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Don Coltart

TitleAssistant Professor
InstitutionUniversity of Houston
DepartmentChemistry
Address4800 Calhoun Rd
Houston TX 77004
Phone713-743-8762
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Rastelli EJ, Truong NT, Coltart DM. Asymmetric Induction in Hydroacylation by Cooperative Iminium Ion-Transition-Metal Catalysis. Org Lett. 2016 Nov 04; 18(21):5588-5591. PMID: 27767317.
      View in: PubMed
    2. Rastelli EJ, Coltart DM. Asymmetric Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride. J Org Chem. 2016 Oct 21; 81(20):9567-9575. PMID: 27657347.
      View in: PubMed
    3. Truong N, Sauer SJ, Seraphin-Hatcher C, Coltart DM. Direct carbon-carbon bond formation via reductive soft enolization: a syn-selective Mannich addition of a-iodo thioesters. Org Biomol Chem. 2016 Aug 16; 14(33):7864-8. PMID: 27492274.
      View in: PubMed
    4. Uteuliyev MM, Nguyen TT, Coltart DM. Diastereoselective addition of Grignard reagents to a-epoxy N-sulfonyl hydrazones. Nat Chem. 2015 Dec; 7(12):1024-7. PMID: 26587719.
      View in: PubMed
    5. Rastelli EJ, Coltart DM. A Concise and Highly Enantioselective Total Synthesis of (+)-anti- and (-)-syn-Mefloquine Hydrochloride: Definitive Absolute Stereochemical Assignment of the Mefloquines. Angew Chem Int Ed Engl. 2015 Nov 16; 54(47):14070-4. PMID: 26422780.
      View in: PubMed
    6. Knight JD, Coltart DM. Asymmetric anti-aldol addition of achiral ketones via chiral N-amino cyclic carbamate hydrazones. Chem Commun (Camb). 2013 Sep 04; 49(68):7495-7. PMID: 23873079.
      View in: PubMed
    7. Robertson BD, Wengryniuk SE, Coltart DM. Asymmetric total synthesis of apratoxin D. Org Lett. 2012 Oct 19; 14(20):5192-5. PMID: 23057680.
      View in: PubMed
    8. Hatcher JM, Kohler MC, Coltart DM. Catalytic asymmetric addition of thiols to nitrosoalkenes leading to chiral non-racemic a-sulfenyl ketones. Org Lett. 2011 Aug 05; 13(15):3810-3. PMID: 21714489.
      View in: PubMed
    9. Knight JD, Sauer SJ, Coltart DM. Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones. Org Lett. 2011 Jun 17; 13(12):3118-21. PMID: 21615091.
      View in: PubMed
    10. Wengryniuk SE, Lim D, Coltart DM. Regioselective asymmetric a,a-bisalkylation of ketones via complex-induced syn-deprotonation of chiral N-amino cyclic carbamate hydrazones. J Am Chem Soc. 2011 Jun 08; 133(22):8714-20. PMID: 21510644.
      View in: PubMed
    11. Garnsey MR, Matous JA, Kwiek JJ, Coltart DM. Asymmetric total synthesis of (+)- and (-)-clusianone and (+)- and (-)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity. Bioorg Med Chem Lett. 2011 Apr 15; 21(8):2406-9. PMID: 21414776; PMCID: PMC3070777.
      View in: PubMed, PubMed Central
    12. Krenske EH, Houk KN, Lim D, Wengryniuk SE, Coltart DM. Origins of stereoselectivity in the a-alkylation of chiral hydrazones. J Org Chem. 2010 Dec 17; 75(24):8578-84. PMID: 21070023; PMCID: PMC3005816.
      View in: PubMed, PubMed Central
    13. Garnsey MR, Lim D, Yost JM, Coltart DM. Development of a strategy for the asymmetric synthesis of polycyclic polyprenylated acylphloroglucinols via N-amino cyclic carbamate hydrazones: application to the total synthesis of (+)-clusianone. Org Lett. 2010 Nov 19; 12(22):5234-7. PMID: 20977254.
      View in: PubMed
    14. Yost JM, Alfie RJ, Tarsis EM, Chong I, Coltart DM. Direct carbon-carbon bond formation via soft enolization: aldol addition of a-halogenated thioesters. Chem Commun (Camb). 2011 Jan 07; 47(1):571-2. PMID: 20963247.
      View in: PubMed
    15. Sauer SJ, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via reductive soft enolization: a kinetically controlled syn-aldol addition of a-halo thioesters and enolizable aldehydes. J Am Chem Soc. 2010 Oct 13; 132(40):13997-9. PMID: 20849119.
      View in: PubMed
    16. Kohler MC, Yost JM, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via soft enolization: a biomimetic asymmetric Mannich reaction of phenylacetate thioesters. Org Lett. 2010 Aug 06; 12(15):3376-9. PMID: 20608684.
      View in: PubMed
    17. Hatcher JM, Coltart DM. Copper(I)-catalyzed addition of Grignard reagents to in situ-derived N-sulfonyl azoalkenes: an umpolung alkylation procedure applicable to the formation of up to three contiguous quaternary centers. J Am Chem Soc. 2010 Apr 07; 132(13):4546-7. PMID: 20232808.
      View in: PubMed
    18. Tarsis E, Gromova A, Lim D, Zhou G, Coltart DM. Overcoming the limitations of the Morita-Baylis-Hillman reaction: a rapid and general synthesis of alpha-alkenyl-beta'-hydroxy thioesters. Org Lett. 2008 Nov 06; 10(21):4819-22. PMID: 18844367.
      View in: PubMed
    19. Zhou G, Lim D, Coltart DM. Direct carbon-carbon bond formation via chemoselective soft enolization of thioesters: a remarkably simple and versatile crossed-Claisen reaction applied to the synthesis of LY294002. Org Lett. 2008 Sep 04; 10(17):3809-12. PMID: 18681454.
      View in: PubMed
    20. Lim D, Coltart DM. Simple and efficient asymmetric alpha-alkylation and alpha,alpha-bisalkylation of acyclic ketones by using chiral N-amino cyclic carbamate hydrazones. Angew Chem Int Ed Engl. 2008; 47(28):5207-10. PMID: 18528835.
      View in: PubMed
    21. Zhou G, Yost JM, Sauer SJ, Coltart DM. A facile and efficient anti-selective four-component direct aldol addition via chemoselective thioester enolate formation. Org Lett. 2007 Oct 25; 9(22):4663-5. PMID: 17902688.
      View in: PubMed
    22. Lim D, Fang F, Zhou G, Coltart DM. Direct carbon-carbon bond formation via soft enolization: a facile and efficient synthesis of 1,3-diketones. Org Lett. 2007 Oct 11; 9(21):4139-42. PMID: 17877360.
      View in: PubMed
    23. Yost JM, Zhou G, Coltart DM. A facile and efficient direct aldol addition of simple thioesters. Org Lett. 2006 Mar 30; 8(7):1503-6. PMID: 16562927.
      View in: PubMed
    24. Clive DL, Hisaindee S, Coltart DM. Derivatized amino acids relevant to native peptide synthesis by chemical ligation and acyl transfer. J Org Chem. 2003 Nov 28; 68(24):9247-54. PMID: 14629143.
      View in: PubMed
    25. Coltart DM, Danishefsky SJ. Novel synthetic approach to the 8,10-dimethyl anti-syn-anti-perhydrophenanthrene skeleton. Org Lett. 2003 Apr 17; 5(8):1289-92. PMID: 12688741.
      View in: PubMed
    26. Ragupathi G, Coltart DM, Williams LJ, Koide F, Kagan E, Allen J, Harris C, Glunz PW, Livingston PO, Danishefsky SJ. On the power of chemical synthesis: immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines. Proc Natl Acad Sci U S A. 2002 Oct 15; 99(21):13699-704. PMID: 12359877; PMCID: PMC129747.
      View in: PubMed, PubMed Central
    27. Coltart DM, Royyuru AK, Williams LJ, Glunz PW, Sames D, Kuduk SD, Schwarz JB, Chen XT, Danishefsky SJ, Live DH. Principles of mucin architecture: structural studies on synthetic glycopeptides bearing clustered mono-, di-, tri-, and hexasaccharide glycodomains. J Am Chem Soc. 2002 Aug 21; 124(33):9833-44. PMID: 12175243.
      View in: PubMed
    28. Ragupathi G, Deshpande PP, Coltart DM, Kim HM, Williams LJ, Danishefsky SJ, Livingston PO. Constructing an adenocarcinoma vaccine: immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Le(y) antibodies. Int J Cancer. 2002 May 10; 99(2):207-12. PMID: 11979435.
      View in: PubMed
    29. Clive DL, Coltart DM, Zhou Y. Synthesis of the Angiotensin-Converting Enzyme Inhibitors (-)-A58365A and (-)-A58365B from a Common Intermediate. J Org Chem. 1999 Mar 05; 64(5):1447-1454. PMID: 11674202.
      View in: PubMed
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