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Muna Naash

TitleProfessor
InstitutionUniversity of Houston
DepartmentBiomedical Engineering
Address4800 Calhoun Rd
Houston TX 77004
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    Collapse Research 
    Collapse research activities and funding
    F32EY006330     (NAASH, MUNA I)Aug 20, 1991
    NIH/NEI
    MOUSE MODELS FOR RETINAL DEGENERATIONS
    Role: Principal Investigator
    R55EY010609     (NAASH, MUNA I)Sep 30, 1994 - Jul 31, 1995
    NIH/NEI
    PHOTORECEPTORS
    Role: Principal Investigator
    R56EY010609     (NAASH, MUNA I)Aug 1, 1995 - Aug 31, 2009
    NIH/NEI
    Mechanism of photoreceptor cell degeneration in animal models of retinal diseases
    Role: Principal Investigator
    R01EY010609     (NAASH, MUNA I)Aug 1, 1995 - Nov 30, 2019
    NIH/NEI
    Mechanism of photoreceptor cell degeneration in animal models of retinal disease
    Role: Principal Investigator
    R03EY016201     (NAASH, MUNA I)Sep 30, 2005 - Aug 31, 2008
    NIH/NEI
    Sustained, Non-viral Ocular Therapy Using Nanoparticles
    Role: Principal Investigator
    R01EY018656     (NAASH, MUNA I)Jan 1, 2008 - Jun 30, 2017
    NIH/NEI
    Compacted DNA Nanoparticles for Ocular Therapy
    Role: Principal Investigator
    R01EY022778     (NAASH, MUNA I)Sep 30, 2012 - Sep 29, 2015
    NIH/NEI
    DNA nanoparticle formulations for optimal ocular gene delivery
    Role: Principal Investigator
    R01EY026499     (NAASH, MUNA I)Feb 1, 2017 - Jan 31, 2020
    NIH/NEI
    Role of retbindin in retinal homeostasis and diseases
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Conley SM, Stuck MW, Watson JN, Naash MI. Rom1 converts Y141C-Prph2-associated pattern dystrophy to retinitis pigmentosa. Hum Mol Genet. 2017 Feb 01; 26(3):509-518. PMID: 28053051.
      View in: PubMed
    2. Chakraborty D, Conley SM, Zulliger R, Naash MI. The K153Del PRPH2 mutation differentially impacts photoreceptor structure and function. Hum Mol Genet. 2016 Aug 15; 25(16):3500-3514. PMID: 27365499.
      View in: PubMed
    3. Mitra RN, Nichols CA, Guo J, Makkia R, Cooper MJ, Naash MI, Han Z. Nanoparticle-mediated miR200-b delivery for the treatment of diabetic retinopathy. J Control Release. 2016 Aug 28; 236:31-7. PMID: 27297781.
      View in: PubMed
    4. Chakraborty D, Conley SM, Pittler SJ, Naash MI. Role of RDS and Rhodopsin in Cngb1-Related Retinal Degeneration. Invest Ophthalmol Vis Sci. 2016 Mar; 57(3):787-97. PMID: 26934134; PMCID: PMC4777275.
      View in: PubMed, PubMed Central
    5. Stuck MW, Conley SM, Naash MI. PRPH2/RDS and ROM-1: Historical context, current views and future considerations. Prog Retin Eye Res. 2016 05; 52:47-63. PMID: 26773759; PMCID: PMC4842342 [Available on 05/01/17].
      View in: PubMed, PubMed Central
    6. Stuck MW, Conley SM, Naash MI. RDS Functional Domains and Dysfunction in Disease. Adv Exp Med Biol. 2016; 854:217-22. PMID: 26427414.
      View in: PubMed
    7. Mitra RN, Conley SM, Naash MI. Therapeutic Approach of Nanotechnology for Oxidative Stress Induced Ocular Neurodegenerative Diseases. Adv Exp Med Biol. 2016; 854:463-9. PMID: 26427447.
      View in: PubMed
    8. Kelley RA, Al-Ubaidi MR, Naash MI. The Potential Role of Flavins and Retbindin in Retinal Function and Homeostasis. Adv Exp Med Biol. 2016; 854:643-8. PMID: 26427470.
      View in: PubMed
    9. Conley SM, Whalen P, Lewin AS, Naash MI. Characterization of Ribozymes Targeting a Congenital Night Blindness Mutation in Rhodopsin Mutation. Adv Exp Med Biol. 2016; 854:509-15. PMID: 26427453.
      View in: PubMed
    10. Chakraborty D, Conley SM, DeRamus ML, Pittler SJ, Naash MI. Varying the GARP2-to-RDS Ratio Leads to Defects in Rim Formation and Rod and Cone Function. Invest Ophthalmol Vis Sci. 2015 Dec; 56(13):8187-98. PMID: 26720471; PMCID: PMC4699412.
      View in: PubMed, PubMed Central
    11. Zulliger R, Conley SM, Naash MI. Non-viral therapeutic approaches to ocular diseases: An overview and future directions. J Control Release. 2015 Dec 10; 219:471-487. PMID: 26439665; PMCID: PMC4699668 [Available on 12/10/16].
      View in: PubMed, PubMed Central
    12. Stuck MW, Conley SM, Naash MI. Retinal Degeneration Slow (RDS) Glycosylation Plays a Role in Cone Function and in the Regulation of RDS·ROM-1 Protein Complex Formation. J Biol Chem. 2015 Nov 13; 290(46):27901-13. PMID: 26420485; PMCID: PMC4646032 [Available on 11/13/16].
      View in: PubMed, PubMed Central
    13. Zulliger R, Conley SM, Mwoyosvi ML, Stuck MW, Azadi S, Naash MI. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS One. 2015; 10(9):e0138508. PMID: 26406599; PMCID: PMC4583372.
      View in: PubMed, PubMed Central
    14. Orhan E, Dalkara D, Neuillé M, Lechauve C, Michiels C, Picaud S, Léveillard T, Sahel JA, Naash MI, Lavail MM, Zeitz C, Audo I. Genotypic and phenotypic characterization of P23H line 1 rat model. PLoS One. 2015; 10(5):e0127319. PMID: 26009893; PMCID: PMC4444340.
      View in: PubMed, PubMed Central
    15. Han Z, Banworth MJ, Makkia R, Conley SM, Al-Ubaidi MR, Cooper MJ, Naash MI. Genomic DNA nanoparticles rescue rhodopsin-associated retinitis pigmentosa phenotype. FASEB J. 2015 Jun; 29(6):2535-44. PMID: 25713057; PMCID: PMC4447225.
      View in: PubMed, PubMed Central
    16. Murray AR, Vuong L, Brobst D, Fliesler SJ, Peachey NS, Gorbatyuk MS, Naash MI, Al-Ubaidi MR. Glycosylation of rhodopsin is necessary for its stability and incorporation into photoreceptor outer segment discs. Hum Mol Genet. 2015 May 15; 24(10):2709-23. PMID: 25637522; PMCID: PMC4406288.
      View in: PubMed, PubMed Central
    17. Adijanto J, Naash MI. Nanoparticle-based technologies for retinal gene therapy. Eur J Pharm Biopharm. 2015 Sep; 95(Pt B):353-67. PMID: 25592325; PMCID: PMC4499495.
      View in: PubMed, PubMed Central
    18. Kelley RA, Al-Ubaidi MR, Naash MI. Retbindin is an extracellular riboflavin-binding protein found at the photoreceptor/retinal pigment epithelium interface. J Biol Chem. 2015 Feb 20; 290(8):5041-52. PMID: 25542898; PMCID: PMC4335240.
      View in: PubMed, PubMed Central
    19. Zulliger R, Naash MI, Rajala RV, Molday RS, Azadi S. Impaired association of retinal degeneration-3 with guanylate cyclase-1 and guanylate cyclase-activating protein-1 leads to leber congenital amaurosis-1. J Biol Chem. 2015 Feb 06; 290(6):3488-99. PMID: 25477517; PMCID: PMC4319016.
      View in: PubMed, PubMed Central
    20. Conley SM, Naash MI. Gene therapy for PRPH2-associated ocular disease: challenges and prospects. Cold Spring Harb Perspect Med. 2014 Aug 28; 4(11):a017376. PMID: 25167981.
      View in: PubMed
    21. Mitra RN, Merwin MJ, Han Z, Conley SM, Al-Ubaidi MR, Naash MI. Yttrium oxide nanoparticles prevent photoreceptor death in a light-damage model of retinal degeneration. Free Radic Biol Med. 2014 Oct; 75:140-8. PMID: 25066531; PMCID: PMC4171208.
      View in: PubMed, PubMed Central
    22. Stuck MW, Conley SM, Naash MI. The Y141C knockin mutation in RDS leads to complex phenotypes in the mouse. Hum Mol Genet. 2014 Dec 01; 23(23):6260-74. PMID: 25001182; PMCID: PMC4222364.
      View in: PubMed, PubMed Central
    23. Chakraborty D, Conley SM, Al-Ubaidi MR, Naash MI. Initiation of rod outer segment disc formation requires RDS. PLoS One. 2014; 9(6):e98939. PMID: 24897172; PMCID: PMC4045911.
      View in: PubMed, PubMed Central
    24. Rowe-Rendleman CL, Durazo SA, Kompella UB, Rittenhouse KD, Di Polo A, Weiner AL, Grossniklaus HE, Naash MI, Lewin AS, Horsager A, Edelhauser HF. Drug and gene delivery to the back of the eye: from bench to bedside. Invest Ophthalmol Vis Sci. 2014 Apr 28; 55(4):2714-30. PMID: 24777644; PMCID: PMC4004426.
      View in: PubMed, PubMed Central
    25. Conley SM, Al-Ubaidi MR, Han Z, Naash MI. Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins. FASEB J. 2014 Aug; 28(8):3468-79. PMID: 24736412; PMCID: PMC4101662.
      View in: PubMed, PubMed Central
    26. Kanan Y, Brobst D, Han Z, Naash MI, Al-Ubaidi MR. Fibulin 2, a tyrosine O-sulfated protein, is up-regulated following retinal detachment. J Biol Chem. 2014 May 09; 289(19):13419-33. PMID: 24692557; PMCID: PMC4036350.
      View in: PubMed, PubMed Central
    27. Kanan Y, Brobst D, Westmuckett AD, Moore KL, Han Z, Naash MI, Al-Ubaidi MR. WITHDRAWN: Fibulin 2, a tyrosine o-sulfated protein, is up-regulated following retinal detachment. J Biol Chem. 2014 Feb 26. PMID: 24446435.
      View in: PubMed
    28. Conley SM, Stuck MW, Burnett JL, Chakraborty D, Azadi S, Fliesler SJ, Naash MI. Insights into the mechanisms of macular degeneration associated with the R172W mutation in RDS. Hum Mol Genet. 2014 Jun 15; 23(12):3102-14. PMID: 24463884; PMCID: PMC4030767.
      View in: PubMed, PubMed Central
    29. Koirala A, Conley SM, Naash MI. Episomal maintenance of S/MAR-containing non-viral vectors for RPE-based diseases. Adv Exp Med Biol. 2014; 801:703-9. PMID: 24664761.
      View in: PubMed
    30. Han Z, Conley SM, Naash MI. Gene therapy for Stargardt disease associated with ABCA4 gene. Adv Exp Med Biol. 2014; 801:719-24. PMID: 24664763.
      View in: PubMed
    31. Stuck MW, Conley SM, Shaw RA, Wolf R, Naash MI. Electrophysiological characterization of rod and cone responses in the baboon nonhuman primate model. Adv Exp Med Biol. 2014; 801:67-73. PMID: 24664682.
      View in: PubMed
    32. Al-Ubaidi MR, Naash MI, Conley SM. A perspective on the role of the extracellular matrix in progressive retinal degenerative disorders. Invest Ophthalmol Vis Sci. 2013 Dec 17; 54(13):8119-24. PMID: 24346621; PMCID: PMC4587794.
      View in: PubMed, PubMed Central
    33. Mitra RN, Han Z, Merwin M, Al Taai M, Conley SM, Naash MI. Synthesis and characterization of glycol chitosan DNA nanoparticles for retinal gene delivery. ChemMedChem. 2014 Jan; 9(1):189-96. PMID: 24203490; PMCID: PMC4019313.
      View in: PubMed, PubMed Central
    34. Koirala A, Conley SM, Makkia R, Liu Z, Cooper MJ, Sparrow JR, Naash MI. Persistence of non-viral vector mediated RPE65 expression: case for viability as a gene transfer therapy for RPE-based diseases. J Control Release. 2013 Dec 28; 172(3):745-52. PMID: 24035979; PMCID: PMC3858392.
      View in: PubMed, PubMed Central
    35. Koirala A, Conley SM, Naash MI. A review of therapeutic prospects of non-viral gene therapy in the retinal pigment epithelium. Biomaterials. 2013 Sep; 34(29):7158-67. PMID: 23796578; PMCID: PMC3742069.
      View in: PubMed, PubMed Central
    36. Chakraborty D, Conley SM, Naash MI. Overexpression of retinal degeneration slow (RDS) protein adversely affects rods in the rd7 model of enhanced S-cone syndrome. PLoS One. 2013; 8(5):e63321. PMID: 23650562; PMCID: PMC3641132.
      View in: PubMed, PubMed Central
    37. Koirala A, Makkia RS, Conley SM, Cooper MJ, Naash MI. S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA. Hum Mol Genet. 2013 Apr 15; 22(8):1632-42. PMID: 23335596; PMCID: PMC3605833.
      View in: PubMed, PubMed Central
    38. Han Z, Guo J, Conley SM, Naash MI. Retinal angiogenesis in the Ins2(Akita) mouse model of diabetic retinopathy. Invest Ophthalmol Vis Sci. 2013 Jan 17; 54(1):574-84. PMID: 23221078; PMCID: PMC3558298.
      View in: PubMed, PubMed Central
    39. Han Z, Conley SM, Makkia R, Guo J, Cooper MJ, Naash MI. Comparative analysis of DNA nanoparticles and AAVs for ocular gene delivery. PLoS One. 2012; 7(12):e52189. PMID: 23272225; PMCID: PMC3525534.
      View in: PubMed, PubMed Central
    40. Chakraborty D, Rodgers KK, Conley SM, Naash MI. Structural characterization of the second intra-discal loop of the photoreceptor tetraspanin RDS. FEBS J. 2013 Jan; 280(1):127-38. PMID: 23121719; PMCID: PMC3652632.
      View in: PubMed, PubMed Central
    41. Han Z, Conley SM, Makkia RS, Cooper MJ, Naash MI. DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice. J Clin Invest. 2012 Sep; 122(9):3221-6. PMID: 22886305; PMCID: PMC3428101.
      View in: PubMed, PubMed Central
    42. Sherry DM, Kanan Y, Hamilton R, Hoffhines A, Arbogast KL, Fliesler SJ, Naash MI, Moore KL, Al-Ubaidi MR. Differential developmental deficits in retinal function in the absence of either protein tyrosine sulfotransferase-1 or -2. PLoS One. 2012; 7(6):e39702. PMID: 22745813; PMCID: PMC3382163.
      View in: PubMed, PubMed Central
    43. Stuck MW, Conley SM, Naash MI. Defects in the outer limiting membrane are associated with rosette development in the Nrl-/- retina. PLoS One. 2012; 7(3):e32484. PMID: 22427845; PMCID: PMC3299663.
      View in: PubMed, PubMed Central
    44. Han Z, Koirala A, Makkia R, Cooper MJ, Naash MI. Direct gene transfer with compacted DNA nanoparticles in retinal pigment epithelial cells: expression, repeat delivery and lack of toxicity. Nanomedicine (Lond). 2012 Apr; 7(4):521-39. PMID: 22356602; PMCID: PMC3404893.
      View in: PubMed, PubMed Central
    45. Conley SM, Chakraborty D, Naash MI. Mislocalization of oligomerization-incompetent RDS is associated with mislocalization of cone opsins and cone transducin. Adv Exp Med Biol. 2012; 723:657-62. PMID: 22183390.
      View in: PubMed
    46. Chakraborty D, Conley SM, Nash Z, Ding XQ, Naash MI. Overexpression of ROM-1 in the cone-dominant retina. Adv Exp Med Biol. 2012; 723:633-9. PMID: 22183387.
      View in: PubMed
    47. Macdonald IM, Naash MI, Ayyagari R. Retinal degenerations: genetics, mechanisms, and therapies. J Ophthalmol. 2011; 2011:764873. PMID: 22132314; PMCID: PMC3216361.
      View in: PubMed, PubMed Central
    48. Conley SM, Cai X, Makkia R, Wu Y, Sparrow JR, Naash MI. Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy. Biochim Biophys Acta. 2012 Jul; 1822(7):1169-79. PMID: 22033104; PMCID: PMC3351560.
      View in: PubMed, PubMed Central
    49. Koirala A, Makkia RS, Cooper MJ, Naash MI. Nanoparticle-mediated gene transfer specific to retinal pigment epithelial cells. Biomaterials. 2011 Dec; 32(35):9483-93. PMID: 21885113; PMCID: PMC3321842.
      View in: PubMed, PubMed Central
    50. Conley SM, Stuck MW, Naash MI. Structural and functional relationships between photoreceptor tetraspanins and other superfamily members. Cell Mol Life Sci. 2012 Apr; 69(7):1035-47. PMID: 21655915; PMCID: PMC3224198.
      View in: PubMed, PubMed Central
    51. Han Z, Conley SM, Naash MI. AAV and compacted DNA nanoparticles for the treatment of retinal disorders: challenges and future prospects. Invest Ophthalmol Vis Sci. 2011 May 10; 52(6):3051-9. PMID: 21558483; PMCID: PMC3109015.
      View in: PubMed, PubMed Central
    52. Chakraborty D, Conley SM, Stuck MW, Naash MI. Differences in RDS trafficking, assembly and function in cones versus rods: insights from studies of C150S-RDS. Hum Mol Genet. 2010 Dec 15; 19(24):4799-812. PMID: 20858597; PMCID: PMC2989890.
      View in: PubMed, PubMed Central
    53. Conley SM, Naash MI. Nanoparticles for retinal gene therapy. Prog Retin Eye Res. 2010 Sep; 29(5):376-97. PMID: 20452457; PMCID: PMC2907107.
      View in: PubMed, PubMed Central
    54. Cai X, Conley SM, Cheng T, Al-Ubaidi MR, Naash MI. A 350 bp region of the proximal promoter of Rds drives cell-type specific gene expression. Exp Eye Res. 2010 Aug; 91(2):186-94. PMID: 20447394; PMCID: PMC2937571.
      View in: PubMed, PubMed Central
    55. Conley SM, Stricker HM, Naash MI. Biochemical analysis of phenotypic diversity associated with mutations in codon 244 of the retinal degeneration slow gene. Biochemistry. 2010 Feb 09; 49(5):905-11. PMID: 20055437; PMCID: PMC2937569.
      View in: PubMed, PubMed Central
    56. Chakraborty D, Conley SM, Fliesler SJ, Naash MI. The function of oligomerization-incompetent RDS in rods. Adv Exp Med Biol. 2010; 664:39-46. PMID: 20238000; PMCID: PMC3161506.
      View in: PubMed, PubMed Central
    57. Conley SM, Ding XQ, Naash MI. RDS in cones does not interact with the beta subunit of the cyclic nucleotide gated channel. Adv Exp Med Biol. 2010; 664:63-70. PMID: 20238003; PMCID: PMC3161508.
      View in: PubMed, PubMed Central
    58. Cai X, Conley SM, Naash MI. Gene therapy in the Retinal Degeneration Slow model of retinitis pigmentosa. Adv Exp Med Biol. 2010; 664:611-9. PMID: 20238065; PMCID: PMC3161507.
      View in: PubMed, PubMed Central
    59. Cai X, Conley SM, Nash Z, Fliesler SJ, Cooper MJ, Naash MI. Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa. FASEB J. 2010 Apr; 24(4):1178-91. PMID: 19952284; PMCID: PMC2845431.
      View in: PubMed, PubMed Central
    60. Ding XQ, Quiambao AB, Fitzgerald JB, Cooper MJ, Conley SM, Naash MI. Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina. PLoS One. 2009 Oct 12; 4(10):e7410. PMID: 19823583; PMCID: PMC2756629.
      View in: PubMed, PubMed Central
    61. Cai X, Conley SM, Naash MI. RPE65: role in the visual cycle, human retinal disease, and gene therapy. Ophthalmic Genet. 2009 Jun; 30(2):57-62. PMID: 19373675; PMCID: PMC2821785.
      View in: PubMed, PubMed Central
    62. Cai X, Nash Z, Conley SM, Fliesler SJ, Cooper MJ, Naash MI. A partial structural and functional rescue of a retinitis pigmentosa model with compacted DNA nanoparticles. PLoS One. 2009; 4(4):e5290. PMID: 19390689; PMCID: PMC2669177.
      View in: PubMed, PubMed Central
    63. Conley SM, Naash MI. Focus on molecules: RDS. Exp Eye Res. 2009 Sep; 89(3):278-9. PMID: 19366620; PMCID: PMC2764256.
      View in: PubMed, PubMed Central
    64. Chakraborty D, Ding XQ, Conley SM, Fliesler SJ, Naash MI. Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus cones. Hum Mol Genet. 2009 Mar 01; 18(5):797-808. PMID: 19050038; PMCID: PMC2640204.
      View in: PubMed, PubMed Central
    65. Conley SM, Cai X, Naash MI. Nonviral ocular gene therapy: assessment and future directions. Curr Opin Mol Ther. 2008 Oct; 10(5):456-63. PMID: 18830921; PMCID: PMC2938038.
      View in: PubMed, PubMed Central
    66. Farjo R, Peterson WM, Naash MI. Expression profiling after retinal detachment and reattachment: a possible role for aquaporin-0. Invest Ophthalmol Vis Sci. 2008 Feb; 49(2):511-21. PMID: 18234993; PMCID: PMC2792233.
      View in: PubMed, PubMed Central
    67. Chakraborty D, Ding XQ, Fliesler SJ, Naash MI. Outer segment oligomerization of Rds: evidence from mouse models and subcellular fractionation. Biochemistry. 2008 Jan 29; 47(4):1144-56. PMID: 18171083; PMCID: PMC2788309.
      View in: PubMed, PubMed Central
    68. Nour M, Fliesler SJ, Naash MI. Genetic supplementation of RDS alleviates a loss-of-function phenotype in C214S model of retinitis pigmentosa. Adv Exp Med Biol. 2008; 613:129-38. PMID: 18188937; PMCID: PMC2789457.
      View in: PubMed, PubMed Central
    69. Chakraborty D, Whalen P, Lewin AS, Naash MI. In vitro analysis of ribozyme-mediated knockdown of an ADRP associated rhodopsin mutation. Adv Exp Med Biol. 2008; 613:97-106. PMID: 18188933; PMCID: PMC2793173.
      View in: PubMed, PubMed Central
    70. Conley S, Nour M, Fliesler SJ, Naash MI. Late-onset cone photoreceptor degeneration induced by R172W mutation in Rds and partial rescue by gene supplementation. Invest Ophthalmol Vis Sci. 2007 Dec; 48(12):5397-407. PMID: 18055786; PMCID: PMC2263142.
      View in: PubMed, PubMed Central
    71. Farjo R, Fliesler SJ, Naash MI. Effect of Rds abundance on cone outer segment morphogenesis, photoreceptor gene expression, and outer limiting membrane integrity. J Comp Neurol. 2007 Oct 20; 504(6):619-30. PMID: 17722028; PMCID: PMC2072815.
      View in: PubMed, PubMed Central
    72. Elliott MH, Nash ZA, Takemori N, Fliesler SJ, McClellan ME, Naash MI. Differential distribution of proteins and lipids in detergent-resistant and detergent-soluble domains in rod outer segment plasma membranes and disks. J Neurochem. 2008 Jan; 104(2):336-52. PMID: 17944869; PMCID: PMC2823591.
      View in: PubMed, PubMed Central
    73. Cai X, Conley S, Naash M. Nanoparticle applications in ocular gene therapy. Vision Res. 2008 Feb; 48(3):319-24. PMID: 17825344; PMCID: PMC2423345.
      View in: PubMed, PubMed Central
    74. Canola K, Angénieux B, Tekaya M, Quiambao A, Naash MI, Munier FL, Schorderet DF, Arsenijevic Y. Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate. Invest Ophthalmol Vis Sci. 2007 Jan; 48(1):446-54. PMID: 17197566; PMCID: PMC2823590.
      View in: PubMed, PubMed Central
    75. Farjo R, Skaggs J, Quiambao AB, Cooper MJ, Naash MI. Efficient non-viral ocular gene transfer with compacted DNA nanoparticles. PLoS One. 2006 Dec 20; 1:e38. PMID: 17183666; PMCID: PMC1762345.
      View in: PubMed, PubMed Central
    76. Farjo R, Naash MI. The role of Rds in outer segment morphogenesis and human retinal disease. Ophthalmic Genet. 2006 Dec; 27(4):117-22. PMID: 17148038.
      View in: PubMed
    77. Farjo R, Skaggs JS, Nagel BA, Quiambao AB, Nash ZA, Fliesler SJ, Naash MI. Retention of function without normal disc morphogenesis occurs in cone but not rod photoreceptors. J Cell Biol. 2006 Apr 10; 173(1):59-68. PMID: 16585269; PMCID: PMC2063789.
      View in: PubMed, PubMed Central
    78. Samardzija M, Wenzel A, Naash M, Remé CE, Grimm C. Rpe65 as a modifier gene for inherited retinal degeneration. Eur J Neurosci. 2006 Feb; 23(4):1028-34. PMID: 16519667; PMCID: PMC2823586.
      View in: PubMed, PubMed Central
    79. Nash ZA, Naash MI. Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin. Adv Exp Med Biol. 2006; 572:125-31. PMID: 17249565; PMCID: PMC2793175.
      View in: PubMed, PubMed Central
    80. Ding XQ, Naash MI. Transgenic animal studies of human retinal disease caused by mutations in peripherin/rds. Adv Exp Med Biol. 2006; 572:141-6. PMID: 17249567; PMCID: PMC2793174.
      View in: PubMed, PubMed Central
    81. Stricker HM, Ding XQ, Quiambao A, Fliesler SJ, Naash MI. The Cys214-->Ser mutation in peripherin/rds causes a loss-of-function phenotype in transgenic mice. Biochem J. 2005 Jun 01; 388(Pt 2):605-13. PMID: 15656787; PMCID: PMC1138968.
      View in: PubMed, PubMed Central
    82. Ding XQ, Stricker HM, Naash MI. Role of the second intradiscal loop of peripherin/rds in homo and hetero associations. Biochemistry. 2005 Mar 29; 44(12):4897-904. PMID: 15779916; PMCID: PMC2823589.
      View in: PubMed, PubMed Central
    83. Naash MI, Wu TH, Chakraborty D, Fliesler SJ, Ding XQ, Nour M, Peachey NS, Lem J, Qtaishat N, Al-Ubaidi MR, Ripps H. Retinal abnormalities associated with the G90D mutation in opsin. J Comp Neurol. 2004 Oct 11; 478(2):149-63. PMID: 15349976.
      View in: PubMed
    84. Nour M, Ding XQ, Stricker H, Fliesler SJ, Naash MI. Modulating expression of peripherin/rds in transgenic mice: critical levels and the effect of overexpression. Invest Ophthalmol Vis Sci. 2004 Aug; 45(8):2514-21. PMID: 15277471; PMCID: PMC2937570.
      View in: PubMed, PubMed Central
    85. Ding XQ, Nour M, Ritter LM, Goldberg AF, Fliesler SJ, Naash MI. The R172W mutation in peripherin/rds causes a cone-rod dystrophy in transgenic mice. Hum Mol Genet. 2004 Sep 15; 13(18):2075-87. PMID: 15254014.
      View in: PubMed
    86. Grimm C, Wenzel A, Stanescu D, Samardzija M, Hotop S, Groszer M, Naash M, Gassmann M, Remé C. Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration. J Neurosci. 2004 Jun 23; 24(25):5651-8. PMID: 15215287; PMCID: PMC2929919.
      View in: PubMed, PubMed Central
    87. Tan E, Ding XQ, Saadi A, Agarwal N, Naash MI, Al-Ubaidi MR. Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice. Invest Ophthalmol Vis Sci. 2004 Mar; 45(3):764-8. PMID: 14985288; PMCID: PMC2937568.
      View in: PubMed, PubMed Central
    88. Nour M, Quiambao AB, Al-Ubaidi MR, Naash MI. Absence of functional and structural abnormalities associated with expression of EGFP in the retina. Invest Ophthalmol Vis Sci. 2004 Jan; 45(1):15-22. PMID: 14691148; PMCID: PMC2937833.
      View in: PubMed, PubMed Central
    89. Nour M, Quiambao AB, Peterson WM, Al-Ubaidi MR, Naash MI. P2Y(2) receptor agonist INS37217 enhances functional recovery after detachment caused by subretinal injection in normal and rds mice. Invest Ophthalmol Vis Sci. 2003 Oct; 44(10):4505-14. PMID: 14507899; PMCID: PMC2937827.
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    90. Li C, Ding XQ, O'Brien J, Al-Ubaidi MR, Naash MI. Molecular characterization of the skate peripherin/rds gene: relationship to its orthologues and paralogues. Invest Ophthalmol Vis Sci. 2003 Jun; 44(6):2433-41. PMID: 12766040; PMCID: PMC2991160.
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    91. Nour M, Naash MI. Mouse models of human retinal disease caused by expression of mutant rhodopsin. A valuable tool for the assessment of novel gene therapies. Adv Exp Med Biol. 2003; 533:173-9. PMID: 15180262.
      View in: PubMed
    92. Naash MI, Ding XQ, Li C, O'Brien J, Al-Ubaidi MR. Peripherin/rds in skate retina. Adv Exp Med Biol. 2003; 533:377-83. PMID: 15180288.
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    93. Quiambao AB, Tan E, Chang S, Komori N, Naash MI, Peachey NS, Matsumoto H, Ucker DS, Al-Ubaidi MR. Transgenic Bcl-2 expressed in photoreceptor cells confers both death-sparing and death-inducing effects. Exp Eye Res. 2001 Nov; 73(5):711-21. PMID: 11747371.
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    94. Li C, Cheng M, Yang H, Peachey NS, Naash MI. Age-related changes in the mouse outer retina. Optom Vis Sci. 2001 Jun; 78(6):425-30. PMID: 11444632.
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    95. Ren JC, Stubbs EB, Matthes MT, Yasumura D, Naash MI, LaVail MM, Peachey NS. Retinal degeneration in the nervous mutant mouse. IV. Inner retinal changes. Exp Eye Res. 2001 Mar; 72(3):243-52. PMID: 11180973.
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    96. Tan E, Wang Q, Quiambao AB, Xu X, Qtaishat NM, Peachey NS, Lem J, Fliesler SJ, Pepperberg DR, Naash MI, Al-Ubaidi MR. The relationship between opsin overexpression and photoreceptor degeneration. Invest Ophthalmol Vis Sci. 2001 Mar; 42(3):589-600. PMID: 11222515.
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    97. Penn JS, Li S, Naash MI. Ambient hypoxia reverses retinal vascular attenuation in a transgenic mouse model of autosomal dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2000 Nov; 41(12):4007-13. PMID: 11053306.
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    98. Qtaishat NM, Okajima TI, Li S, Naash MI, Pepperberg DR. Retinoid kinetics in eye tissues of VPP transgenic mice and their normal littermates. Invest Ophthalmol Vis Sci. 1999 May; 40(6):1040-9. PMID: 10235537.
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    99. Wu TH, Ting TD, Okajima TI, Pepperberg DR, Ho YK, Ripps H, Naash MI. Opsin localization and rhodopsin photochemistry in a transgenic mouse model of retinitis pigmentosa. Neuroscience. 1998 Dec; 87(3):709-17. PMID: 9758235.
      View in: PubMed
    100. Cheng T, Peachey NS, Li S, Goto Y, Cao Y, Naash MI. The effect of peripherin/rds haploinsufficiency on rod and cone photoreceptors. J Neurosci. 1997 Nov 01; 17(21):8118-28. PMID: 9334387.
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    101. Naash MI, Al-Ubaidi MR, Anderson RE. Light exposure induces ubiquitin conjugation and degradation activities in the rat retina. Invest Ophthalmol Vis Sci. 1997 Oct; 38(11):2344-54. PMID: 9344358.
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    102. Liu X, Wu TH, Stowe S, Matsushita A, Arikawa K, Naash MI, Williams DS. Defective phototransductive disk membrane morphogenesis in transgenic mice expressing opsin with a mutated N-terminal domain. J Cell Sci. 1997 Oct; 110 ( Pt 20):2589-97. PMID: 9372448.
      View in: PubMed
    103. Cheng T, al Ubaidi MR, Naash MI. Structural and developmental analysis of the mouse peripherin/rds gene. Somat Cell Mol Genet. 1997 May; 23(3):165-83. PMID: 9330629.
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    104. Wang M, Lam TT, Tso MO, Naash MI. Expression of a mutant opsin gene increases the susceptibility of the retina to light damage. Vis Neurosci. 1997 Jan-Feb; 14(1):55-62. PMID: 9057268.
      View in: PubMed
    105. Naash MI, Ripps H, Li S, Goto Y, Peachey NS. Polygenic disease and retinitis pigmentosa: albinism exacerbates photoreceptor degeneration induced by the expression of a mutant opsin in transgenic mice. J Neurosci. 1996 Dec 15; 16(24):7853-8. PMID: 8987813.
      View in: PubMed
    106. Goto Y, Peachey NS, Ziroli NE, Seiple WH, Gryczan C, Pepperberg DR, Naash MI. Rod phototransduction in transgenic mice expressing a mutant opsin gene. J Opt Soc Am A Opt Image Sci Vis. 1996 Mar; 13(3):577-85. PMID: 8627415.
      View in: PubMed
    107. Goto Y, Peachey NS, Ripps H, Naash MI. Functional abnormalities in transgenic mice expressing a mutant rhodopsin gene. Invest Ophthalmol Vis Sci. 1995 Jan; 36(1):62-71. PMID: 7822160.
      View in: PubMed
    108. Peachey NS, Goto Y, al-Ubaidi MR, Naash MI. Properties of the mouse cone-mediated electroretinogram during light adaptation. Neurosci Lett. 1993 Nov 12; 162(1-2):9-11. PMID: 8121644.
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    109. Naash MI, Hollyfield JG, al-Ubaidi MR, Baehr W. Simulation of human autosomal dominant retinitis pigmentosa in transgenic mice expressing a mutated murine opsin gene. Proc Natl Acad Sci U S A. 1993 Jun 15; 90(12):5499-503. PMID: 8516292; PMCID: PMC46748.
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    110. Penn JS, Thum LA, Naash MI. Oxygen-induced retinopathy in the rat. Vitamins C and E as potential therapies. Invest Ophthalmol Vis Sci. 1992 May; 33(6):1836-45. PMID: 1582786.
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    111. Naash M, Izbicka E, Anderson RE. Rat retina has an active and stable ubiquitin-protein conjugating system. J Neurosci Res. 1991 Oct; 30(2):433-41. PMID: 1665870.
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    112. Penn JS, Thum LA, Naash MI. Photoreceptor physiology in the rat is governed by the light environment. Exp Eye Res. 1989 Aug; 49(2):205-15. PMID: 2767168.
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    113. Naash MI, Anderson RE. Glutathione-dependent enzymes in intact rod outer segments. Exp Eye Res. 1989 Feb; 48(2):309-18. PMID: 2924815.
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    114. Naash MI, LaVail MM, Anderson RE. Factors affecting the susceptibility of the retina to light damage. Prog Clin Biol Res. 1989; 314:513-22. PMID: 2608676.
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    115. Nielsen JC, Naash MI, Anderson RE. The regional distribution of vitamins E and C in mature and premature human retinas. Invest Ophthalmol Vis Sci. 1988 Jan; 29(1):22-6. PMID: 3335430.
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    116. Naash MI, Nielsen JC, Anderson RE. Regional distribution of glutathione peroxidase and Glutathione-S-transferase in adult and premature human retinas. Invest Ophthalmol Vis Sci. 1988 Jan; 29(1):149-52. PMID: 3335428.
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    117. Penn JS, Naash MI, Anderson RE. Effect of light history on retinal antioxidants and light damage susceptibility in the rat. Exp Eye Res. 1987 Jun; 44(6):779-88. PMID: 3653273.
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    118. Naash MI, Anderson RE. Characterization of glutathione peroxidase in frog retina. Curr Eye Res. 1984 Nov; 3(11):1299-304. PMID: 6334591.
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    119. Al-Mudhaffar SA, Naash M. Kinetics of alkaline phosphatase in serum of liver diseased, anemic and normal Iraqi individuals. Biochem Exp Biol. 1980; 16(2):141-55. PMID: 7348196.
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