Sertoli Cells
"Sertoli Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Supporting cells projecting inward from the basement membrane of SEMINIFEROUS TUBULES. They surround and nourish the developing male germ cells and secrete ANDROGEN-BINDING PROTEIN and hormones such as ANTI-MULLERIAN HORMONE. The tight junctions of Sertoli cells with the SPERMATOGONIA and SPERMATOCYTES provide a BLOOD-TESTIS BARRIER.
Descriptor ID |
D012708
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MeSH Number(s) |
A05.360.444.849.789 A11.382.952 A11.436.837
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sertoli Cells".
Below are MeSH descriptors whose meaning is more specific than "Sertoli Cells".
This graph shows the total number of publications written about "Sertoli Cells" by people in this website by year, and whether "Sertoli Cells" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 1 | 0 | 1 | 2003 | 1 | 0 | 1 | 2005 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sertoli Cells" by people in Profiles.
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MacLean JA, Hu Z, Welborn JP, Song HW, Rao MK, Wayne CM, Wilkinson MF. The RHOX homeodomain proteins regulate the expression of insulin and other metabolic regulators in the testis. J Biol Chem. 2013 Nov 29; 288(48):34809-25.
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Maclean JA, Chen MA, Wayne CM, Bruce SR, Rao M, Meistrich ML, Macleod C, Wilkinson MF. Rhox: a new homeobox gene cluster. Cell. 2005 Feb 11; 120(3):369-82.
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Rao MK, Wayne CM, Meistrich ML, Wilkinson MF. Pem homeobox gene promoter sequences that direct transcription in a Sertoli cell-specific, stage-specific, and androgen-dependent manner in the testis in vivo. Mol Endocrinol. 2003 Feb; 17(2):223-33.
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Wayne CM, Sutton K, Wilkinson MF. Expression of the pem homeobox gene in Sertoli cells increases the frequency of adjacent germ cells with deoxyribonucleic acid strand breaks. Endocrinology. 2002 Dec; 143(12):4875-85.
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