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Alexander A Oraevsky

TitleAdjunct Professor
InstitutionUniversity of Houston
DepartmentBiomedical Engineering
Address4800 Calhoun Rd
Houston TX 77004
Phone713-270-5393
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    Collapse Research 
    Collapse research activities and funding
    R29CA080221     (ORAEVSKY, ALEXANDER A)May 22, 1998 - Apr 30, 2005
    NIH/NCI
    CLINICAL LASER OPTOACOUSTIC SYSTEM FOR BREAST CANCER
    Role: Principal Investigator
    R03TW005776     (ORAEVSKY, ALEXANDER A)Dec 14, 2001 - Nov 30, 2004
    NIH/FIC
    Feasibility of optoacoustic tomography in backward mode
    Role: Principal Investigator
    R33CA095883     (ORAEVSKY, ALEXANDER A)Jul 9, 2002 - Jun 30, 2006
    NIH/NCI
    Diagnostic Imaging of Blood in Breast Tumor Angiogenesis
    Role: Principal Investigator
    R44CA096153     (ORAEVSKY, ALEXANDER A)Sep 30, 2002 - Apr 30, 2010
    NIH/NCI
    Optoacoustic system for image-guided biopsy of prostate cancer
    Role: Principal Investigator
    R44CA110137     (ORAEVSKY, ALEXANDER A)Sep 1, 2005 - Apr 30, 2013
    NIH/NCI
    Optoacoustic imaging enhanced by gold nanorods
    Role: Principal Investigator
    R44CA128196     (ORAEVSKY, ALEXANDER A)Sep 27, 2007 - Aug 31, 2014
    NIH/NCI
    3D Hybrid Optoacoustic-Ultrasonic System for Diagnostic Imaging of Breast Cancer
    Role: Principal Investigator
    R43ES021629     (ORAEVSKY, ALEXANDER A)Sep 21, 2011 - Feb 28, 2012
    NIH/NIEHS
    Optoacoustic system for monitoring biodistribution of nanoparticles in vivo.
    Role: Principal Investigator
    R01CA167446     (ORAEVSKY, ALEXANDER A)May 1, 2012 - Mar 31, 2017
    NIH/NCI
    Multimode laser optoacoustic tomography system for breast cancer care
    Role: Principal Investigator
    R43EB015287     (ORAEVSKY, ALEXANDER A)May 8, 2012 - Jun 30, 2013
    NIH/NIBIB
    Laser Ultrasound and Optoacoustic Endoscopy of Esophagus
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Longo DL, Stefania R, Aime S, Oraevsky A. Melanin-Based Contrast Agents for Biomedical Optoacoustic Imaging and Theranostic Applications. Int J Mol Sci. 2017 Aug 07; 18(8). PMID: 28783106.
      View in: PubMed
    2. Lou Y, Wang K, Oraevsky AA, Anastasio MA. Impact of nonstationary optical illumination on image reconstruction in optoacoustic tomography. J Opt Soc Am A Opt Image Sci Vis. 2016 Dec 01; 33(12):2333-2347. PMID: 27906261.
      View in: PubMed
    3. Maswadi SM, Ibey BL, Roth CC, Tsyboulski DA, Beier HT, Glickman RD, Oraevsky AA. All-optical optoacoustic microscopy based on probe beam deflection technique. Photoacoustics. 2016 Sep; 4(3):91-101. PMID: 27761408.
      View in: PubMed
    4. Ermilov SA, Su R, Conjusteau A, Anis F, Nadvoretskiy V, Anastasio MA, Oraevsky AA. Three-Dimensional Optoacoustic and Laser-Induced Ultrasound Tomography System for Preclinical Research in Mice: Design and Phantom Validation. Ultrason Imaging. 2016 Jan; 38(1):77-95. PMID: 26088582.
      View in: PubMed
    5. Liopo A, Su R, Oraevsky AA. Melanin nanoparticles as a novel contrast agent for optoacoustic tomography. Photoacoustics. 2015 Mar; 3(1):35-43. PMID: 25893172; PMCID: PMC4398798.
      View in: PubMed, PubMed Central
    6. Oraevsky AA. "Contrast agents for optoacoustic imaging: design and biomedical applications". Photoacoustics. 2015 Mar; 3(1):1-2. PMID: 25893168; PMCID: PMC4398807.
      View in: PubMed, PubMed Central
    7. Petrova EV, Oraevsky AA, Ermilov SA. Red blood cell as a universal optoacoustic sensor for non-invasive temperature monitoring. Appl Phys Lett. 2014 Sep 01; 105(9):094103. PMID: 25316928.
      View in: PubMed
    8. Wang K, Schoonover RW, Su R, Oraevsky A, Anastasio MA. Discrete imaging models for three-dimensional optoacoustic tomography using radially symmetric expansion functions. IEEE Trans Med Imaging. 2014 May; 33(5):1180-93. PMID: 24770921; PMCID: PMC4374808.
      View in: PubMed, PubMed Central
    9. Petrova E, Ermilov S, Su R, Nadvoretskiy V, Conjusteau A, Oraevsky A. Using optoacoustic imaging for measuring the temperature dependence of Grüneisen parameter in optically absorbing solutions. Opt Express. 2013 Oct 21; 21(21):25077-90. PMID: 24150350; PMCID: PMC3867102.
      View in: PubMed, PubMed Central
    10. Su R, Ermilov S, Liopo A, Oraevsky A. Laser OptoAcoustic Tomography: Towards New Technology for Biomedical Diagnostics. Nucl Instrum Methods Phys Res A. 2013 Aug 21; 720:58-61. PMID: 25210212.
      View in: PubMed
    11. Tsyboulski DA, Liopo AV, Su R, Ermilov SA, Bachilo SM, Weisman RB, Oraevsky AA. Enabling in vivo measurements of nanoparticle concentrations with three-dimensional optoacoustic tomography. J Biophotonics. 2014 Aug; 7(8):581-8. PMID: 23554158; PMCID: PMC4153368.
      View in: PubMed, PubMed Central
    12. Wang K, Huang C, Kao YJ, Chou CY, Oraevsky AA, Anastasio MA. Accelerating image reconstruction in three-dimensional optoacoustic tomography on graphics processing units. Med Phys. 2013 Feb; 40(2):023301. PMID: 23387778; PMCID: PMC3581128.
      View in: PubMed, PubMed Central
    13. Su R, Ermilov SA, Liopo AV, Oraevsky AA. Three-dimensional optoacoustic imaging as a new noninvasive technique to study long-term biodistribution of optical contrast agents in small animal models. J Biomed Opt. 2012 Oct; 17(10):101506. PMID: 23223982; PMCID: PMC3380408.
      View in: PubMed, PubMed Central
    14. Liopo A, Conjusteau A, Tsyboulski D, Ermolinsky B, Kazansky A, Oraevsky A. Biocompatible Gold Nanorod Conjugates for Preclinical Biomedical Research. J Nanomed Nanotechnol. 2012 Aug 03; S2. PMID: 23264890.
      View in: PubMed
    15. Wang K, Su R, Oraevsky AA, Anastasio MA. Investigation of iterative image reconstruction in three-dimensional optoacoustic tomography. Phys Med Biol. 2012 Sep 07; 57(17):5399-423. PMID: 22864062; PMCID: PMC3532927.
      View in: PubMed, PubMed Central
    16. Liopo AV, Conjusteau A, Chumakova OV, Ermilov SA, Su R, Oraevsky AA. Highly purified biocompatible gold nanorods for contrasted optoacoustic imaging of small animal models. Nanosci Nanotechnol Lett. 2012 Jul; 4(7):681-686. PMID: 23050035.
      View in: PubMed
    17. Liopo AV, Conjusteau A, Konopleva M, Andreeff M, Oraevsky AA. Laser nanothermolysis of human leukemia cells using functionalized plasmonic nanoparticles. Nano Biomed Eng. 2012; 4(2):66-75. PMID: 22720194.
      View in: PubMed
    18. Lamela H, Gallego D, Gutierrez R, Oraevsky A. Interferometric fiber optic sensors for biomedical applications of optoacoustic imaging. J Biophotonics. 2011 Mar; 4(3):184-92. PMID: 21246745.
      View in: PubMed
    19. Wang K, Ermilov SA, Su R, Brecht HP, Oraevsky AA, Anastasio MA. An imaging model incorporating ultrasonic transducer properties for three-dimensional optoacoustic tomography. IEEE Trans Med Imaging. 2011 Feb; 30(2):203-14. PMID: 20813634; PMCID: PMC3033994.
      View in: PubMed, PubMed Central
    20. Fronheiser MP, Ermilov SA, Brecht HP, Conjusteau A, Su R, Mehta K, Oraevsky AA. Real-time optoacoustic monitoring and three-dimensional mapping of a human arm vasculature. J Biomed Opt. 2010 Mar-Apr; 15(2):021305. PMID: 20459227; PMCID: PMC2859082.
      View in: PubMed, PubMed Central
    21. Yaseen MA, Ermilov SA, Brecht HP, Su R, Conjusteau A, Fronheiser M, Bell BA, Motamedi M, Oraevsky AA. Optoacoustic imaging of the prostate: development toward image-guided biopsy. J Biomed Opt. 2010 Mar-Apr; 15(2):021310. PMID: 20459232; PMCID: PMC2917450.
      View in: PubMed, PubMed Central
    22. Wang LV, Oraevsky AA. Special section guest editorial: Photons plus ultrasound: imaging and sensing. J Biomed Opt. 2010 Mar-Apr; 15(2):021301. PMID: 20459223.
      View in: PubMed
    23. Chitnis PV, Brecht HP, Su R, Oraevsky AA. Feasibility of optoacoustic visualization of high-intensity focused ultrasound-induced thermal lesions in live tissue. J Biomed Opt. 2010 Mar-Apr; 15(2):021313. PMID: 20459235; PMCID: PMC2850587.
      View in: PubMed, PubMed Central
    24. Lu W, Huang Q, Ku G, Wen X, Zhou M, Guzatov D, Brecht P, Su R, Oraevsky A, Wang LV, Li C. Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres. Biomaterials. 2010 Mar; 31(9):2617-26. PMID: 20036000; PMCID: PMC2813997.
      View in: PubMed, PubMed Central
    25. Lamela H, Gallego D, Oraevsky A. Optoacoustic imaging using fiber-optic interferometric sensors. Opt Lett. 2009 Dec 01; 34(23):3695-7. PMID: 19953165.
      View in: PubMed
    26. Brecht HP, Su R, Fronheiser M, Ermilov SA, Conjusteau A, Oraevsky AA. Whole-body three-dimensional optoacoustic tomography system for small animals. J Biomed Opt. 2009 Nov-Dec; 14(6):064007. PMID: 20059245; PMCID: PMC2794413.
      View in: PubMed, PubMed Central
    27. Conjusteau A, Ermilov SA, Su R, Brecht HP, Fronheiser MP, Oraevsky AA. Measurement of the spectral directivity of optoacoustic and ultrasonic transducers with a laser ultrasonic source. Rev Sci Instrum. 2009 Sep; 80(9):093708. PMID: 19791945; PMCID: PMC2766411.
      View in: PubMed, PubMed Central
    28. Ermilov SA, Khamapirad T, Conjusteau A, Leonard MH, Lacewell R, Mehta K, Miller T, Oraevsky AA. Laser optoacoustic imaging system for detection of breast cancer. J Biomed Opt. 2009 Mar-Apr; 14(2):024007. PMID: 19405737.
      View in: PubMed
    29. Egerev S, Ermilov S, Ovchinnikov O, Fokin A, Guzatov D, Klimov V, Kanavin A, Oraevsky A. Acoustic signals generated by laser-irradiated metal nanoparticles. Appl Opt. 2009 Mar 01; 48(7):C38-45. PMID: 19252614.
      View in: PubMed
    30. Eghtedari M, Liopo AV, Copland JA, Oraevsky AA, Motamedi M. Engineering of hetero-functional gold nanorods for the in vivo molecular targeting of breast cancer cells. Nano Lett. 2009 Jan; 9(1):287-91. PMID: 19072129; PMCID: PMC4153361.
      View in: PubMed, PubMed Central
    31. Eghtedari M, Oraevsky A, Copland JA, Kotov NA, Conjusteau A, Motamedi M. High sensitivity of in vivo detection of gold nanorods using a laser optoacoustic imaging system. Nano Lett. 2007 Jul; 7(7):1914-8. PMID: 17570730.
      View in: PubMed
    32. Lapotko DO, Lukianova-Hleb EY, Oraevsky AA. Clusterization of nanoparticles during their interaction with living cells. Nanomedicine (Lond). 2007 Apr; 2(2):241-53. PMID: 17716124.
      View in: PubMed
    33. Lapotko DO, Lukianova E, Oraevsky AA. Selective laser nano-thermolysis of human leukemia cells with microbubbles generated around clusters of gold nanoparticles. Lasers Surg Med. 2006 Jul; 38(6):631-42. PMID: 16736503.
      View in: PubMed
    34. Lapotko D, Lukianova E, Potapnev M, Aleinikova O, Oraevsky A. Method of laser activated nano-thermolysis for elimination of tumor cells. Cancer Lett. 2006 Jul 28; 239(1):36-45. PMID: 16202512.
      View in: PubMed
    35. Spirou GM, Oraevsky AA, Vitkin IA, Whelan WM. Optical and acoustic properties at 1064 nm of polyvinyl chloride-plastisol for use as a tissue phantom in biomedical optoacoustics. Phys Med Biol. 2005 Jul 21; 50(14):N141-53. PMID: 16177502.
      View in: PubMed
    36. Copland JA, Eghtedari M, Popov VL, Kotov N, Mamedova N, Motamedi M, Oraevsky AA. Bioconjugated gold nanoparticles as a molecular based contrast agent: implications for imaging of deep tumors using optoacoustic tomography. Mol Imaging Biol. 2004 Sep-Oct; 6(5):341-9. PMID: 15380744.
      View in: PubMed
    37. Andreev VG, Karabutov AA, Oraevsky AA. Detection of ultrawide-band ultrasound pulses in optoacoustic tomography. IEEE Trans Ultrason Ferroelectr Freq Control. 2003 Oct; 50(10):1383-90. PMID: 14609079.
      View in: PubMed
    38. Oraevsky AA, Jacques SL, Tittel FK. Measurement of tissue optical properties by time-resolved detection of laser-induced transient stress. Appl Opt. 1997 Jan 01; 36(1):402-15. PMID: 18250688.
      View in: PubMed
    39. Oraevsky AA, Jacques SL, Esenaliev RO, Tittel FK. Pulsed laser ablation of soft tissues, gels, and aqueous solutions at temperatures below 100 degrees C. Lasers Surg Med. 1996; 18(3):231-40. PMID: 8778517.
      View in: PubMed
    40. Oraevsky AA, Jacques SL, Pettit GH, Tittel FK, Henry PD. XeCl laser ablation of atherosclerotic aorta: luminescence spectroscopy of ablation products. Lasers Surg Med. 1993; 13(2):168-78. PMID: 8464302.
      View in: PubMed
    41. Esenaliev RO, Oraevsky AA, Letokhov VS, Karabutov AA, Malinsky TV. Studies of acoustical and shock waves in the pulsed laser ablation of biotissue. Lasers Surg Med. 1993; 13(4):470-84. PMID: 8366748.
      View in: PubMed
    42. Oraevsky AA, Jacques SL, Pettit GH, Sauerbrey RA, Tittel FK, Nguy JH, Henry PD. XeCl laser-induced fluorescence of atherosclerotic arteries. Spectral similarities between lipid-rich lesions and peroxidized lipoproteins. Circ Res. 1993 Jan; 72(1):84-90. PMID: 8417849.
      View in: PubMed
    43. Oraevsky AA, Jacques SL, Pettit GH, Saidi IS, Tittel FK, Henry PD. XeCl laser ablation of atherosclerotic aorta: optical properties and energy pathways. Lasers Surg Med. 1992; 12(6):585-97. PMID: 1453859.
      View in: PubMed
    44. Balaban P, Esenaliev R, Karu T, Kutomkina E, Letokhov V, Oraevsky A, Ovcharenko N. He-Ne laser irradiation of single identified neurons. Lasers Surg Med. 1992; 12(3):329-37. PMID: 1508029.
      View in: PubMed
    45. Esenaliev RO, Oraevsky AA, Letokhov VS. Laser ablation of atherosclerotic blood vessel tissue under various irradiation conditions. IEEE Trans Biomed Eng. 1989 Dec; 36(12):1188-94. PMID: 2606494.
      View in: PubMed
    46. Dobrov EN, Arbieva ZKh, Timofeeva EK, Esenaliev RO, Oraevsky AA, Nikogosyan DN. UV laser induced RNA-protein crosslinks and RNA chain breaks in tobacco mosaic virus RNA in situ. Photochem Photobiol. 1989 May; 49(5):595-8. PMID: 2755995.
      View in: PubMed
    47. Nikogosyan DN, Angelov DA, Oraevsky AA. Determination of parameters of excited states of DNA and RNA bases by laser UV photolysis. Photochem Photobiol. 1982 May; 35(5):627-35. PMID: 6178121.
      View in: PubMed
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