-95.
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Brogan AP, Widger WR, Bensadek D, Riba-Garcia I, Gaskell SJ, Kohn H. Development of a technique to determine bicyclomycin-rho binding and stoichiometry by isothermal titration calorimetry and mass spectrometry. J Am Chem Soc. 2005 Mar 02; 127(8):2741-51.
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Brogan AP, Verghese J, Widger WR, Kohn H. Bismuth-dithiol inhibition of the Escherichia coli rho transcription termination factor. J Inorg Biochem. 2005 Mar; 99(3):841-51.
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Weber TP, Widger WR, Kohn H. Metal-1,4-dithio-2,3-dihydroxybutane chelates: novel inhibitors of the Rho transcription termination factor. Biochemistry. 2003 Aug 05; 42(30):9121-6.
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Brogan AP, Widger WR, Kohn H. Bicyclomycin fluorescent probes: synthesis and biochemical, biophysical, and biological properties. J Org Chem. 2003 Jul 11; 68(14):5575-87.
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Weber TP, Widger WR, Kohn H. Metal dependency for transcription factor rho activation. Biochemistry. 2003 Feb 18; 42(6):1652-9.
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Xu Y, Johnson J, Kohn H, Widger WR. ATP binding to Rho transcription termination factor. Mutant F355W ATP-induced fluorescence quenching reveals dynamic ATP binding. J Biol Chem. 2003 Apr 18; 278(16):13719-27.
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Weber TP, Widger WR, Kohn H. The Mg2+ requirements for rho transcription termination factor: catalysis and bicyclomycin inhibition. Biochemistry. 2002 Oct 15; 41(41):12377-83.
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Xu Y, Kohn H, Widger WR. Mutations in the rho transcription termination factor that affect RNA tracking. J Biol Chem. 2002 Aug 16; 277(33):30023-30.
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Vincent F, Srinivasan J, Santillán A, Widger WR, Kohn H. C(5)-C(5a)-modified bicyclomycins: synthesis, structure, and biochemical and biological properties. J Org Chem. 2001 Apr 06; 66(7):2251-64.
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