Cadherins
"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
Descriptor ID |
D015820
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MeSH Number(s) |
D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
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Concept/Terms |
P-Cadherins- P-Cadherins
- P Cadherins
- P-Cadherin
- P Cadherin
- Placental Cadherins
- Cadherins, Placental
- Cadherin-3
- Cadherin 3
E-Cadherins- E-Cadherins
- E Cadherins
- Uvomorulin
- Epithelial-Cadherins
- Epithelial Cadherins
- Cadherin-1
- Cadherin 1
- E-Cadherin
- E Cadherin
N-Cadherins- N-Cadherins
- N Cadherins
- N-Cadherin
- N Cadherin
- Neural Cadherins
- Cadherins, Neural
- Cadherin-2
- Cadherin 2
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Below are MeSH descriptors whose meaning is more general than "Cadherins".
Below are MeSH descriptors whose meaning is more specific than "Cadherins".
This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 | 2006 | 1 | 0 | 1 | 2009 | 1 | 1 | 2 | 2011 | 0 | 1 | 1 | 2012 | 0 | 2 | 2 | 2013 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 | 2016 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cadherins" by people in Profiles.
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Bijli KM, Fazal F, Slavin SA, Leonard A, Grose V, Alexander WB, Smrcka AV, Rahman A. Phospholipase C-e signaling mediates endothelial cell inflammation and barrier disruption in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 01; 311(2):L517-24.
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Li J, Miao L, Shieh D, Spiotto E, Li J, Zhou B, Paul A, Schwartz RJ, Firulli AB, Singer HA, Huang G, Wu M. Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification. Cell Rep. 2016 Apr 05; 15(1):158-70.
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Li G, Li CX, Xia M, Ritter JK, Gehr TW, Boini K, Li PL. Enhanced epithelial-to-mesenchymal transition associated with lysosome dysfunction in podocytes: role of p62/Sequestosome 1 as a signaling hub. Cell Physiol Biochem. 2015; 35(5):1773-86.
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Bernhard OK, Greening DW, Barnes TW, Ji H, Simpson RJ. Detection of cadherin-17 in human colon cancer LIM1215 cell secretome and tumour xenograft-derived interstitial fluid and plasma. Biochim Biophys Acta. 2013 Nov; 1834(11):2372-9.
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Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, Iseki S, Schwartz RJ, Okamoto H, Sasaki T, Matsui O, Asano M, Adams RH, Takakura N, Takuwa Y. Endothelial PI3K-C2a, a class II PI3K, has an essential role in angiogenesis and vascular barrier function. Nat Med. 2012 Oct; 18(10):1560-9.
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Munoz WA, Kloc M, Cho K, Lee M, Hofmann I, Sater A, Vleminckx K, McCrea PD. Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues. PLoS One. 2012; 7(4):e34342.
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Zhang C, Xia M, Boini KM, Li CX, Abais JM, Li XX, Laperle LA, Li PL. Epithelial-to-mesenchymal transition in podocytes mediated by activation of NADPH oxidase in hyperhomocysteinemia. Pflugers Arch. 2011 Sep; 462(3):455-67.
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Gu D, Sater AK, Ji H, Cho K, Clark M, Stratton SA, Barton MC, Lu Q, McCrea PD. Xenopus delta-catenin is essential in early embryogenesis and is functionally linked to cadherins and small GTPases. J Cell Sci. 2009 Nov 15; 122(Pt 22):4049-61.
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Hamaratoglu F, Gajewski K, Sansores-Garcia L, Morrison C, Tao C, Halder G. The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth. J Cell Sci. 2009 Jul 15; 122(Pt 14):2351-9.
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Catimel B, Layton M, Church N, Ross J, Condron M, Faux M, Simpson RJ, Burgess AW, Nice EC. In situ phosphorylation of immobilized receptors on biosensor surfaces: application to E-cadherin/beta-catenin interactions. Anal Biochem. 2006 Oct 15; 357(2):277-88.
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