Alanine Racemase
"Alanine Racemase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyridoxal-phosphate protein that reversibly catalyzes the conversion of L-alanine to D-alanine. EC 5.1.1.1.
| Descriptor ID |
D000411
|
| MeSH Number(s) |
D08.811.399.894.200.200
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alanine Racemase".
Below are MeSH descriptors whose meaning is more specific than "Alanine Racemase".
This graph shows the total number of publications written about "Alanine Racemase" by people in this website by year, and whether "Alanine Racemase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alanine Racemase" by people in Profiles.
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Huang HC, Jupiter D, Qiu M, Briggs JM, Vanburen V. Cluster analysis of hydration waters around the active sites of bacterial alanine racemase using a 2-ns MD simulation. Biopolymers. 2008 Mar; 89(3):210-9.
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LeMagueres P, Im H, Ebalunode J, Strych U, Benedik MJ, Briggs JM, Kohn H, Krause KL. The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry. 2005 Feb 08; 44(5):1471-81.
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Mustata G, Briggs JM. Cluster analysis of water molecules in alanine racemase and their putative structural role. Protein Eng Des Sel. 2004 Mar; 17(3):223-34.
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Mustata GI, Soares TA, Briggs JM. Molecular dynamics studies of alanine racemase: a structural model for drug design. Biopolymers. 2003 Oct; 70(2):186-200.
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Mustata GI, Briggs JM. A structure-based design approach for the identification of novel inhibitors: application to an alanine racemase. J Comput Aided Mol Des. 2002 Dec; 16(12):935-53.
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Ondrechen MJ, Briggs JM, McCammon JA. A model for enzyme-substrate interaction in alanine racemase. J Am Chem Soc. 2001 Mar 28; 123(12):2830-4.