Potassium Channel Blockers
"Potassium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.
Descriptor ID |
D026902
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MeSH Number(s) |
D27.505.519.562.500 D27.505.954.411.645
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Potassium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Potassium Channel Blockers".
This graph shows the total number of publications written about "Potassium Channel Blockers" by people in this website by year, and whether "Potassium Channel Blockers" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2002 | 1 | 0 | 1 | 2003 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Potassium Channel Blockers" by people in Profiles.
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Chen Y, Li X, Boini KM, Pitzer AL, Gulbins E, Zhang Y, Li PL. Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis. Biochim Biophys Acta. 2015 Feb; 1853(2):396-408.
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Kim SJ, Zhang H, Khaliulin I, Choisy SC, Bond R, Lin H, El Haou S, Milnes JT, Hancox JC, Suleiman MS, James AF. Activation of glibenclamide-sensitive ATP-sensitive K+ channels during ß-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia. Circ Arrhythm Electrophysiol. 2012 Dec; 5(6):1184-92.
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Alkadhi KA. Rhythmic discharge induced by temperature variation and drugs in isolated sympathetic ganglia. Clin Exp Hypertens. 2008 Oct; 30(7):497-510.
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Bryan RM, You J, Phillips SC, Andresen JJ, Lloyd EE, Rogers PA, Dryer SE, Marrelli SP. Evidence for two-pore domain potassium channels in rat cerebral arteries. Am J Physiol Heart Circ Physiol. 2006 Aug; 291(2):H770-80.
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Vogalis F, Harvey JR. Altered excitability of intestinal neurons in primary culture caused by acute oxidative stress. J Neurophysiol. 2003 Jun; 89(6):3039-50.
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Liu B, Arulkumaran S, Hill SJ, Khan RN. Comparison of potassium currents in human decidua before and after the onset of labor. Biol Reprod. 2003 Jun; 68(6):2281-8.
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Vogalis F, Harvey JR, Furness JB. TEA- and apamin-resistant K(Ca) channels in guinea-pig myenteric neurons: slow AHP channels. J Physiol. 2002 Jan 15; 538(Pt 2):421-33.
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Cui M, Shen J, Briggs JM, Luo X, Tan X, Jiang H, Chen K, Ji R. Brownian dynamics simulations of interaction between scorpion toxin Lq2 and potassium ion channel. Biophys J. 2001 Apr; 80(4):1659-69.
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