Protein Structure, Tertiary
"Protein Structure, Tertiary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The level of protein structure in which combinations of secondary protein structures (alpha helices, beta sheets, loop regions, and motifs) pack together to form folded shapes called domains. Disulfide bridges between cysteines in two different parts of the polypeptide chain along with other interactions between the chains play a role in the formation and stabilization of tertiary structure. Small proteins usually consist of only one domain but larger proteins may contain a number of domains connected by segments of polypeptide chain which lack regular secondary structure.
Descriptor ID |
D017434
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MeSH Number(s) |
G02.111.570.820.709.610
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Concept/Terms |
Protein Structure, Tertiary- Protein Structure, Tertiary
- Peptide Domain
- Domain, Peptide
- Domains, Peptide
- Peptide Domains
- Protein Domains
- Domain, Protein
- Domains, Protein
- Protein Domain
- Tertiary Protein Structure
- Protein Structures, Tertiary
- Tertiary Protein Structures
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Below are MeSH descriptors whose meaning is more general than "Protein Structure, Tertiary".
Below are MeSH descriptors whose meaning is more specific than "Protein Structure, Tertiary".
This graph shows the total number of publications written about "Protein Structure, Tertiary" by people in this website by year, and whether "Protein Structure, Tertiary" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 2 | 2 | 2000 | 0 | 3 | 3 | 2001 | 0 | 4 | 4 | 2002 | 1 | 5 | 6 | 2003 | 0 | 8 | 8 | 2004 | 0 | 9 | 9 | 2005 | 0 | 12 | 12 | 2006 | 0 | 5 | 5 | 2007 | 0 | 9 | 9 | 2008 | 1 | 7 | 8 | 2009 | 0 | 3 | 3 | 2010 | 0 | 7 | 7 | 2011 | 0 | 8 | 8 | 2012 | 0 | 10 | 10 | 2013 | 0 | 2 | 2 | 2014 | 0 | 3 | 3 | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Structure, Tertiary" by people in Profiles.
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Stuck MW, Conley SM, Naash MI. RDS Functional Domains and Dysfunction in Disease. Adv Exp Med Biol. 2016; 854:217-22.
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Cheng G, Zhong M, Kawaguchi R, Kassai M, Al-Ubaidi M, Deng J, Ter-Stepanian M, Sun H. Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF. Elife. 2014 Dec 23; 3:e05401.
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Lee S, Kang D, Ra EA, Lee TA, Ploegh HL, Park B. Negative self-regulation of TLR9 signaling by its N-terminal proteolytic cleavage product. J Immunol. 2014 Oct 01; 193(7):3726-35.
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Stoddart LA, Kellam B, Briddon SJ, Hill SJ. Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization. Br J Pharmacol. 2014 Aug; 171(16):3827-44.
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Rosenzweig R, Moradi S, Zarrine-Afsar A, Glover JR, Kay LE. Unraveling the mechanism of protein disaggregation through a ClpB-DnaK interaction. Science. 2013 Mar 01; 339(6123):1080-3.
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He L, Vandin F, Pandurangan G, Bailey-Kellogg C. Ballast: a ball-based algorithm for structural motifs. J Comput Biol. 2013 Feb; 20(2):137-51.
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Chakraborty D, Rodgers KK, Conley SM, Naash MI. Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS. FEBS J. 2013 Jan; 280(1):127-38.
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Wilkinson OJ, Latypov V, Tubbs JL, Millington CL, Morita R, Blackburn H, Marriott A, McGown G, Thorncroft M, Watson AJ, Connolly BA, Grasby JA, Masui R, Hunter CA, Tainer JA, Margison GP, Williams DM. Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-p interactions. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):18755-60.
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Mallipeddi PL, Joshi M, Briggs JM. Pharmacophore-based virtual screening to aid in the identification of unknown protein function. Chem Biol Drug Des. 2012 Dec; 80(6):828-42.
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Murray MJ, Ng MM, Fraval H, Tan J, Liu W, Smallhorn M, Brill JA, Field SJ, Saint R. Regulation of Drosophila mesoderm migration by phosphoinositides and the PH domain of the Rho GTP exchange factor Pebble. Dev Biol. 2012 Dec 01; 372(1):17-27.
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