 Hydrazones
"Hydrazones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Descriptor ID |
D006835
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| MeSH Number(s) |
D02.442.288
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydrazones".
Below are MeSH descriptors whose meaning is more specific than "Hydrazones".
This graph shows the total number of publications written about "Hydrazones" by people in this website by year, and whether "Hydrazones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 2 | 1 | 3 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hydrazones" by people in Profiles.
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Le PQ, May JA. Hydrazone-initiated carbene/alkyne cascades to form polycyclic products: ring-fused cyclopropenes as mechanistic intermediates. J Am Chem Soc. 2015 Sep 30; 137(38):12219-22.
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Knight JD, Coltart DM. Asymmetric anti-aldol addition of achiral ketones via chiral N-amino cyclic carbamate hydrazones. Chem Commun (Camb). 2013 Sep 04; 49(68):7495-7.
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Knight JD, Sauer SJ, Coltart DM. Asymmetric total synthesis of the antimalarial drug (+)-mefloquine hydrochloride via chiral N-amino cyclic carbamate hydrazones. Org Lett. 2011 Jun 17; 13(12):3118-21.
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Moldovan CM, Oniga O, Pârvu A, Tiperciuc B, Verite P, Pîrnau A, Crisan O, Bojita M, Pop R. Synthesis and anti-inflammatory evaluation of some new acyl-hydrazones bearing 2-aryl-thiazole. Eur J Med Chem. 2011 Feb; 46(2):526-34.
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Krenske EH, Houk KN, Lim D, Wengryniuk SE, Coltart DM. Origins of stereoselectivity in the a-alkylation of chiral hydrazones. J Org Chem. 2010 Dec 17; 75(24):8578-84.
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Garnsey MR, Lim D, Yost JM, Coltart DM. Development of a strategy for the asymmetric synthesis of polycyclic polyprenylated acylphloroglucinols via N-amino cyclic carbamate hydrazones: application to the total synthesis of (+)-clusianone. Org Lett. 2010 Nov 19; 12(22):5234-7.
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Ragan CI, Widger WR. The reconstitution of the mitochondrial energy-linked transhydrogenase. Biochem Biophys Res Commun. 1975 Feb 03; 62(3):744-9.
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