Gelsolin
"Gelsolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 90-kDa protein produced by macrophages that severs ACTIN filaments and forms a cap on the newly exposed filament end. Gelsolin is activated by CALCIUM ions and participates in the assembly and disassembly of actin, thereby increasing the motility of some CELLS.
| Descriptor ID |
D018260
|
| MeSH Number(s) |
D05.750.078.730.350 D12.644.360.381.437 D12.776.157.125.412.437 D12.776.220.525.350 D12.776.476.387.437
|
| Concept/Terms |
Gelsolin- Gelsolin
- Serum Actin Inhibitory Protein
- Gelsolin Protein
|
Below are MeSH descriptors whose meaning is more general than "Gelsolin".
Below are MeSH descriptors whose meaning is more specific than "Gelsolin".
This graph shows the total number of publications written about "Gelsolin" by people in this website by year, and whether "Gelsolin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gelsolin" by people in Profiles.
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Gajewski KM, Wang J, Schulz RA. Calcineurin function is required for myofilament formation and troponin I isoform transition in Drosophila indirect flight muscle. Dev Biol. 2006 Jan 01; 289(1):17-29.
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Schneider MD, Schwartz RJ. Chips ahoy: gene expression in failing hearts surveyed by high-density microarrays. Circulation. 2000 Dec 19; 102(25):3026-7.
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Chen KS, Gunaratne PH, Hoheisel JD, Young IG, Miklos GL, Greenberg F, Shaffer LG, Campbell HD, Lupski JR. The human homologue of the Drosophila melanogaster flightless-I gene (flil) maps within the Smith-Magenis microdeletion critical region in 17p11.2. Am J Hum Genet. 1995 Jan; 56(1):175-82.