Epithelial Sodium Channels
"Epithelial Sodium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.
Descriptor ID |
D053503
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MeSH Number(s) |
D12.776.157.530.400.875.200 D12.776.543.550.425.875.200 D12.776.543.585.400.875.200
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Concept/Terms |
Epithelial Sodium Channels- Epithelial Sodium Channels
- Sodium Channels, Epithelial
- Epithelial Sodium Ion Channels
- Epithelial Sodium Channel
- Sodium Channel, Epithelial
- ENaC (Epithelial Na+ Channel)
- Epithelial Amiloride-Sensitive Sodium Channel
- Epithelial Amiloride Sensitive Sodium Channel
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Below are MeSH descriptors whose meaning is more general than "Epithelial Sodium Channels".
Below are MeSH descriptors whose meaning is more specific than "Epithelial Sodium Channels".
This graph shows the total number of publications written about "Epithelial Sodium Channels" by people in this website by year, and whether "Epithelial Sodium Channels" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 2 | 2 | 2004 | 0 | 1 | 1 | 2008 | 0 | 1 | 1 | 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epithelial Sodium Channels" by people in Profiles.
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Reisenauer MR, Anderson M, Huang L, Zhang Z, Zhou Q, Kone BC, Morris AP, Lesage GD, Dryer SE, Zhang W. AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha. J Biol Chem. 2009 Dec 18; 284(51):35659-69.
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Artunc F, Sandulache D, Nasir O, Boini KM, Friedrich B, Beier N, Dicks E, Pötzsch S, Klingel K, Amann K, Blazer-Yost BL, Scholz W, Risler T, Kuhl D, Lang F. Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARgamma agonist pioglitazone. Pflugers Arch. 2008 May; 456(2):425-36.
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Xie Y, Schafer JA. Inhibition of ENaC by intracellular Cl- in an MDCK clone with high ENaC expression. Am J Physiol Renal Physiol. 2004 Oct; 287(4):F722-31.
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Schafer JA. Abnormal regulation of ENaC: syndromes of salt retention and salt wasting by the collecting duct. Am J Physiol Renal Physiol. 2002 Aug; 283(2):F221-35.
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Morris RG, Schafer JA. cAMP increases density of ENaC subunits in the apical membrane of MDCK cells in direct proportion to amiloride-sensitive Na(+) transport. J Gen Physiol. 2002 Jul; 120(1):71-85.
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