 Cryptosporidiosis
"Cryptosporidiosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intestinal infection with organisms of the genus CRYPTOSPORIDIUM. It occurs in both animals and humans. Symptoms include severe DIARRHEA.
| Descriptor ID |
D003457
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| MeSH Number(s) |
C03.432.269 C03.701.688.235 C03.752.250.269 C03.752.625.235 C06.405.469.452.269 C22.674.710.235
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cryptosporidiosis".
Below are MeSH descriptors whose meaning is more specific than "Cryptosporidiosis".
This graph shows the total number of publications written about "Cryptosporidiosis" by people in this website by year, and whether "Cryptosporidiosis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cryptosporidiosis" by people in Profiles.
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Gorla SK, McNair NN, Yang G, Gao S, Hu M, Jala VR, Haribabu B, Striepen B, Cuny GD, Mead JR, Hedstrom L. Validation of IMP dehydrogenase inhibitors in a mouse model of cryptosporidiosis. Antimicrob Agents Chemother. 2014; 58(3):1603-14.
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Johnson CR, Gorla SK, Kavitha M, Zhang M, Liu X, Striepen B, Mead JR, Cuny GD, Hedstrom L. Phthalazinone inhibitors of inosine-5'-monophosphate dehydrogenase from Cryptosporidium parvum. Bioorg Med Chem Lett. 2013 Feb 15; 23(4):1004-7.
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Kirubakaran S, Gorla SK, Sharling L, Zhang M, Liu X, Ray SS, Macpherson IS, Striepen B, Hedstrom L, Cuny GD. Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH. Bioorg Med Chem Lett. 2012 Mar 01; 22(5):1985-8.
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Macpherson IS, Kirubakaran S, Gorla SK, Riera TV, D'Aquino JA, Zhang M, Cuny GD, Hedstrom L. The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity. J Am Chem Soc. 2010 Feb 03; 132(4):1230-1.
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Maurya SK, Gollapalli DR, Kirubakaran S, Zhang M, Johnson CR, Benjamin NN, Hedstrom L, Cuny GD. Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem. 2009 Aug 13; 52(15):4623-30.
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