 Serine
"Serine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
| Descriptor ID |
D012694
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| MeSH Number(s) |
D12.125.154.800
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Serine".
Below are MeSH descriptors whose meaning is more specific than "Serine".
This graph shows the total number of publications written about "Serine" by people in this website by year, and whether "Serine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 3 | 3 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 2 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 6 | 6 | | 2007 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serine" by people in Profiles.
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Awwad HO, Millman EE, Alpizar-Foster E, Moore RH, Knoll BJ. Mutating the dileucine motif of the human beta(2)-adrenoceptor reduces the high initial rate of receptor phosphorylation by GRK without affecting postendocytic sorting. Eur J Pharmacol. 2010 Jun 10; 635(1-3):9-15.
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Banday AA, Lokhandwala MF. Inhibition of natriuretic factors increases blood pressure in rats. Am J Physiol Renal Physiol. 2009 Aug; 297(2):F397-402.
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Seol GH, Ziburkus J, Huang S, Song L, Kim IT, Takamiya K, Huganir RL, Lee HK, Kirkwood A. Neuromodulators control the polarity of spike-timing-dependent synaptic plasticity. Neuron. 2007 Sep 20; 55(6):919-29.
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Fardoun RZ, Asghar M, Lokhandwala M. Role of oxidative stress in defective renal dopamine D1 receptor-G protein coupling and function in old Fischer 344 rats. Am J Physiol Renal Physiol. 2006 Nov; 291(5):F945-51.
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Konde V, Eichberg J. Myelin protein zero: mutations in the cytoplasmic domain interfere with its cellular trafficking. J Neurosci Res. 2006 May 01; 83(6):957-64.
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Zimmerman TL, Thevananther S, Ghose R, Burns AR, Karpen SJ. Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260. J Biol Chem. 2006 Jun 02; 281(22):15434-40.
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Iyer D, Chang D, Marx J, Wei L, Olson EN, Parmacek MS, Balasubramanyam A, Schwartz RJ. Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4516-21.
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Iyer V, Tran TM, Foster E, Dai W, Clark RB, Knoll BJ. Differential phosphorylation and dephosphorylation of beta2-adrenoceptor sites Ser262 and Ser355,356. Br J Pharmacol. 2006 Feb; 147(3):249-59.
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Vaughan DJ, Millman EE, Godines V, Friedman J, Tran TM, Dai W, Knoll BJ, Clark RB, Moore RH. Role of the G protein-coupled receptor kinase site serine cluster in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation. J Biol Chem. 2006 Mar 17; 281(11):7684-92.
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Asghar M, Banday AA, Fardoun RZ, Lokhandwala MF. Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2. Free Radic Biol Med. 2006 Jan 01; 40(1):13-20.
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