Cathelicidins
"Cathelicidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes.
| Descriptor ID |
D054804
|
| MeSH Number(s) |
D12.644.050.099 D12.644.276.087.178 D12.776.467.087.407 D12.776.543.695.054.099 D23.529.087.470
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathelicidins".
Below are MeSH descriptors whose meaning is more specific than "Cathelicidins".
This graph shows the total number of publications written about "Cathelicidins" by people in this website by year, and whether "Cathelicidins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cathelicidins" by people in Profiles.
-
Kolar SS, Baidouri H, Hanlon S, McDermott AM. Protective role of murine ß-defensins 3 and 4 and cathelin-related antimicrobial peptide in Fusarium solani keratitis. Infect Immun. 2013 Aug; 81(8):2669-77.
-
Redfern RL, Patel N, Hanlon S, Farley W, Gondo M, Pflugfelder SC, McDermott AM. Toll-like receptor expression and activation in mice with experimental dry eye. Invest Ophthalmol Vis Sci. 2013 Feb 28; 54(2):1554-63.
-
Huang LC, Reins RY, Gallo RL, McDermott AM. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4498-508.