Cytochalasin D
"Cytochalasin D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
Descriptor ID |
D015638
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MeSH Number(s) |
D03.438.473.231.450 D23.946.587.370.450
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cytochalasin D".
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This graph shows the total number of publications written about "Cytochalasin D" by people in this website by year, and whether "Cytochalasin D" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochalasin D" by people in Profiles.
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Anderson M, Kim EY, Hagmann H, Benzing T, Dryer SE. Opposing effects of podocin on the gating of podocyte TRPC6 channels evoked by membrane stretch or diacylglycerol. Am J Physiol Cell Physiol. 2013 Aug 01; 305(3):C276-89.
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Donato GM, Goldsmith CS, Paddock CD, Eby JC, Gray MC, Hewlett EL. Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles. FEBS Lett. 2012 Feb 17; 586(4):459-65.
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Millman EE, Zhang H, Zhang H, Godines V, Bean AJ, Knoll BJ, Moore RH. Rapid recycling of beta-adrenergic receptors is dependent on the actin cytoskeleton and myosin Vb. Traffic. 2008 Nov; 9(11):1958-71.
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Wei L, Wang L, Carson JA, Agan JE, Imanaka-Yoshida K, Schwartz RJ. beta1 integrin and organized actin filaments facilitate cardiomyocyte-specific RhoA-dependent activation of the skeletal alpha-actin promoter. FASEB J. 2001 Mar; 15(3):785-96.
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