 Cyclin D1
"Cyclin D1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.
| Descriptor ID |
D019938
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| MeSH Number(s) |
D12.644.360.262.150.100 D12.776.167.218.150.100 D12.776.476.262.150.100 D12.776.624.664.700.100
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| Concept/Terms |
Cyclin D1- Cyclin D1
- c-bcl-1 Proteins
- c bcl 1 Proteins
- CCND1 Protein
- bcl-1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl-1
- bcl 1 Proto Oncogene Proteins
- Proto-Oncogene Products bcl-1
- Proto Oncogene Products bcl 1
- Proto-Oncogene Protein bcl-1
- Proto Oncogene Protein bcl 1
- bcl-1, Proto-Oncogene Protein
- Proto-Oncogene Proteins c-bcl-1
- Proto Oncogene Proteins c bcl 1
- c-bcl-1, Proto-Oncogene Proteins
- bcl-1 Proto-Oncogene Products
- Proto-Oncogene Products, bcl-1
- bcl 1 Proto Oncogene Products
- bcl1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl1
- bcl1 Proto Oncogene Proteins
- PRAD1 Protein
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Below are MeSH descriptors whose meaning is more general than "Cyclin D1".
Below are MeSH descriptors whose meaning is more specific than "Cyclin D1".
This graph shows the total number of publications written about "Cyclin D1" by people in this website by year, and whether "Cyclin D1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2009 | 1 | 1 | 2 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin D1" by people in Profiles.
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Dyari HR, Rawling T, Bourget K, Murray M. Synthetic ?-3 epoxyfatty acids as antiproliferative and pro-apoptotic agents in human breast cancer cells. J Med Chem. 2014 Sep 11; 57(17):7459-64.
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Cui PH, Petrovic N, Murray M. The ?-3 epoxide of eicosapentaenoic acid inhibits endothelial cell proliferation by p38 MAP kinase activation and cyclin D1/CDK4 down-regulation. Br J Pharmacol. 2011 Mar; 162(5):1143-55.
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Gray MC, Hewlett EL. Cell cycle arrest induced by the bacterial adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Cell Microbiol. 2011 Jan; 13(1):123-34.
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Byrne A, McLaren RP, Mason P, Chai L, Dufault MR, Huang Y, Liang B, Gans JD, Zhang M, Carter K, Gladysheva TB, Teicher BA, Biemann HP, Booker M, Goldberg MA, Klinger KW, Lillie J, Madden SL, Jiang Y. Knockdown of human deubiquitinase PSMD14 induces cell cycle arrest and senescence. Exp Cell Res. 2010 Jan 15; 316(2):258-71.
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Sukov WR, Ketterling RP, Lager DJ, Carlson AW, Sinnwell JP, Chow GK, Jenkins RB, Cheville JC. CCND1 rearrangements and cyclin D1 overexpression in renal oncocytomas: frequency, clinicopathologic features, and utility in differentiation from chromophobe renal cell carcinoma. Hum Pathol. 2009 Sep; 40(9):1296-303.
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Cheng G, Weihua Z, Warner M, Gustafsson JA. Estrogen receptors ER alpha and ER beta in proliferation in the rodent mammary gland. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3739-46.
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