 Two-Hybrid System Techniques
"Two-Hybrid System Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Screening techniques first developed in yeast to identify genes encoding interacting proteins. Variations are used to evaluate interplay between proteins and other molecules. Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions or ligand-based interactions. Reverse n-hybrid techniques refer to analysis for mutations or other small molecules that dissociate known interactions.
| Descriptor ID |
D020798
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| MeSH Number(s) |
E05.393.220.870 E05.601.690.650 E05.601.870
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| Concept/Terms |
Two-Hybrid System Techniques- Two-Hybrid System Techniques
- Technique, Two-Hybrid System
- Techniques, Two-Hybrid System
- Two Hybrid System Techniques
- Two-Hybrid System Technique
- Two-Hybrid Method
- Method, Two-Hybrid
- Methods, Two-Hybrid
- Two Hybrid Method
- Two-Hybrid Methods
- Two-Hybrid System Technics
- Technic, Two-Hybrid System
- Technics, Two-Hybrid System
- Two Hybrid System Technics
- Two-Hybrid System Technic
- Two-Hybrid Assay
- Assay, Two-Hybrid
- Assays, Two-Hybrid
- Two Hybrid Assay
- Two-Hybrid Assays
One-Hybrid System Techniques- One-Hybrid System Techniques
- One Hybrid System Techniques
- One-Hybrid System Technique
- Technique, One-Hybrid System
- Techniques, One-Hybrid System
- One-Hybrid System Technics
- One Hybrid System Technics
- One-Hybrid System Technic
- Technic, One-Hybrid System
- Technics, One-Hybrid System
Yeast Two-Hybrid System Techniques- Yeast Two-Hybrid System Techniques
- Yeast Two Hybrid System Techniques
- Yeast Two-Hybrid System
- System, Yeast Two-Hybrid
- Systems, Yeast Two-Hybrid
- Two-Hybrid System, Yeast
- Two-Hybrid Systems, Yeast
- Yeast Two Hybrid System
- Yeast Two-Hybrid Systems
- Yeast Two-Hybrid Assay
- Assay, Yeast Two-Hybrid
- Assays, Yeast Two-Hybrid
- Two-Hybrid Assay, Yeast
- Two-Hybrid Assays, Yeast
- Yeast Two Hybrid Assay
- Yeast Two-Hybrid Assays
Three-Hybrid System Techniques- Three-Hybrid System Techniques
- Technique, Three-Hybrid System
- Techniques, Three-Hybrid System
- Three Hybrid System Techniques
- Three-Hybrid System Technique
- Tri-Hybrid System Techniques
- Technique, Tri-Hybrid System
- Techniques, Tri-Hybrid System
- Tri Hybrid System Techniques
- Tri-Hybrid System Technique
- Three-Hybrid System Technics
- Technic, Three-Hybrid System
- Technics, Three-Hybrid System
- Three Hybrid System Technics
- Three-Hybrid System Technic
Yeast Three-Hybrid System Techniques- Yeast Three-Hybrid System Techniques
- Yeast Three Hybrid System Techniques
- Yeast Three-Hybrid System
- System, Yeast Three-Hybrid
- Systems, Yeast Three-Hybrid
- Three-Hybrid System, Yeast
- Three-Hybrid Systems, Yeast
- Yeast Three Hybrid System
- Yeast Three-Hybrid Systems
- Yeast Three-Hybrid Assay
- Assay, Yeast Three-Hybrid
- Assays, Yeast Three-Hybrid
- Three-Hybrid Assay, Yeast
- Three-Hybrid Assays, Yeast
- Yeast Three Hybrid Assay
- Yeast Three-Hybrid Assays
n-Hybrid System Techniques- n-Hybrid System Techniques
- System Technique, n-Hybrid
- System Techniques, n-Hybrid
- Technique, n-Hybrid System
- Techniques, n-Hybrid System
- n Hybrid System Techniques
- n-Hybrid System Technique
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Below are MeSH descriptors whose meaning is more general than "Two-Hybrid System Techniques".
Below are MeSH descriptors whose meaning is more specific than "Two-Hybrid System Techniques".
This graph shows the total number of publications written about "Two-Hybrid System Techniques" by people in this website by year, and whether "Two-Hybrid System Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Two-Hybrid System Techniques" by people in Profiles.
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Sartain CV, Cui J, Meisel RP, Wolfner MF. The poly(A) polymerase GLD2 is required for spermatogenesis in Drosophila melanogaster. Development. 2011 Apr; 138(8):1619-29.
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Jha S, Dryer SE. The beta1 subunit of Na+/K+-ATPase interacts with BKCa channels and affects their steady-state expression on the cell surface. FEBS Lett. 2009 Oct 06; 583(19):3109-14.
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Ridgway LD, Kim EY, Dryer SE. MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface. Am J Physiol Cell Physiol. 2009 Jul; 297(1):C55-65.
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Kim EY, Choi KJ, Dryer SE. Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface. Am J Physiol Renal Physiol. 2008 Jul; 295(1):F235-46.
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Kim EY, Ridgway LD, Dryer SE. Interactions with filamin A stimulate surface expression of large-conductance Ca2+-activated K+ channels in the absence of direct actin binding. Mol Pharmacol. 2007 Sep; 72(3):622-30.
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Yan Q, Sun W, Kujala P, Lotfi Y, Vida TA, Bean AJ. CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling. Mol Biol Cell. 2005 May; 16(5):2470-82.
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Otteson DC, Liu Y, Lai H, Wang C, Gray S, Jain MK, Zack DJ. Kruppel-like factor 15, a zinc-finger transcriptional regulator, represses the rhodopsin and interphotoreceptor retinoid-binding protein promoters. Invest Ophthalmol Vis Sci. 2004 Aug; 45(8):2522-30.
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Brown CO, Chi X, Garcia-Gras E, Shirai M, Feng XH, Schwartz RJ. The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J Biol Chem. 2004 Mar 12; 279(11):10659-69.
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