Polymyxins
"Polymyxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Basic lipopeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.
Descriptor ID |
D011113
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MeSH Number(s) |
D04.345.566.780 D10.477.750 D12.644.050.600 D12.644.641.780 D12.776.543.695.054.600
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polymyxins".
Below are MeSH descriptors whose meaning is more specific than "Polymyxins".
This graph shows the total number of publications written about "Polymyxins" by people in this website by year, and whether "Polymyxins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 | 2007 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2010 | 0 | 1 | 1 | 2013 | 2 | 0 | 2 | 2014 | 1 | 0 | 1 | 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymyxins" by people in Profiles.
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Abodakpi H, Gohlke J, Chang KT, Chow DS, Tam VH. Analytical and functional determination of polymyxin B protein binding in serum. Antimicrob Agents Chemother. 2015 Nov; 59(11):7121-3.
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Phe K, Lee Y, McDaneld PM, Prasad N, Yin T, Figueroa DA, Musick WL, Cottreau JM, Hu M, Tam VH. In vitro assessment and multicenter cohort study of comparative nephrotoxicity rates associated with colistimethate versus polymyxin B therapy. Antimicrob Agents Chemother. 2014 May; 58(5):2740-6.
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Kassamali Z, Rotschafer JC, Jones RN, Prince RA, Danziger LH. Reply to Nation et al. Clin Infect Dis. 2013 Dec; 57(11):1657-8.
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Kassamali Z, Rotschafer JC, Jones RN, Prince RA, Danziger LH. Polymyxins: wisdom does not always come with age. Clin Infect Dis. 2013 Sep; 57(6):877-83.
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Hirsch EB, Tam VH. Detection and treatment options for Klebsiella pneumoniae carbapenemases (KPCs): an emerging cause of multidrug-resistant infection. J Antimicrob Chemother. 2010 Jun; 65(6):1119-25.
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Kwa AL, Tam VH, Falagas ME. Polymyxins: a review of the current status including recent developments. Ann Acad Med Singapore. 2008 Oct; 37(10):870-83.
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Kwa AL, Lim TP, Low JG, Hou J, Kurup A, Prince RA, Tam VH. Pharmacokinetics of polymyxin B1 in patients with multidrug-resistant Gram-negative bacterial infections. Diagn Microbiol Infect Dis. 2008 Feb; 60(2):163-7.
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Falagas ME, Bliziotis IA, Tam VH. Intraventricular or intrathecal use of polymyxins in patients with Gram-negative meningitis: a systematic review of the available evidence. Int J Antimicrob Agents. 2007 Jan; 29(1):9-25.
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