Sodium Channel Blockers
"Sodium Channel Blockers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of drugs that act by inhibition of sodium influx through cell membranes. Blockade of sodium channels slows the rate and amplitude of initial rapid depolarization, reduces cell excitability, and reduces conduction velocity.
| Descriptor ID |
D026941
|
| MeSH Number(s) |
D27.505.519.562.750 D27.505.954.411.720
|
| Concept/Terms |
Sodium Channel Blockers- Sodium Channel Blockers
- Sodium Channel Inhibitors
- Channel Inhibitors, Sodium
- Inhibitors, Sodium Channel
- Channel Blockers, Sodium
|
Below are MeSH descriptors whose meaning is more general than "Sodium Channel Blockers".
Below are MeSH descriptors whose meaning is more specific than "Sodium Channel Blockers".
This graph shows the total number of publications written about "Sodium Channel Blockers" by people in this website by year, and whether "Sodium Channel Blockers" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sodium Channel Blockers" by people in Profiles.
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Luo X, Frishman LJ. Retinal pathway origins of the pattern electroretinogram (PERG). Invest Ophthalmol Vis Sci. 2011 Nov 01; 52(12):8571-84.
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Djakovic SN, Schwarz LA, Barylko B, DeMartino GN, Patrick GN. Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II. J Biol Chem. 2009 Sep 25; 284(39):26655-65.
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Miura G, Wang MH, Ivers KM, Frishman LJ. Retinal pathway origins of the pattern ERG of the mouse. Exp Eye Res. 2009 Jun 15; 89(1):49-62.
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Mojumder DK, Sherry DM, Frishman LJ. Contribution of voltage-gated sodium channels to the b-wave of the mammalian flash electroretinogram. J Physiol. 2008 May 15; 586(10):2551-80.
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Yeiser AJ, Cox JR, Wright SN. Voltage-dependent inhibition of rat skeletal muscle sodium channels by aminoglycoside antibiotics. Pflugers Arch. 2004 May; 448(2):204-13.