Alzheimer Disease
"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Descriptor ID |
D000544
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MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
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Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Disease, Alzheimer
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Syndrome, Alzheimer
- Alzheimer Dementia (AD)
- Dementia, Alzheimer (AD)
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Primary Senile Degenerative Dementia
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Senile Dementia, Alzheimer Type
- Alzheimer Type Senile Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer's Disease
- Disease, Alzheimer's
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Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1985 | 1 | 0 | 1 | 1986 | 1 | 1 | 2 | 1987 | 1 | 0 | 1 | 1992 | 2 | 1 | 3 | 1994 | 0 | 1 | 1 | 1995 | 1 | 0 | 1 | 1996 | 2 | 0 | 2 | 1997 | 2 | 0 | 2 | 1998 | 2 | 0 | 2 | 1999 | 3 | 0 | 3 | 2001 | 3 | 0 | 3 | 2002 | 5 | 0 | 5 | 2003 | 2 | 0 | 2 | 2004 | 3 | 0 | 3 | 2005 | 4 | 1 | 5 | 2006 | 3 | 0 | 3 | 2007 | 1 | 0 | 1 | 2008 | 3 | 1 | 4 | 2009 | 5 | 0 | 5 | 2010 | 3 | 1 | 4 | 2011 | 4 | 1 | 5 | 2012 | 3 | 2 | 5 | 2013 | 5 | 1 | 6 | 2014 | 6 | 0 | 6 | 2015 | 2 | 0 | 2 | 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Perez C, Ziburkus J, Ullah G. Analyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer's Disease. PLoS One. 2016; 11(12):e0168800.
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Alverson WA, Massman PJ, Doody RS. Prevalence and correlates of cognitive asymmetry in a large sample of Alzheimer's disease patients. J Clin Exp Neuropsychol. 2016; 38(5):516-26.
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Maestri M, Carnicelli L, Tognoni G, Di Coscio E, Giorgi FS, Volpi L, Economou NT, Ktonas P, Ferri R, Bonuccelli U, Bonanni E. Non-rapid eye movement sleep instability in mild cognitive impairment: a pilot study. Sleep Med. 2015 Sep; 16(9):1139-45.
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Takahashi K, Kong Q, Lin Y, Stouffer N, Schulte DA, Lai L, Liu Q, Chang LC, Dominguez S, Xing X, Cuny GD, Hodgetts KJ, Glicksman MA, Lin CL. Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease. J Exp Med. 2015 Mar 09; 212(3):319-32.
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Dao AT, Zagaar MA, Alkadhi KA. Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer's Disease. Mol Neurobiol. 2015 Dec; 52(3):1067-1076.
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Alkadhi KA, Tran TT. Chronic psychosocial stress impairs early LTP but not late LTP in the dentate gyrus of at-risk rat model of Alzheimer's disease. Brain Res. 2014 Nov 07; 1588:150-8.
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Alkadhi KA, Tran TT. Chronic Stress Decreases Basal Levels of Memory-Related Signaling Molecules in Area CA1 of At-Risk (Subclinical) Model of Alzheimer's Disease. Mol Neurobiol. 2015 Aug; 52(1):93-100.
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Xu J, Chatterjee M, Baguley TD, Brouillette J, Kurup P, Ghosh D, Kanyo J, Zhang Y, Seyb K, Ononenyi C, Foscue E, Anderson GM, Gresack J, Cuny GD, Glicksman MA, Greengard P, Lam TT, Tautz L, Nairn AC, Ellman JA, Lombroso PJ. Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease. PLoS Biol. 2014 Aug; 12(8):e1001923.
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Seidl JN, Massman PJ. Relationships between testosterone levels and cognition in patients with Alzheimer disease and nondemented elderly men. J Geriatr Psychiatry Neurol. 2015 Mar; 28(1):27-39.
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Bonakis A, Economou NT, Paparrigopoulos T, Bonanni E, Maestri M, Carnicelli L, Di Coscio E, Ktonas P, Vagiakis E, Theodoropoulos P, Papageorgiou SG. Sleep in frontotemporal dementia is equally or possibly more disrupted, and at an earlier stage, when compared to sleep in Alzheimer's disease. J Alzheimers Dis. 2014; 38(1):85-91.
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